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104 Possible Causes for Episodic Acute Liver Failure

  • Wolcott-Rallison Syndrome

    liver failure, or pancytopenia, diabetes associated with skeletal dysplasia, short stature, episodes of acute liver failure, or pancytopenia.[abstracts.eurospe.org] WRS should be suspected in any infant who presents with permanent neonatal diabetes associated with skeletal dysplasia and/or episodes of acute liver failure.[ncbi.nlm.nih.gov] A 10-year-old Arabic boy of consanguineous parents has suffered eight episodes of acute liver failure with haemolysis triggered by intercurrent febrile illnesses.[ncbi.nlm.nih.gov]

  • Alcoholic Liver Disease

    However, acute episodes of liver failure may be induced by episodes of AH or complications of portal hypertension such as variceal bleeding.[ceaccp.oxfordjournals.org]

  • Cholestasis

    Additionally, the liver biopsy did not have any of the hepatocyte loss, inflammation, or necrosis typically associated with acute liver failure, or any cirrhosis or fibrosis[pediatrics.aappublications.org] For instance, hepatic siderosis has been documented in cases of neonatal acute liver failure. 14 Our patient’s history of coagulopathy, transaminitis, and direct hyperbilirubinemia[pediatrics.aappublications.org] […] during his early hypotensive shock episode indicate that he likely suffered at least acute hepatic injury; however, his coagulopathy quickly improved and he never developed[pediatrics.aappublications.org]

  • Torsades De Pointes

    Acute kidney injury, liver failure. Metabolic; hypothyroidism, anorexia nervosa, malnutrition. Bradycardia; sinoatrial disease, atrioventricular (AV) block.[patient.info] Acute kidney injury , liver failure . Metabolic; hypothyroidism , anorexia nervosa , malnutrition . Bradycardia; sinoatrial disease, atrioventricular (AV) block.[patient.info] Presentation Episodes of torsades in patients with congenital long QT syndromes may be triggered by stress, fear or physical exertion.[patient.info]

  • Acute Liver Failure

    […] to be associated with recurrent acute-liver-failure in children.[ncbi.nlm.nih.gov] liver failure when standard testing is inconclusive.[ncbi.nlm.nih.gov] He then went on to suffer another episode of acute-liver-failure with multi-organ failure, necessitating an urgent liver transplant.[ncbi.nlm.nih.gov]

  • Combined Oxidative Phosphorylation Defect Type 14

    episodes, elevated plasma C8–C18 acylcarnitine esters Clinical features: Episodic acute liver failure, hyperammonemia, encephalopathy Treatment: Liver transplantation Carnitine[merckmanuals.com] […] profile: Similar to LCHAD deficiency Clinical features: Liver failure, cardiomyopathy, fasting hypoglycemia, myopathy, sudden death Treatment: Similar to that for LCHAD deficiency[merckmanuals.com] […] cardiomyopathy, developmental delay Treatment: L-Carnitine Long-chain fatty acid transport deficiency (603376) — — Biochemical profile: Low to normal free carnitine; during acute[merckmanuals.com]

  • Hemophilia

    Ljung Pediatric Drugs (2018) The effects of intraoperative cryoprecipitate transfusion on acute renal failure following orthotropic liver transplantation Shuang Liu, Xiaoliang[doi.org] PAPPENHAGEN in: Further reading Prevention and Management of Bleeding Episodes in Children with Hemophilia Rolf C. R.[doi.org]

  • Secondary Sclerosing Cholangitis

    At present, the remaining three patients (patient Nos 2, 6, and 8) are still in a relatively stable condition without acute signs of liver failure.[gut.bmj.com] Patient No 3 has been registered in our transplant programme due to deteriorating liver function and several episodes of oesophageal variceal bleeding.[gut.bmj.com]

  • Hepatic Encephalopathy

    Among the potential co-factors in people with acute liver failure: Excessive alcohol use Kidney failure Constipation, which increases the intestinal production of ammonia[verywell.com] […] and minimal Type Nomenclature Subcategories A Encephalopathy associated with acute liver failure B Encephalopathy associated with portal-systemic bypass and no intrinsic[doi.org] Many of these factors have nothing to do with either the liver or the brain; they simply appear to either trigger an attack or further aggravate an existing episode.[verywell.com]

  • Liver Failure

    One patient died of multiple organ failure. Of the 7 patients that survived the acute episode, all were alive and well up to age 14 years.[omim.org] Clinical and biochemical improvement began after 2 to 3 weeks of supportive care, and liver functions returned to normal within 3 to 4 months; however, liver size normalized[omim.org] During the acute phase, liver biopsy of 2 patients showed minimal chronic inflammation and mild focal proliferation of bile ductules, with variable portal and sinusoidal fibrosis[omim.org]

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