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2,951 Possible Causes for Eosinophilia, Moderate Erythroderma, Palmar Hyperlinearity

  • Atopic Dermatitis

    We present the case of a 6 year old patient that developed de novo atopic dermatitis, eosinophilia and high levels of total IgE under systemic treatment with tacrolimus.[ncbi.nlm.nih.gov] Among patients, reduced level of monomeric filaggrin and NMF correlated with the presence of FLG mutations and clinical phenotypes such as xerosis, palmar hyperlinearity and[ncbi.nlm.nih.gov] […] more prevalent in the acute phase, and TH1 predominates in the chronically affected skin. [1] Patients with atopic dermatitis have elevated serum IgE levels, peripheral eosinophilia[emedicine.medscape.com]

    Missing: Moderate Erythroderma
  • Drug Eruptions

    Therefore, corticosteroids may be needed to treat patients with eosinophilia in clinical practice.[ncbi.nlm.nih.gov] The adverse reactions were moderately severe. Two had erythroderma with hepatitis, and one, Steven Johnson Syndrome.[ncbi.nlm.nih.gov] Hypersensitivity Syndrome (HSS) or Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) is a severe cutaneous drug reaction with often a long duration of eruption and[ncbi.nlm.nih.gov]

    Missing: Palmar Hyperlinearity
  • Drug Hypersensitivity

    To decrease the ambiguity of the denomination of hypersensitivity syndrome, we propose the term of DRESS (Drug Rash with Eosinophilia and Systemic Symptoms).[ncbi.nlm.nih.gov] The initial manifestation of MDH is mostly severe exanthema ( n 13, including 1 case of erythroderma) often with some eosinophilia and a moderate elevation of transaminases[karger.com] Eosinophilia was the most frequently occurring hematological abnormality ( 50% of the cases).[ncbi.nlm.nih.gov]

    Missing: Palmar Hyperlinearity
  • Sézary Syndrome

    There is a systemic increase in IL-4, IL-5 and IL-10 levels, which leads to an increase in peripheral eosinophilia and elevated IgE levels.[clinicaladvisor.com] […] clearing of erythroderma and pruritus associated with a significant decrease in Sezary cell counts.[thedoctorsdoctor.com] Lymphocytosis, monocytosis, and/or eosinophilia can be present on routine differential.[ispub.com]

    Missing: Palmar Hyperlinearity
  • Congenital Non-Bullous Ichthyosiform Erythroderma ARCI 10

    IPS is sometimes associated with atopy and eosinophilia, but it is doubtful whether it represents a true syndrome with extracutaneous manifestations.[medicaljournals.se] When examined at 2–37 years of age, all patients exhibited skin xerosis, fine or focal scaling (Fig. 1c), palmar hyperlinearity or keratoderma, and frequent occurrence of[medicaljournals.se] , and transient eosinophilia (Fig. 2) After a general recovery during the first months of life, patients will have only slight skin problems, in the form of a non-scaly ichthyosis[medicaljournals.se]

  • Ichthyosis

    Consequently, defects in epidermal barrier function lead to pruritus, a susceptibility to skin infections and AD (often with elevation of total immunoglobulin E levels and eosinophilia[onlinelibrary.wiley.com] Palms and soles show accentuated creases and when affecting the palms this sign is referred to as palmar hyperlinearity or as “ichthyosis palms”.[medizin.uni-muenster.de] Most affected individuals were born with a collodion membrane and later showed mild-to-moderate (nonbullous) congenital ichthyosiform erythroderma (CIE).[ncbi.nlm.nih.gov]

  • Atopy

    It can be concluded that nasal cytology with eosinophilia assessment can be a useful tool for an early diagnosis of atopic disease in children.[ncbi.nlm.nih.gov] Smoking, age above 40 years, and blood eosinophilia may affect a good outcome for atopy. Poorly controlled asthma may lead to many long-term changes in the body.[symptoma.com] Weiss Asthma, hay fever, and phlegm production associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE levels [4.] L.R.[archbronconeumol.org]

    Missing: Moderate Erythroderma Palmar Hyperlinearity
  • Asthma

    Tropical pulmonary eosinophilia (TPE) is an exaggerated immunological response to filarial antigens mainly seen in adults in endemic areas and is uncommonly reported in children[ncbi.nlm.nih.gov] He had eosinophilia, and electroneuromyography demonstrated sensorimotor polyneuropathy.[ncbi.nlm.nih.gov] Transient eosinophilia was observed in approximately 1 in 7 dupilumab-treated patients.[ncbi.nlm.nih.gov]

    Missing: Moderate Erythroderma Palmar Hyperlinearity
  • Allergic Rhinitis

    Nonallergic rhinitis Non-allergic rhinitis Nonallergic rhinitis with eosinophilia Purulent rhinitis Rhinitis Rhinitis (nasal congestion) Rhinitis (nasal congestion), chronic[icd9data.com] Allergy Asthma Proc 21(2):85–88 PubMed CrossRef Google Scholar Jacobs RL, Freedman PM, Boswell RN (1981) Nonallergic rhinitis with eosinophilia (NARES syndrome): clinical[link.springer.com] Eosinophilia detected on nasal smear plus negative skin tests suggests aspirin sensitivity or nonallergic rhinitis with eosinophilia (NARES).[msdmanuals.com]

    Missing: Moderate Erythroderma Palmar Hyperlinearity
  • Peeling Skin Syndrome Type A

    A rare autosomal recessive form of congenital, ichthyosis characterised by peeling of skin, erythema, pruritus, short stature, eosinophilia, increased IgE A rare autosomal[medical-dictionary.thefreedictionary.com] Palmar and plantar areas are spared or present erythema, slight thickening of the skin or palmar hyperlinearity. An underlying erythroderma is present.[sites.uclouvain.be] Inflammatory/Type B PSS: Laboratory tests classically show evidence of atopy including eosinophilia and elevated IgE.[dermatologyadvisor.com]

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