Epidermal Thinning Causes & Reasons

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Epidermal Thinning Symptom Checker: Possible causes include Vulvitis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Vulvitis

The biopsy specimen of the lesion revealed epidermal thinning, the absence of a horny and granular cell layer, and the presence of distinctive lozenge-shaped keratinocytes [ncbi.nlm.nih.gov]

Histological features of the condition include the predominant feature of subepidermal plasma cell infiltrates in a band-like pattern, epidermal thinning which is thought [clinicaldermatology.eu]

thinning, presence of distinctive lozenge-shaped keratinocytes with sparse dyskeratosis and spongiosis, and a dense inflammatory infiltrate of (A) T-lymphocytes (CD3 ), [ncbi.nlm.nih.gov]

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Insect Bite

Thinning of the portion of the epidermal cell layer that overlies the tips of dermal papillae (suprapapillary plates), and dilated, tortuous blood vessels within these papillae [doi.org]

Epidermal changes in psoriasiform dermatoses Table 5 Dermal changes in psoriasiform dermatitis This type of inflammatory dermatosis is characterised by the presence of regular epidermal [doi.org]

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Skin Atrophy

Moreover, calcipotriol is able to restore betamethasone-impaired HA synthesis in keratinocytes and prevent betamethasone-induced epidermal thinning in minipigs upon treatment [ncbi.nlm.nih.gov]

Histological analysis performed at day 29 showed significant epidermal thinning with topical steroids compared with SDZ ASM 981 1% cream or the vehicle. [ncbi.nlm.nih.gov]

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Stomatitis

Moreover, mucilages create a kind of water-retaining net, performing different functions : firstly, they tend to minimize evaporation at epidermal level by forming a thin [prodecopharma.com]

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Ganglion Cyst

An epidermoid cyst or epidermal inclusion cyst[1] is a benign cyst usually found on the skin. The cyst develops out of ectodermal tissue. [en.wikipedia.org]

Histologically, it is made of a thin layer of squamous epithelium. Signs and symptoms[edit] The epidermoid cyst may have no symptoms, or it may be painful when touched. [en.wikipedia.org]

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Hypogonadism

Androgens are responsible for sebaceous gland growth and differentiation, hair growth, and epidermal barrier homeostasis [1]. [dermnetnz.org]

Androgen deficiency results in: Dry, thin, and wrinkled skin Lack of hair growth on the chest, axilla, face, and genitals Lack of genital pigmentation Gynaecomastia Reduced [dermnetnz.org]

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Atopic Dermatitis

Animals using moderate to potent topical corticosteroids showed, in contrast, skin thinning, decreased subcutaneous tissue, and suppressed proliferation of epidermal cells [doi.org]

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Lipedema

Histological changes seen in lipedema include a thinning of the epidermal layer, thickening of the subcutaneous tissue layer, fibrosis of arterioles, tearing of elastic fibers [eurolymphology.org]

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Balanitis

[…] examination of tissue bit showing sub-epidermal connective tissue with dense lympho-plasmocytic inflammation with predominant plasma cells (H and E, 100) Click here to view [urologyannals.com]

Figure 2: Microscopic examination of tissue bit showing focal inflammation in surface epithelium and thinned out epidermis (H and E, 40) Click here to view Figure 3: Microscopic [urologyannals.com]

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Acanthosis Nigricans

Biopsy characteristically demonstrates epidermal hyperkeratosis and minimal to mild acanthosis,[33],[50] and an upward projection of the dermal papillae into a thinned overlying [ijpd.in]

Hyperpigmentation is generally the result of epidermal hyperkeratosis, but increased number of melanosomes in the stratum corneum is also seen in some patients.[5],[51] The [ijpd.in]

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Ichthyosis Vulgaris

The lipoxygenase genes play a role in the epidermal permeability layer. [emedicine.medscape.com]

As with lamellar ichthyosis, neonates with CIE are referred to as collodion babies, but, as children and adults, they show generalized red skin with thin, white scaling. [emedicine.medscape.com]

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Psoriasis

[…] and fibrosis, thinned follicular epithelium and fibrous tracts [ 15 ]. [omicsonline.org]

Histology of scalp psoriasis Features include classical epidermal changes of psoriasis and follicular-related changes like infundibular dilatation, perifollicular inflammation [omicsonline.org]

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Burn Injury

After engraftment, epidermal coverage was restored with a thin split-thickness skin graft. [ncbi.nlm.nih.gov]

First-generation film dressings (eg, thin films, hydrocolloidal hydrogel foams) are based on the concept that epidermal regeneration occurs best in a moist environment. [emedicine.medscape.com]

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Hashimoto Thyroiditis

Histologic examination reveals epidermal thinning. Increased dermal mucopolysaccharides cause water retention and, in turn, pale-colored skin. [ncbi.nlm.nih.gov]

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Alcohol Withdrawal

In the chronic phase, along with epidermal thinning, the dermal vessels are more dilated and tortuous, and the edema of the often atrophic papillary dermis is denser as is [dermatologyadvisor.com]

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Vitiligo

[…] suspensions Thin dermoepidermal grafts Suction epidermal grafting Punch minigrafting Cultured epidermis with melanocytes or cultured melanocyte suspensions See Treatment [emedicine.com]

Tattooing can be used to repigment depigmented skin in dark-skinned individuals Surgery The basic types of repigmentation surgery include the following [6, 7] : Noncultured epidermal [emedicine.com]

