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40 Possible Causes for Enlargement of the Spleen, Herpes Zoster, Hyperglobulinemia

  • Chronic Lymphocytic Leukemia

    The disease often involves enlargement of lymph nodes in various parts of the body as well as enlargement of the spleen.[cancer.unm.edu] They should also seek early medical attention if they develop viral or other infections and know how to recognise shingles or herpes zoster, two common viral infections associated[leukaemia.org.nz] CLL can also become apparent on the skin in the form of pruritus , chronic urticarial , mycosis and herpes zoster.[lecturio.com]

  • Non-Hodgkin Lymphoma

    It is characterized by hyperglobulinemia, excess bence-jones proteins (free monoclonal immunoglobulin light chains) in the urine, skeletal destruction, bone pain, and fractures[icd9data.com] They can also find an enlarged liver or spleen. A number of tests can be used to diagnose NHL. Your lymph nodes will swell any time your body is fighting an infection.[healthline.com] A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue.[icd9data.com]

  • Waldenstrom Macroglobulinemia

    Bing J et al. (1937) Reports of a third case of hyperglobulinemia with affection of the central nervous system on a toxi-infectious basis.[doi.org] For example, accumulation of these cells can lead to an enlarged liver (hepatomegaly), spleen (splenomegaly), or lymph nodes (lymphadenopathy).[ghr.nlm.nih.gov] zoster prophylaxis should be considered for patients receiving these regimens. e These regimens are associated with treatment-related neuropathy and should be avoided in[cancertherapyadvisor.com]

  • Multiple Myeloma

    Other symptoms can include stroke , gastrointestinal disorders, enlarged liver , diminished spleen function , diminished function of the adrenal and other endocrine glands[en.wikipedia.org] zoster). are pregnant or plan to become pregnant.[darzalex.com] Acyclovir to prevent reactivation of varicella zoster virus (herpes zoster) in multiple myeloma patients receiving bortezomib therapy. Cancer. Jan 1 2009;115(1):229-32.[web.archive.org]

  • Hodgkin's Disease

    Hodgkin's disease is a specific malignant disease which most frequently first manifests itself clinically by enlargement of the lymph glands and spleen accompanied by toxemia[annals.org] Hepatosplenomegaly: the enlargement of both the liver and spleen caused by the same disease.[slideshare.net] Occasionally, the spleen enlarges (under the left rib cage) and can be felt by the doctor.[medbroadcast.com]

  • Primary Biliary Cirrhosis

    Complications from Primary Biliary Cirrhosis can include hypersplenism (enlargement of the spleen), hepatic encephalopathy (confusion or coma resulting from liver failure)[disability-benefits-help.org] zoster and pulmonary abscess.[ncbi.nlm.nih.gov] Enlarged spleen (splenomegaly).[mayoclinic.org]

  • Congenital Liver Cirrhosis

    Other later symptoms, some due to complications, include: Reddened palms Loss of body hair Enlarged liver Enlarged spleen Appearance of thin, purplish-red, spidery looking[chp.edu] […] group (Cytomegalovirus, Herpes simplex, Varicella/Zoster, Epstein-Barr). li-6-3 Other viruses rarely affecting the liver (Adenoviruses, Coxsackie, ECHO, Rubella, Yellow fever[meddean.luc.edu] People with congenital hepatic fibrosis have an enlarged liver and spleen (hepatosplenomegaly). The liver is also abnormally shaped.[ghr.nlm.nih.gov]

  • Acquired Immunodeficiency Syndrome

    In ALPS, unusually high numbers of white blood cells called lymphocytes accumulate in the lymph nodes, liver, and spleen and can lead to enlargement of these organs.[niaid.nih.gov] We report a case of a 10-year-old boy previously immunized to Varicella who presented with herpes zoster with hematogenous dissemination as the Acquired Immunodeficiency Syndrome-defining[ncbi.nlm.nih.gov] zoster ophthalmicus (2.4%), and blepharitis (1.6%).[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    Enlargement of the spleen Mononucleosis may cause enlargement of the spleen.[mayoclinic.com] PubMed PubMed Central Google Scholar Weidmann M, Meyer-König U, Hufert FT: Rapid detection of Herpes simplex virus and Varicella-zoster virus infections by real time PCR.[dx.doi.org] Mono can cause liver inflammation ( hepatitis ) and enlargement of the spleen.[rxlist.com]

  • Polycythemia Vera

    […] hematopoietic stem cells, characterized by increased blood volume, bone marrow hyperplasia, redness of the skin, and splenic enlargement. polycythemia vera polycythemia vera Hyperglobulinemia[medical-dictionary.thefreedictionary.com] If left untreated, you could experience an enlarged spleen, peptic ulcers, blood disorders, gout, open sores in the small intestine, and life-threatening blood clots.[disabilitybenefitscenter.org] As reported in a prior analysis, the rate of herpes zoster was higher in the ruxolitinib arm. The RESPONSE study was conducted at 90 sites worldwide.[medicalnewstoday.com]

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