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40 Possible Causes for Enlargement of the Spleen, Herpes Zoster, Hyperglobulinemia

  • Chronic Lymphocytic Leukemia

    The disease often involves enlargement of lymph nodes in various parts of the body as well as enlargement of the spleen.[] They should also seek early medical attention if they develop viral or other infections and know how to recognise shingles or herpes zoster, two common viral infections associated[] CLL can also become apparent on the skin in the form of pruritus , chronic urticarial , mycosis and herpes zoster.[]

  • Non-Hodgkin Lymphoma

    It is characterized by hyperglobulinemia, excess bence-jones proteins (free monoclonal immunoglobulin light chains) in the urine, skeletal destruction, bone pain, and fractures[] They can also find an enlarged liver or spleen. A number of tests can be used to diagnose NHL. Your lymph nodes will swell any time your body is fighting an infection.[] A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue.[]

  • Waldenstrom Macroglobulinemia

    Bing J et al. (1937) Reports of a third case of hyperglobulinemia with affection of the central nervous system on a toxi-infectious basis.[] For example, accumulation of these cells can lead to an enlarged liver (hepatomegaly), spleen (splenomegaly), or lymph nodes (lymphadenopathy).[] zoster prophylaxis should be considered for patients receiving these regimens. e These regimens are associated with treatment-related neuropathy and should be avoided in[]

  • Multiple Myeloma

    Other symptoms can include stroke , gastrointestinal disorders, enlarged liver , diminished spleen function , diminished function of the adrenal and other endocrine glands[] zoster). are pregnant or plan to become pregnant.[] Acyclovir to prevent reactivation of varicella zoster virus (herpes zoster) in multiple myeloma patients receiving bortezomib therapy. Cancer. Jan 1 2009;115(1):229-32.[]

  • Hodgkin's Disease

    Hodgkin's disease is a specific malignant disease which most frequently first manifests itself clinically by enlargement of the lymph glands and spleen accompanied by toxemia[] Hepatosplenomegaly: the enlargement of both the liver and spleen caused by the same disease.[] Occasionally, the spleen enlarges (under the left rib cage) and can be felt by the doctor.[]

  • Primary Biliary Cirrhosis

    Complications from Primary Biliary Cirrhosis can include hypersplenism (enlargement of the spleen), hepatic encephalopathy (confusion or coma resulting from liver failure)[] zoster and pulmonary abscess.[] Enlarged spleen (splenomegaly).[]

  • Congenital Liver Cirrhosis

    Other later symptoms, some due to complications, include: Reddened palms Loss of body hair Enlarged liver Enlarged spleen Appearance of thin, purplish-red, spidery looking[] […] group (Cytomegalovirus, Herpes simplex, Varicella/Zoster, Epstein-Barr). li-6-3 Other viruses rarely affecting the liver (Adenoviruses, Coxsackie, ECHO, Rubella, Yellow fever[] People with congenital hepatic fibrosis have an enlarged liver and spleen (hepatosplenomegaly). The liver is also abnormally shaped.[]

  • Acquired Immunodeficiency Syndrome

    In ALPS, unusually high numbers of white blood cells called lymphocytes accumulate in the lymph nodes, liver, and spleen and can lead to enlargement of these organs.[] We report a case of a 10-year-old boy previously immunized to Varicella who presented with herpes zoster with hematogenous dissemination as the Acquired Immunodeficiency Syndrome-defining[] zoster ophthalmicus (2.4%), and blepharitis (1.6%).[]

  • Infectious Mononucleosis

    Enlargement of the spleen Mononucleosis may cause enlargement of the spleen.[] PubMed PubMed Central Google Scholar Weidmann M, Meyer-König U, Hufert FT: Rapid detection of Herpes simplex virus and Varicella-zoster virus infections by real time PCR.[] Mono can cause liver inflammation ( hepatitis ) and enlargement of the spleen.[]

  • Polycythemia Vera

    […] hematopoietic stem cells, characterized by increased blood volume, bone marrow hyperplasia, redness of the skin, and splenic enlargement. polycythemia vera polycythemia vera Hyperglobulinemia[] If left untreated, you could experience an enlarged spleen, peptic ulcers, blood disorders, gout, open sores in the small intestine, and life-threatening blood clots.[] As reported in a prior analysis, the rate of herpes zoster was higher in the ruxolitinib arm. The RESPONSE study was conducted at 90 sites worldwide.[]

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