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2,736 Possible Causes for Eosinophilia, Keratoderma of Palms and Soles, Palmar Hyperlinearity

  • Atopic Dermatitis

    We present the case of a 6 year old patient that developed de novo atopic dermatitis, eosinophilia and high levels of total IgE under systemic treatment with tacrolimus.[ncbi.nlm.nih.gov] Among patients, reduced level of monomeric filaggrin and NMF correlated with the presence of FLG mutations and clinical phenotypes such as xerosis, palmar hyperlinearity and[ncbi.nlm.nih.gov] […] more prevalent in the acute phase, and TH1 predominates in the chronically affected skin. [1] Patients with atopic dermatitis have elevated serum IgE levels, peripheral eosinophilia[emedicine.medscape.com]

    Missing: Keratoderma of Palms and Soles
  • Exfoliative Dermatitis

    We present the first two cases of this adverse effect of the drug, combined with eosinophilia but no systemic symptoms.[ncbi.nlm.nih.gov] Keratoderma of palms and/or soles was seen in 79%. Laboratory findings were normal, except for an increased IgE level in 69% of the patients studied.[ncbi.nlm.nih.gov] […] develops ie thickened skin on the palms and soles After several weeks, erythema and scaling of the scalp can lead to hair loss The nails become thickened, ridged and may[pcds.org.uk]

    Missing: Palmar Hyperlinearity
  • Eosinophilic Fasciitis

    The palms and soles had severe confluent keratoderma (Figure 2A).[mdedge.com] In addition to systemic sclerosis, the prototype idiopathic fibrosing disorder, these conditions include the eosinophilia-myalgia syndrome, epidemic toxic oil syndrome, eosinophilic[ncbi.nlm.nih.gov] ; Management of Hypereosinophilic Syndromes; and Novel Therapies for Eosinophilic Disorders.[books.google.com]

    Missing: Palmar Hyperlinearity
  • Mycosis Fungoides

    […] precedes Sx by up to 2 yrs; the leukemic phase–Sezary syndrome–occurs in 80% and is accompanied by fever, weight loss, lymphadenopathy, hepatosplenomegaly, lung involvement, eosinophilia[medical-dictionary.thefreedictionary.com] Additional clinical findings include temperature dysregulation, keratoderma (skin thickening) of the palms and soles, alopecia, nail-plate dystrophy, and ectropion of the[nursingcenter.com] Drug reaction with eosinophilia and systemic symptoms (DRESS): a clinical update and review of current thinking. Clin Exp Dermatol. 2011 ;36(1): 6 – 11.[archivesofpathology.org]

    Missing: Palmar Hyperlinearity
  • Ichthyosis

    Consequently, defects in epidermal barrier function lead to pruritus, a susceptibility to skin infections and AD (often with elevation of total immunoglobulin E levels and eosinophilia[onlinelibrary.wiley.com] Patient ID-58 presented brown scales, sparing of antecubital and popliteal areas and normal palms and soles ( a ).[ojrd.biomedcentral.com] Palms and soles show accentuated creases and when affecting the palms this sign is referred to as palmar hyperlinearity or as “ichthyosis palms”.[medizin.uni-muenster.de]

  • Sézary Syndrome

    All patients' palms and soles were evaluated for clinical evidence of keratoderma (hyperkeratosis) and for dermatophytosis (tinea pedis or unguum) by examining scales under[ncbi.nlm.nih.gov] All patients’ palms and soles were evaluated for clinical evidence of keratoderma (hyperkeratosis) and for dermatophytosis (tinea pedis or unguum) by examining scales under[doi.org] Other common signs and symptoms of this condition include hair loss (alopecia), skin swelling (edema), thickened skin on the palms of the hands and soles of the feet (palmoplantar[ghr.nlm.nih.gov]

    Missing: Palmar Hyperlinearity
  • Atopy

    It can be concluded that nasal cytology with eosinophilia assessment can be a useful tool for an early diagnosis of atopic disease in children.[ncbi.nlm.nih.gov] Smoking, age above 40 years, and blood eosinophilia may affect a good outcome for atopy. Poorly controlled asthma may lead to many long-term changes in the body.[symptoma.com] Bachert, Aggravation of bronchial eosinophilia in mice by nasal and bronchial exposure to Staphylococcus aureus enterotoxin B, Clinical & Experimental Allergy, 36, 8, (1063[doi.org]

    Missing: Keratoderma of Palms and Soles Palmar Hyperlinearity
  • Diffuse Palmoplantar Keratoderma

    Complete haemogram was normal except for eosinophilia (10%).[jemds.com] Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the palms and soles.[like2do.com] Diffuse hereditary palmoplantar keratodermas are the palmoplantar keratodermas that affect most of the palms and soles and are caused by a genetic abnormality.[dermnetnz.org]

    Missing: Palmar Hyperlinearity
  • Allergic Rhinitis

    Allergy Asthma Proc 21(2):85–88 PubMed CrossRef Google Scholar Jacobs RL, Freedman PM, Boswell RN (1981) Nonallergic rhinitis with eosinophilia (NARES syndrome): clinical[link.springer.com] Nonallergic rhinitis Non-allergic rhinitis Nonallergic rhinitis with eosinophilia Purulent rhinitis Rhinitis Rhinitis (nasal congestion) Rhinitis (nasal congestion), chronic[icd9data.com] A nasal smear could also be done and may show eosinophilia. The treatment of allergic rhinitis is three pronged.[symptoma.com]

    Missing: Keratoderma of Palms and Soles Palmar Hyperlinearity
  • Asthma

    Tropical pulmonary eosinophilia (TPE) is an exaggerated immunological response to filarial antigens mainly seen in adults in endemic areas and is uncommonly reported in children[ncbi.nlm.nih.gov] He had eosinophilia, and electroneuromyography demonstrated sensorimotor polyneuropathy.[ncbi.nlm.nih.gov] Transient eosinophilia was observed in approximately 1 in 7 dupilumab-treated patients.[ncbi.nlm.nih.gov]

    Missing: Keratoderma of Palms and Soles Palmar Hyperlinearity

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