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299 Possible Causes for Enlargement of the Spleen, Lactate Dehydrogenase Increased

  • Portal Cirrhosis

    Other complications Portal hypertension may cause the spleen to become enlarged.[upmc.com] Other later symptoms, some due to complications, include: Reddened palms Loss of body hair Enlarged liver Enlarged spleen Appearance of thin, purplish-red, spidery looking[chp.edu] Splenomegaly Increased pressure in the portal vein is conducted to the splenic vein resulting in congestive enlargement of the spleen.[pathwaymedicine.org]

  • Macronodular Cirrhosis

    Splenomegaly Increased pressure in the portal vein is conducted to the splenic vein resulting in congestive enlargement of the spleen.[pathwaymedicine.org] […] of the spleen, enlargement of the veins in the oesophagus (gullet) (which may rupture to cause severe bleeding), and accumulation of fluid in the peritoneal cavity (ascites[flipper.diff.org] Breast enlargement in men. Fluid accumulation in the abdomen and legs. Enlarged spleen. Diarrhea; stool may be black or bloody. Bleeding and bruising.[nmihi.com]

  • Chronic Lymphocytic Leukemia

    The disease often involves enlargement of lymph nodes in various parts of the body as well as enlargement of the spleen.[cancer.unm.edu] CLL leads to unspecific symptoms such as general malaise and weakness, fever, night sweats, weight loss and enlarged lymph nodes, spleen or liver.[symptoma.com] (enlarged liver and spleen), anemia (low red blood cell count), or thrombocytopenia (low platelet count).[cancer.unm.edu]

  • Splenic Subcapsular Hematoma

    Enlargement of the spleen (for example, due to Epstein-Barr virus causing infectious mononucleosis ) makes the spleen more susceptible to injury.[merckmanuals.com] Intraparenchymal hematomas appear broader; irregularly shaped; and hypodense, isodense, or even hyperdense and cause enlargement of the spleen and mass effect.[e-ultrasonography.org] These findings were consistent with the diagnosis of a ruptured enlarged spleen secondary to acute infectious mononucleosis.[omicsonline.org]

  • Cardiac Cirrhosis

    […] and firm, often associated with slight enlargement of the spleen Modest elevations of ALT, AST, LDH, r-GT,ALP, T-Bil small decreases in albumin levels Liver function abnormalities[powershow.com] It is marked by jaundice, abdominal pain, steatorrhea, and enlargement of the liver and spleen. congestive cirrhosis cirrhosis resulting from increased hepatic venous pressure[medical-dictionary.thefreedictionary.com] Symptom Cardiac cirrhosis Symptoms Common symptoms Malignant jaundice Hepatocarcinoma Large abdominal distension Jugular vein Angiotensory Spleen enlargement Portal Hypertension[healthfrom.com]

  • Infectious Mononucleosis

    Enlargement of the spleen Mononucleosis may cause enlargement of the spleen.[mayoclinic.com] Mono can cause liver inflammation ( hepatitis ) and enlargement of the spleen.[rxlist.com] If you have mononucleosis, it's important to be careful of certain complications such as an enlarged spleen. Rest and adequate fluids are keys to recovery.[mayoclinic.com]

  • Thalassemia

    At the end of the treatment period, Hb and HbF increased by 2.5   1.8 g/dL and 2.5   1.6 g/dL, while bilirubin, lactate dehydrogenase, and the nucleated red blood cell count[ncbi.nlm.nih.gov] Occasionally, complications occur involving slight enlargement of the spleen.[britannica.com] Causes A number of infections and diseases may cause an enlarged spleen. The enlargement of the spleen may be temporary, depending on treatment.[mayoclinic.org]

  • Hereditary Spherocytosis

    Reticulocytosis, increased bilirubin, increased lactate dehydrogenase, increased urinary and fecal urobilinogen, and decreased haptoglobin, reflect increased erythrocyte production[clinicaladvisor.com] […] of the spleen, reticulocytosis, and mild jaundice[merriam-webster.com] Other biochemical changes of hemolysis also are also present, including: increased lactate dehydrogenase (LDH) increased unconjugated bilirubin decreased serum haptoglobin[steadyhealth.com]

  • Cooley's Anemia

    […] and a decreasing trend in the serum lactate dehydrogenase (LDH) and serum unconjugated bilirubin levels.[onlinelibrary.wiley.com] […] of the spleen.[unicosandiego.org] […] of the spleen, and body deformities associated with expansion of the bone marrow.[britannica.com]

  • Acute Alcohol Intoxication

    Abdominal tenderness on palpation and enlargement of the liver and occasionally the spleen may reflect the presence of acute or chronic liver disease.[cjasn.asnjournals.org]

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