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378 Possible Causes for Enlargement of the Spleen, Lactate Dehydrogenase Increased

  • Infectious Mononucleosis

    Enlargement of the spleen Mononucleosis may cause enlargement of the spleen.[] If the spleen is enlarged, the patient may complain of tenderness to palpation.[] An enlarged spleen can rupture easily — causing internal bleeding and abdominal pain — and require emergency surgery.[]

  • Chronic Lymphocytic Leukemia

    […] chemicals measured in blood tests , for example lactate dehydrogenase (LDH) or calcium.[] The disease often involves enlargement of lymph nodes in various parts of the body as well as enlargement of the spleen.[] The upper limit of the normal range (ULN) for the lactate dehydrogenase level was 250 U per liter.[]

  • Portal Cirrhosis

    Splenomegaly (enlarged spleen) e. Hepatic encephalopathy (drowsiness or confusion due to inability of the liver to break down toxins in the blood) f.[] Other complications Portal hypertension may cause the spleen to become enlarged.[] Other later symptoms, some due to complications, include: Reddened palms Loss of body hair Enlarged liver Enlarged spleen Appearance of thin, purplish-red, spidery looking[]

  • Cardiac Cirrhosis

    […] and firm, often associated with slight enlargement of the spleen Modest elevations of ALT, AST, LDH, r-GT,ALP, T-Bil small decreases in albumin levels Liver function abnormalities[] Enlargement of the spleen (splenomegaly). Portal hypertension can also cause changes to the spleen.[] […] of the salivary glands Enlarged liver and spleen on examination Reduced body hair, smaller testes and enlarged breasts in males Menstrual irregularities in females What are[]

  • Macronodular Cirrhosis

    Splenomegaly Increased pressure in the portal vein is conducted to the splenic vein resulting in congestive enlargement of the spleen.[] […] of the spleen, enlargement of the veins in the oesophagus (gullet) (which may rupture to cause severe bleeding), and accumulation of fluid in the peritoneal cavity (ascites[] Breast enlargement in men. Fluid accumulation in the abdomen and legs. Enlarged spleen. Diarrhea; stool may be black or bloody. Bleeding and bruising.[]

  • Splenic Subcapsular Hematoma

    Intraparenchymal hematomas appear broader; irregularly shaped; and hypodense, isodense, or even hyperdense and cause enlargement of the spleen and mass effect.[] Plain abdominal radiographs can show enlargement of the spleen with medial displacement of the gastric bubble and elevation of the left hemidiaphragm with impaired motion.[] -opportunistic infectons and lymphoma can affect the spleen -most commonly, an enlarged spleen Associated with AIDS patients: -tuberculosis -lymphoma -Kaposi sarcoma AIDS[]

  • Neonatal Hepatitis

    The infant with biliary atresia is also jaundiced and has an enlarged liver, but is growing well and does not have an enlarged spleen.[] A pediatric specialist may find an enlarged liver or spleen during an examination of your child’s body. Blood Tests .[] Hepatomegaly- Liver enlargement. Splenomegaly- Enlarged spleen .[]

  • Cryoglobulinemia

    […] liver or spleen Numbness, tingling or weakness Kidney damage Cleveland Clinic News & More Cleveland Clinic News & More[] Essential mixed cryoglobulinemia is characterized by joint pains and swelling ( arthritis ), enlargement of the spleen, skin vasculitis with purplish patches, and nerve and[] […] from normal to white to a purplish-blue color) with cold, called "Raynaud's Phenomenon" Weight loss High blood pressure Swelling of ankles and legs Skin ulcers and gangrene Enlarged[]

  • Alcoholic Hepatitis

    Your doctor will also perform a biopsy to see if you have an enlarged liver or spleen.[] Your doctor will also perform a physical exam to see if you have an enlarged liver or spleen . They may decide to order tests so they can confirm your diagnosis.[] Portal hypertension which can cause spleen enlargement. When this happens, it can trap white blood cells and platelets (these cells aid in clotting).[]

  • Familial Myelofibrosis

    Enlarged liver and spleen can be palpated, but these organs should also be depicted by sonography.[] During fetal development, since bones and thus the bone marrow develop later, therefore, the liver is enlarged during development.[] Because of extramedullary hematopoiesis, myelofibrosis is usually associated with enlarged liver and spleen, which may cause abdominal pain, nausea, loss of appetite and weight[]

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