Create issue ticket

912 Possible Causes for Eosinophilia, Splenomegaly

  • Rheumatoid Arthritis

    It is extremely rare for RA to present as FS or develop after initially presenting as neutropaenia and splenomegaly.[ncbi.nlm.nih.gov] Abstract Biologics used in the treatment of rheumatoid arthritis (RA) rarely cause eosinophilia.[ncbi.nlm.nih.gov] Other: thyroid disorders, osteoporosis, depression, splenomegaly.[patient.info]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] Two children are described who presented at the age of 5 and 7 months with anaemia, a high white cell count with eosinophilia and thrombocytopenia.[ncbi.nlm.nih.gov] His complete blood count was remarkable for neutrophilia and, notably, eosinophilia.[ncbi.nlm.nih.gov]

  • Sarcoidosis

    In this report, we describe the case of a 12-year-old girl presenting with fatigue and weight loss, with a painless hepato-splenomegaly without additional clinical signs on[ncbi.nlm.nih.gov] Blood tests: FBC may show raised white count/eosinophilia or lymphopenia. Anaemia may be seen. ESR is often raised ( 65% of cases).[patient.info] Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia. Am. J. Respir. Crit.[doi.org]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Splenomegaly of more than 10 cm, basophilia and leukocytosis were associated with a shorter median survival but was not statistically significant.[ncbi.nlm.nih.gov] The bone marrow was consistent with myelomonocytic morphology with eosinophilia.[ncbi.nlm.nih.gov] The accelerated phase and blast crisis present with fever, splenomegaly, ecchymoses, bleeding, and bone pain.[symptoma.com]

  • Polycythemia Vera

    […] symptoms in the phase 3 RESPONSE study of patients with polycythemia vera with splenomegaly who experienced an inadequate response to or adverse effects from hydroxyurea.[ncbi.nlm.nih.gov] […] treatment with hydroxyurea and serial phlebotomies had been started, the patient developed hypereosinophilia, fitting the category of a myeloproliferative neoplasm with eosinophilia[ncbi.nlm.nih.gov] Cellular Phase PMF ET RBC Normal or Normal, or , may be hypochromatic or polychromatic , teardrop cells Normal or (iron deficient anemia) WBC , left shifted, basophilia, eosinophilia[surgpathcriteria.stanford.edu]

  • Acute Myelocytic Leukemia

    Typical symptoms are spongy and bleeding gums, anemia, fatigue, fever, dyspnea, moderate splenomegaly, joint and bone pain, and repeated infections.[medical-dictionary.thefreedictionary.com] […] often described in acute myelocytic leukemia (AML) French-American-British Cooperative Group subtypes M4 and M5, this patient was diagnosed with the variant AML-M4 with eosinophilia[ncbi.nlm.nih.gov] Cases of CMML with eosinophilia should be investigated for the PDGFRB abnormality and if it is found, the case should be classified as a myeloid neoplasm with eosinophilia[doi.org]

  • Systemic Lupus Erythematosus

    […] relapsing illness, with a variety of different presentations. [ 5 , 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info] In rare cases, pleural eosinophilia is associated with connective tissue disease.[ncbi.nlm.nih.gov] […] relapsing illness, with a variety of different presentations. [ 5, 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info]

  • Chronic Myelomonocytic Leukemia

    Splenomegaly is frequently seen and may be massive.[ncbi.nlm.nih.gov] We describe an unusual case of chronic myelomonocytic leukemia with severe eosinophilia having t(5;12)(q31;p13) with t(1;7)(q10;p10).[ncbi.nlm.nih.gov] The presence of a dominant neoplastic clone with FIP1L1-PDGFRA rearrangement was suspected on the basis of sudden onset of peripheral and bone marrow eosinophilia and confirmed[ncbi.nlm.nih.gov]

  • Sjogren's Syndrome

    On admission, she presented with anemia, elevated C-reactive protein levels, anasarca, and hepato-splenomegaly.[ncbi.nlm.nih.gov] Blood tests may reveal elevated erythrocyte sedimentation rate and transaminase levels, anemia, leukopenia, eosinophilia, hypergammaglobulinemia, presence of antinuclear antibodies[symptoma.com] […] development of NHL lymphoma include low complements (C3 and C4), presence of cryoglobulins, low CD4:CD8 ratio, persistence of unilateral or bilateral parotid gland enlargement, splenomegaly[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    Those complaints are generally associated with anemia and splenomegaly.[symptoma.com] In CML, the peripheral smear frequently shows immature granulocytes as well as absolute eosinophilia and basophilia.[merckmanuals.com] A 55-year-old man presented with splenomegaly (10 cm below left costal margin) and leucocytosis (145 10(9)/L).[ncbi.nlm.nih.gov]

Further symptoms

Similar symptoms