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1,097 Possible Causes for Enlargement of the Spleen, Palpitations, Splenomegaly

  • Primary Myelofibrosis

    Virtually all patients with primary myelofibrosis have an enlarged spleen (splenomegaly) when they are first diagnosed.[leukaemia.org.au] Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[ncbi.nlm.nih.gov] Anemia may cause easy fatigability, weakness, dyspnea, and palpitations. Splenomegaly may result in early satiety and left upper quadrant discomfort.[emedicine.medscape.com]

  • Thalassemia

    Many conditions — including infections, liver disease and some cancers — can cause an enlarged spleen, also known as splenomegaly (spleh-no-MEG-uh-lee).[mayoclinic.org] Patients may claim frequent headaches, dizziness, exertional dyspnea and palpitations.[symptoma.com] […] taking deferiprone with food. 1 Possibility of reddish/brown discoloration of the urine, which is not harmful. 1 Importance of seeking immediate medical attention in case of palpitations[web.archive.org]

  • Chronic Lymphocytic Leukemia

    The disease often involves enlargement of lymph nodes in various parts of the body as well as enlargement of the spleen.[cancer.unm.edu] One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov] […] thrombocytes, leading to symptoms of anemia and hemorrhagic diathesis, patients are pale, their performance is reduced, they complain of headaches and dizziness as well as palpitations[symptoma.com]

  • Familial Myelofibrosis

    Enlarged liver and spleen can be palpated, but these organs should also be depicted by sonography.[symptoma.com] The typical clinical features include marked splenomegaly, progressive anemia, . . .[nejm.org] BESREMi is approved as first-line monotherapy in adults for the treatment of Polycythaemia vera (PV) without symptomatic splenomegaly BESREMi showed high and durable hematologic[aoporphan.hu]

  • Schistosomiasis

    Within one or two months, you may notice the following: fever chills muscle aches cough diarrhea bloody urine or feces abdominal pain painful urination enlarged liver or spleen[healthline.com] Initial investigation showed signs of liver fibrosis, portal hypertension and splenomegaly.[ncbi.nlm.nih.gov] […] pain Abdominal swelling ( ascites ) Bloody diarrhea or blood in the stools Blood in the urine and painful urination Shortness of breath and coughing Weakness Chest pain and palpitations[medicinenet.com]

  • Hemolytic Anemia

    […] liver and spleen Exercise intolerance Fever Decrease in urine output How Is Hemolytic Anemia Treated?[luriechildrens.org] It results in hemolytic anemia and splenomegaly.[icd9data.com] Signs and symptoms may include fatigue, dizziness, heart palpitations, pale skin, headache, confusion, jaundice, and a spleen or liver that is larger than normal.[nhlbi.nih.gov]

  • Infective Endocarditis

    Heart murmurs are present in over 85% of individuals with infective endocarditis, and 60% have enlarged spleens.[rarediseases.org] Additional findings may include splenomegaly, gallop or arrhythmia, pericardial or pleural rubs, rales, pallor, acute septic monoarticular arthritis or delirium.[symptoma.com] At the same time, he complained of palpitation and a heart murmur was detected.[ncbi.nlm.nih.gov]

  • Anemia

    […] of the spleen with certain causes of anemia Next: When to Seek Medical Care »[web.archive.org] Her physical examination revealed anemic syndrome and an enormous splenomegaly extending beyond the umbilical area.[ncbi.nlm.nih.gov] Agnogenic myeloid metaplasia, which is characterized by anemia with primary bone marrow involvement, involves gradual bone marrow fibrosis, extramedullary hematopoiesis, and splenomegaly[emedicine.com]

  • Myelodysplasia

    […] nodes, liver, and spleen; signs of disease outside the bone marrow; and profound cytopenias (reductions in the number of blood cells).[iwmf.com] We present a 2-year-old boy with splenomegaly, leukocytosis, thrombocytopenia, anemia, and excess myeloblasts with easily seen Auer rods, and marked dysgranulopoiesis and[ncbi.nlm.nih.gov] In moderate anemia, almost all patients experience some fatigue, which may be accompanied by heart palpitations, shortness of breath, and pale skin.[mds-foundation.org]

  • Bacterial Endocarditis

    Moderate enlargement of the spleen is seen in 30-40% of patients.[remedyland.com] RESULTS--Group A--9 patients aged 8-58 years, 3 men, all them with cardiac murmurs, fever and anemia, 5 with splenomegaly.[bases.bireme.br] Fever over 100.4 F ( 38.0 C) Sweats Severe abdominal or flank pain Bloody urine Return of symptoms such as loss of appetite, weight loss, paleness, headache, or weakness Palpitations[saintlukeskc.org]

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