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1,184 Possible Causes for Eosinophilia, Splenomegaly

  • Malignant Neoplasm

    Following improvements in therapy for childhood malignancies, the striking increase in survival rate over the past 30 years has led to the increase risk of developing second malignant neoplasms (SMNs). We report a case of colorectal carcinoma as a SMN, following treatment for rhabdomyosarcoma. The patient was[…][ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] Mardivirin L, Valeyrie-Allanore L, Branlant-Redon E, Beneton N, Jidar K, et al. (2010) Amoxicillin-induced flare in patients with DRESS (Drug Reaction with Eosinophilia and[omicsonline.org] In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly, or atypical[ncbi.nlm.nih.gov]

  • Polycythemia Vera

    […] in the phase 3 RESPONSE study of patients with polycythemia vera with splenomegaly who experienced an inadequate response to or adverse effects from hydroxyurea.[ncbi.nlm.nih.gov] […] treatment with hydroxyurea and serial phlebotomies had been started, the patient developed hypereosinophilia, fitting the category of a myeloproliferative neoplasm with eosinophilia[ncbi.nlm.nih.gov] Cellular Phase PMF ET RBC Normal or Normal, or , may be hypochromatic or polychromatic , teardrop cells Normal or (iron deficient anemia) WBC , left shifted, basophilia, eosinophilia[surgpathcriteria.stanford.edu]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] Two children are described who presented at the age of 5 and 7 months with anaemia, a high white cell count with eosinophilia and thrombocytopenia.[ncbi.nlm.nih.gov] His complete blood count was remarkable for neutrophilia and, notably, eosinophilia.[ncbi.nlm.nih.gov]

  • Rheumatoid Arthritis

    It is extremely rare for RA to present as FS or develop after initially presenting as neutropaenia and splenomegaly.[ncbi.nlm.nih.gov] Biologics used in the treatment of rheumatoid arthritis (RA) rarely cause eosinophilia.[ncbi.nlm.nih.gov] […] anti-citruillated plasma antibody (ACPA): it is more than 80% sensitive and more than 95% specific elevated ESR or C-reactive protein Associations Felty syndrome : rheumatoid arthritis, splenomegaly[radiopaedia.org]

  • Hypereosinophilic Syndrome

    Massive splenomegaly was a great point of challenge for diagnosis.[journals.plos.org] Disorders Eosinophil Production and Function Eosinophilia Hypereosinophilic Syndrome Hypereosinophilic syndrome is a condition characterized by peripheral blood eosinophilia[merckmanuals.com] We present a 24-year-old-male with left lower quadrant abdominal pain, elevated eosinophil counts and splenomegaly.[ncbi.nlm.nih.gov]

  • Chronic Myelomonocytic Leukemia

    Splenomegaly is frequently seen and may be massive.[ncbi.nlm.nih.gov] We describe an unusual case of chronic myelomonocytic leukemia with severe eosinophilia having t(5;12)(q31;p13) with t(1;7)(q10;p10).[ncbi.nlm.nih.gov] The presence of a dominant neoplastic clone with FIP1L1-PDGFRA rearrangement was suspected on the basis of sudden onset of peripheral and bone marrow eosinophilia and confirmed[ncbi.nlm.nih.gov]

  • Aggressive Systemic Mastocytosis

    A 43 year-old woman presented with fever, abdominal pain, epato-splenomegaly, ascites, cholestasis, anemia, thrombocytopenia and previous diagnosis of sclerosing cholangitis[ncbi.nlm.nih.gov] We report a patient with aggressive systemic mastocytosis (SM), who exhibited eosinophilia and unusual destructive bone lesions.[ncbi.nlm.nih.gov] Retro-orbital injections of P815 NT cells in syngeneic DBA/2 mice resulted in rapid development of aggressive SM within 13-16 days characterized by splenomegaly, extramedullary[ncbi.nlm.nih.gov]

  • Schistosomiasis

    Initial investigation showed signs of liver fibrosis, portal hypertension and splenomegaly.[ncbi.nlm.nih.gov] Eosinophilia was the lead to schistosomiasis, although no systemic symptoms were reported.[ncbi.nlm.nih.gov] The hepatosplenic form of the disease is characterized by periportal hepatic fibrosis, pre-sinusoidal portal hypertension and splenomegaly.[ncbi.nlm.nih.gov]

  • Visceral Larva Migrans

    Follow-up showed increased physical activity, improved respiratory status, and resolution of splenomegaly.[ncbi.nlm.nih.gov] Airway hyperreactivity, extreme eosinophilia, and pulmonary physiologic impairment are the characteristic features.[ncbi.nlm.nih.gov] Clinical findings were pain, fever, anorexia, dizziness, dyspnea, weight loss, cough, hepatomegaly, splenomegaly and lymphadenopathy.[ijph.tums.ac.ir]

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