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Lingular Pneumonia

Secondary changes like acanthosis and hyperkeratosis were seen in 11 out of 14 cases (78.5%) and epidermal thinning and atrophy was noted in 1 case [Figure 7]. [idoj.in]

thinning and atrophy or acanthosis with excessive hyperkeratosis or pseudoepitheliomatous hyperplasia can also be noted. [idoj.in]

[…] caseation, surrounded by epitheliod histiocytes and multinucleate giant cells in the superficial epidermis with prominent peripheral lymphocytes. [1] Secondary changes like epidermal [idoj.in]

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Milium

In the papillary dermis the colloid substance was resolved by the electron microscopy into either wavy, thin filaments derived from the epidermal keratinocytes or typical [ncbi.nlm.nih.gov]

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Skin Neoplasm

The protein keratin stiffens epidermal tissue to form finger nails. [cancerindex.org]

Nails grow from a thin area called the 'NAIL MATRIX', growth of nails is about 1 mm per week on average. [cancerindex.org]

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Alopecia Areata

Histopathologic findings of the extragenital lichen sclerosus et atrophicus showed more significant epidermal thinning and cleft formation compared to genital lichen sclerosus [kiss.kstudy.com]

thinning and cleft formation. [kiss.kstudy.com]

[…] there were no symptoms significant to extragenital lichen sclerosus et atrophicus and pathologically extragenital lichen sclerosus et atrophicus showed more significant epidermal [kiss.kstudy.com]

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Lichen Sclerosus

An excisional biopsy showed epidermal thinning on the left side and invasion of the dermis by a tumor nest on the right side (A) (H&E, original magnification 10). [mdedge.com]

thinning due to estrogen deficiency but not as a primary therapy of LS. [ncbi.nlm.nih.gov]

REATMENT Hormonal therapy Estrogen is an effective treatment for postmenopausal vulvovaginal atrophy and should be considered in women with dyspareunia, labial fusion, or epidermal [ncbi.nlm.nih.gov]

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Extramammary Paget Disease

CONCLUSIONS: Anogenital PD was more frequently associated with epidermal hyperplasia than axillary PD. [thedoctorsdoctor.com]

Histologically, it was composed of anastomosing thin epithelial strands with follicular differentiation. [thedoctorsdoctor.com]

The stroma beneath the hyperplastic epidermis tended to be rich in thin collagen fibers and fibroblasts. [thedoctorsdoctor.com]

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Squamous Cell Carcinoma of the Skin

[…] evaluation demonstrates full- thickness epidermal atypia, with more pronounced nuclear polymorphism and apoptosis 14.  Other features include confluent parakeratosis, and [slideshare.net]

Bowen's Disease  typically appears as a reddish-brown  scaly patch or thin plaque on the sun-exposed head, neck, extremities, or trunk of an older individual  On histopathologic [slideshare.net]

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Malignant Angioendotheliomatosis

Secondary changes like acanthosis and hyperkeratosis were seen in 11 out of 14 cases (78.5%) and epidermal thinning and atrophy was noted in 1 case [Figure 7]. [idoj.in]

thinning and atrophy or acanthosis with excessive hyperkeratosis or pseudoepitheliomatous hyperplasia can also be noted. [idoj.in]

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Ventral Hernia

anastomosis of rete ridges, and whiteness of epidermal cells due to intracellular edema. [ncbi.nlm.nih.gov]

Focal Epithelial Hyperplasia (Heck disease) Focal epithelial hyperplasia is characterized by acanthosis, blunting, hyperplastic mucosa with thin parakeratotic stratum corneum [ncbi.nlm.nih.gov]

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Erythroplasia of Queyrat

Key histologic features of Zoon balanitis include epidermal thinning, possibly with some superficial erosion. [aafp.org]

Histopathologic examination revealed epidermal thinning, spongiosis, and a dense subepidermal infiltrate composed of plasma cells and neutrophils. [aafp.org]

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Steroid Atrophy

Moreover, calcipotriol is able to restore betamethasone-impaired HA synthesis in keratinocytes and prevent betamethasone-induced epidermal thinning in minipigs upon treatment [genoskin.com]

Before treatment all patients had very thin skin, severe laxity, purpura and echymoses and teleangiectasia. [llogo.hu]

Epidermal thickness increased from 0.11 to 0.28 mm, dermal thickness from 0.80 to 1.55 mm and skin elasticity from 44% to 74%, while the erythemal index decreased from 0.391 [llogo.hu]

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Nodular Malignant Melanoma

RCM features of nodular melanoma show atrophic or thin epidermis, sheet-like structures at the dermo-epidermal junction and the presence of single or variable-in-size clusters [clinicaldermatology.eu]

Skin is thin, about 4-5 cell layers thick, which is often related to aging. Histological features include epidermal atrophy and increased number of melanocytes. [en.wikipedia.org]

[…] atrophic or thin epidermis commonly spared by RCM pagetoid cells or limited to few cells focally distributed; 2) dermo-epidermal junction destroyed with pleomorphic cells [clinicaldermatology.eu]

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Vasculitis

Cornoid lamellae are the characteristic feature of porokeratosis and some rare forms of epidermal naevi. [dermnetnz.org]

Cyst A cyst is a thin walled closed capsule or sac like structure, filled with fluid, solid or semisolid material. Cysts have an epithelial lining. [dermnetnz.org]

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Pilonidal Cyst

epidermal cover that is easily breakable. [ejs.eg.net]

[…] natal cleft in contrast to open methods, in which there is a tendency for the healing wound edges to be drawn inward by fibrosis, recreating a deep natal cleft with a broad thin [ejs.eg.net]

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