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348 Possible Causes for Enlargement of the Spleen, Palpitations, Splenomegaly

  • Chronic Lymphocytic Leukemia

    The disease often involves enlargement of lymph nodes in various parts of the body as well as enlargement of the spleen.[] In the physical examination, generalized lymphadenopathy and hepato- and/or splenomegaly may be noted.[] […] welts) or rash Itching Swelling of your lips, tongue, throat, or face Sudden cough Shortness of breath, difficulty breathing, or wheezing Weakness Dizziness or feel faint Palpitations[]

  • Infectious Mononucleosis

    Enlargement of the spleen Mononucleosis may cause enlargement of the spleen.[] Clinical estimates of splenomegaly are fallible.[] He also complained of palpitations and diaphoresis. His heart rate was 165 beats/min and his blood pressure was irregularly irregular at 160/100 mm Hg.[]

  • Thalassemia

    Occasionally, complications occur involving slight enlargement of the spleen.[] Approach to the adult patient with splenomegaly and other splenic disorders. . Accessed June 14, 2016. Splenomegaly. Merck Manual Professional Version. .[] Patients may claim frequent headaches, dizziness, exertional dyspnea and palpitations.[]

  • Familial Myelofibrosis

    Enlarged liver and spleen can be palpated, but these organs should also be depicted by sonography.[] Because of extramedullary hematopoiesis, myelofibrosis is usually associated with enlarged liver and spleen, which may cause abdominal pain, nausea, loss of appetite and weight[] The clinical presentation of FM is that of extramedullary hematopoiesis and pancytopenia: Because of chronic bone marrow failure, hematopoiesis takes place in liver and spleen[]

  • Primary Myelofibrosis

    A physical exam of the abdomen may reveal enlargement of the spleen, the liver, or both.Blood tests are also used in diagnosis.[] Abstract We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[] Symptoms of anaemia are common and include unexplained tiredness, weakness, shortness of breath and palpitations.[]

  • Schistosomiasis

    Initial investigation showed signs of liver fibrosis, portal hypertension and splenomegaly.[] Within one or two months, you may notice the following: fever chills muscle aches cough diarrhea bloody urine or feces abdominal pain painful urination enlarged liver or spleen[] […] pain Abdominal swelling ( ascites ) Bloody diarrhea or blood in the stools Blood in the urine and painful urination Shortness of breath and coughing Weakness Chest pain and palpitations[]

  • Hypersplenism

    Infections: There is enlargement of the spleen in acute pyogenic infection. In septicemia, the spleen is enlarged and called septic spleen.[] RESULTS: While 38 patients displayed splenomegaly, 121 showed normal spleen volumes at 6 months after LDLT (LDLT).[] Palpitations — Throbbing or pulsation. Heart palpitations usually infer an irregular or rapid rhythm.[]

  • Acute Lymphoblastic Leukemia

    Splenomegaly and thrombocytopenia were frequently observed more in CD200 patients. Increased frequency of CD34 was associated with CD200 and CD56 patients.[] […] liver or spleen Pinpoint red spots on the skin (petechiae) Swollen lymph nodes in the neck, under arms, and groin Night sweats These symptoms can occur with other conditions[] Symptoms of anemia are common and include fatigue, dizziness, palpitations, and dyspnea upon even mild exertion. Other patients present with signs of bleeding.[]

  • Chagas Disease

    Signs of Chagas disease may include: Disease of the heart muscle Enlarged liver and spleen Enlarged lymph nodes Irregular heartbeat Rapid heartbeat Tests include: Blood culture[] […] over several weeks More general symptoms include: headache pallor myalgia dyspnoea oedema in inferior limbs or face abdominal pain cough hepatomegaly rash painful nodules splenomegaly[] Snapshot A 58-year-old man presents to the clinic with a 2 month history of cough, dyspnea on exertion, palpitations, and orthopnea.[]

  • Infective Endocarditis

    This score includes clinical, epidemiological (male, fever, splenomegaly, clubbing, vascular disease and stroke) and biological criteria (Leucocytes 10,000/mm3, sedimentation[] Heart murmurs are present in over 85% of individuals with infective endocarditis, and 60% have enlarged spleens.[] At the same time, he complained of palpitation and a heart murmur was detected.[]

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