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211 Possible Causes for Eosinophilia, Macrocytosis

  • Malignant Neoplasm

    Following improvements in therapy for childhood malignancies, the striking increase in survival rate over the past 30 years has led to the increase risk of developing second malignant neoplasms (SMNs). We report a case of colorectal carcinoma as a SMN, following treatment for rhabdomyosarcoma. The patient was[…][ncbi.nlm.nih.gov]

  • Diphyllobothrium Latum Infection

    […] in appetite (may be increased or decreased) (9) mechanical bowel obstruction (10) vomiting or defecating several proglottids or a whole worm Laboratory findings (1) mild eosinophilia[meducator3.net] Laboratory evaluation was remarkable for a hemoglobin of 14.7, with macrocytosis (MCV 100), and no eosinophilia.[healio.com] Blood examination may reveal a slight leukocytosis with eosinophilia and occasionally a megaloblastic anemia associated with B12 deficiency. C. Imaging.[antiinfectivedrugs.com]

  • Mercaptopurine

    In all the patients, blood eosinophilia disappeared under AZA treatment.[ncbi.nlm.nih.gov] Megabloblastic erythropoeisis or macrocytosis (production of large red blood cells).[dermnetnz.org] Hematologic: Leukopenia , anemia, eosinophilia, pancytopenia, thrombocytopenia , abnormal bleeding, bone marrow hypoplasia.[robholland.com]

  • Methotrexate

    Methotrexate toxicity in mucocutaneous areas is usually not associated with tissue eosinophilia.[ncbi.nlm.nih.gov] Common: GI symptoms (mucositis, nausea, dyspepsia, diarrhea), Skin (macular rash), Neurotoxicity, Macrocytosis.[errolozdalga.com] Acute or chronic interstitial pneumonitis, often associated with blood eosinophilia, may occur and deaths have been reported.[medicines.org.uk]

  • Pernicious Anemia

    Macrocytosis is defined as having the mean corpuscular volume (MCV) 100 fL.[ncbi.nlm.nih.gov] Diagnostic dilemmas could occur when patients with PA present with spuriously normal or high cobalamin levels, normocytic or microcytic anemia, non-anemic macrocytosis, autoimmune[ncbi.nlm.nih.gov] We describe a case of pernicious anemia (PA) in a patient affected by chronic hepatitis C and macrocytosis during IFN-alpha therapy.[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    Two children are described who presented at the age of 5 and 7 months with anaemia, a high white cell count with eosinophilia and thrombocytopenia.[ncbi.nlm.nih.gov] Children with Down syndrome (DS) display macrocytosis, thrombocytosis, and a 500-fold increased risk of developing megakaryocytic leukemia; however, the specific effects of[ncbi.nlm.nih.gov] His complete blood count was remarkable for neutrophilia and, notably, eosinophilia.[ncbi.nlm.nih.gov]

  • Acute Erythroblastic Leukemia

    ; The differential diagnosis of eosinophilia in neoplastic hematopathology; Transformation in myeloproliferative neoplasms; and Challenges in consolidated reporting of hematopoietic[books.google.com] Blood smear shows nucleated red cells at different stages with pathological features (macrocytosis, schistocytes, blast cells Bone marrow biopsy shows prevalence of erythroid[patient.info] […] leukemia with maturation 25% Better M3 Acute promyelocytic leukemia (APL) 10% Best M4 Acute myelomonocytic leukemia 20% Average M4 eos Acute myelomonocytic leukemia with eosinophilia[news-medical.net]

  • Phenytoin

    Laboratory results revealed an eosinophilia and elevated liver enzymes.[ncbi.nlm.nih.gov] While macrocytosis and megaloblastic anemia have occurred, these conditions usually respond to folic acid therapy.[healthyplace.com] A probable case of drug reaction with eosinophilia and systemic symptoms (DRESS) associated with consecutive use of three medications for seizure control is reported.[ncbi.nlm.nih.gov]

  • Amegakaryocytic Thrombocytopenia

    […] forms of Wiskott-Aldrich syndrome Clinical features and diagnosis Isolated nonimmune thrombocytopenia with decreased marrow megakaryocytes and high serum TPO levels Red cell macrocytosis[pathologyoutlines.com] […] core Normal bone marrow Bone Marrow Cellularity Hematopoiesis Non-tumorous Lesions of Bone Marrow Reactive Hematopoietic Changes Erythroid hyperplasia Myeloid Hyperplasia Eosinophilia[atlases.muni.cz]

  • Toxic Effect

    Neurological toxic effects can occur without anaemia or macrocytosis, and even when B12 levels are in the normal range.[gov.uk] Animals subjected to chronic poisoning with formalin administered by intraperitoneal injection develop fibrinous peritonitis, associated with marked eosinophilia.[jem.rupress.org]

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