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447 Possible Causes for Enlargement of the Spleen, Petechiae

  • Chronic Lymphocytic Leukemia

    The disease often involves enlargement of lymph nodes in various parts of the body as well as enlargement of the spleen.[cancer.unm.edu] The most common treatment-related AEs (reported in at least 5 percent of patients) were headache (20 percent), an increased tendency to bruise (12 percent) and petechiae ([curetoday.com] Mucocutaneous bleeding and/or petechiae may be due to thrombocytopenia.[emedicine.medscape.com]

  • Hypersplenism

    Hypersplenism may occur in any condition in which there is enlargement of the spleen ( see splenomegaly).[oxfordreference.com] Figure 67-8 Petechiae and ecchymoses in a patient with idiopathic thrombocytopenic purpura. (Courtesy of Sidney Sussman, MD.)[5minuteconsult.com] Infections: There is enlargement of the spleen in acute pyogenic infection. In septicemia, the spleen is enlarged and called septic spleen.[labpedia.net]

  • Infectious Mononucleosis

    Enlargement of the spleen Mononucleosis may cause enlargement of the spleen.[mayoclinic.com] In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly, or atypical[ncbi.nlm.nih.gov] Conclusions and Relevance In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae[doi.org]

  • Thrombocytopenia

    […] a disorder that is causing the spleen to enlarge.[merckmanuals.com] Larger than petechiae, ecchymoses are purple, blue or yellow-green areas of skin that vary in size and shape.[en.wikipedia.org] A 20-month-old boy presented with a 2-day history of fever and systemic petechiae.[ncbi.nlm.nih.gov]

  • Leukemia

    Stage I: The patient has lymphocytosis and enlarged lymph nodes. The patient does not have an enlarged liver or spleen, anemia, or low levels of platelets.[cancer.net] These were petechiae/purpura (category derived from ‘petechiae’, ‘purpura’ and ‘petechiae/purpura’), mucosal bleeding (including ‘mucosal bleeding’ and ‘bleeding gums’), anorexia[doi.org] Radiation therapy Radiation therapy may be used to destroy leukemia cells, or to relieve pain or discomfort caused by an enlarged liver or spleen, or swollen lymph nodes.[cancercenter.com]

  • Myeloproliferative Disease

    In some cases there is also a slight enlargement of the spleen.[knowcancer.com] […] of splenic infarction and perisplenitis Clinical symptoms can include the following: Pallor (except in patients with polycythemia vera) Plethora secondary to polycythemia Petechiae[emedicine.com] In around a third of cases the spleen is very enlarged.[leukaemia.org.au]

  • Familial Myelofibrosis

    Enlarged liver and spleen can be palpated, but these organs should also be depicted by sonography.[symptoma.com] Because of extramedullary hematopoiesis, myelofibrosis is usually associated with enlarged liver and spleen, which may cause abdominal pain, nausea, loss of appetite and weight[symptoma.com] The clinical presentation of FM is that of extramedullary hematopoiesis and pancytopenia: Because of chronic bone marrow failure, hematopoiesis takes place in liver and spleen[symptoma.com]

  • Aplastic Anemia

    […] liver or spleen Oral thrush (white patches on a red, moist, swollen surface, occurring anywhere in the mouth) The symptoms of aplastic anemia may resemble other blood disorders[chop.edu] Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia (infections).[merckmanuals.com] We report a case of 6-year-old South Asian girl presenting with bruises, petechiae, and recent history of loose stools.[ncbi.nlm.nih.gov]

  • Sunburn

    An enlarged spleen can rupture easily, causing severe abdominal pain and requiring emergency surgery.[livestrong.com] Most health care providers recommend avoiding sports for at least a month after the symptoms disappear, especially if your spleen is enlarged.[livestrong.com] Other signs include: Fever, sometimes up to 103 degrees Fahrenheit Very sore throat Swollen lymph glands Headaches Muscles that ache Enlarged or swollen liver and spleen Common[livestrong.com]

  • Primary Myelofibrosis

    A physical exam of the abdomen may reveal enlargement of the spleen, the liver, or both.Blood tests are also used in diagnosis.[en.wikipedia.org] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net] Petechiae (flat, red, pinpoint spots under the skin that are caused by bleeding). Fever. Night sweats. Weight loss.[navigatingcare.com]

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