Episodic Facial Swelling & Headache & Hoarseness: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Episodic Facial Swelling, Headache, Hoarseness,

Negated

None

Unsure

None

Possible Causes

Hereditary Angioedema Type 3

All impeded androgens have many potentially important side effects, including masculinization, headaches, lack of libido or increased libido, hair gain or loss, liver function [clinicaladvisor.com]

In this context one or more episodes of isolated angioedema may occur, mostly as a facial swelling. [aacijournal.biomedcentral.com]

[…] of swollen and painful legs, flatulence, palpebral and labial edema, dyspnea, dysuria, frequent herpetic infections of mouth and nose, subfebrile body temperature and was hoarse [signavitae.com]

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Angioedema

The most common adverse drug reactions are injection site reactions, upper respiratory infections, headache, rash, muscle pain, dizziness, and diarrhea. [medscape.com]

Six months later, the patient had an episode of bilateral facial swelling, lip swelling, and difficulty breathing. [hoajonline.com]

[…] face, lips, tongue, or other parts of the body More severe symptoms may include: Trouble swallowing, or feeling like your throat is closing Trouble breathing or wheezing Hoarse [fairview.org]

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Hereditary Angioedema

Severities were aggravated by activity and his headache had shown recent progression with abdominal pain. [ncbi.nlm.nih.gov]

The patient reports several episodes of mild facial swelling that occurred during childhood between the ages of 5-18, but he does not recall seeing a physician or receiving [step1.medbullets.com]

Symptoms include: Airway blockage -- involves throat swelling and sudden hoarseness Repeat episodes of abdominal cramping without obvious cause Swelling in the hands, arms [nlm.nih.gov]

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Systemic Scleroderma

TMD symptoms (muscle pain on chewing, difficulty in mouth opening, headaches) were complained by 92.5% of SSc patients and by 76.2% of controls (χ² 8.012 p 0.005). [ncbi.nlm.nih.gov]

Increasingly severe episodes of RP, recurrent digital swelling and gastro-oesophageal reflux were also reported. [rheumatology.oxfordjournals.org]

Headaches, depression, and anxiety. It can also lead to tiredness, weight loss and loss of appetite. Cardiac Shortness of breath due to heart problems. [sclerodermasociety.co.uk]

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Carotid Artery Aneurysm

Subarachnoid hemorrhage usually causes photophobia, intense headache, meningismus signs or fainting. [symptoma.com]

Episodes of transient blindness, syncope, swelling neck and pulsating tinnitus may also occur. [patient.info]

A 44-year-old female was admitted with hoarseness and swallowing disorders. [ncbi.nlm.nih.gov]

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Bacterial Tracheitis

[…] stridor: A high pitched crowing sound that is heard, while the child breathes in Scratchy feeling in the throat, hoarse voice Fever Chest pain, difficulty breathing Ear ache Headache [dovemed.com]

swelling history of similar episodes May have positive family history Laryngeal foreign body Absent Croupy Dysphonia Present History of aspiration Very acute presentation [ncbi.nlm.nih.gov]

A previously healthy young adult presented with inspiratory stridor and hoarseness but minimal dysphagia. [ncbi.nlm.nih.gov]

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Laryngeal Edema

Symptoms include: Mouth breathing Nasal obstruction Reduced or complete loss of sense of smell Runny nose Headaches or pain are NOT common unless there is also a sinus infection [authorstream.com]

In patients with HAE, dental surgery--including tooth extraction--may be followed by self-limiting edema episodes, including lip swelling, facial swelling, tongue edema and [ncbi.nlm.nih.gov]

We here describe two cases whose only symptoms were hoarseness and in which inspection revealed laryngeal edema when the patients ingested any of these substances. [ncbi.nlm.nih.gov]

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Migraine

What is a migraine headache? A migraine headache is a type of headache that tends to recur in an individual and causes moderate to severe pain. [my.clevelandclinic.org]

There is usually tenderness and swelling over the carotid artery in the neck. Episodes can occur several times weekly and last a few minutes to hours. [healthcommunities.com]

[…] areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness [botoxchronicmigraine.com]

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Carotid Artery Dissection

A 56-year-old man presented for evaluation of right-sided headache and pain behind his right eye. [mdedge.com]

Episodes of transient blindness, syncope, swelling neck and pulsating tinnitus may also occur. [patient.info]

A 57-year old man visited our hospital complaining of dysphagia and hoarseness lasting for two weeks. [ncbi.nlm.nih.gov]

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Mucopolysaccharidosis

She was 12 years old and had refractory headaches. [ncbi.nlm.nih.gov]

Patient 8 had one episode of facial swelling without urticaria during the infusion at week 47. [nejm.org]

Vocal cords can also enlarge, resulting in a deep, hoarse voice. [youtube.com]

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Mucopolysaccharidosis 2

Pressure from these fluids can cause other problems that may cause severe headaches, interfere with vision and change your child's mental state. [mayoclinic.org]

Symptoms included nodular soft-tissue masses located around joints, with episodes of painful swelling of the masses and pain that ended spontaneously within 3 days. [en.wikipedia.org]

Common signs and symptoms include a large head, full lips, large rounded cheeks, a broad nose, hoarse voice and an enlarged tongue (macroglossia). [symptoma.com]

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Vertebral Artery Aneurysm

The headache and aneurysm were both right sided suggesting a possible relationship. [ncbi.nlm.nih.gov]

Episodes of transient blindness, syncope, swelling neck and pulsating tinnitus may also occur. [patient.info]

The patient was discharged with slight hoarseness and dysphasia 5 weeks after surgery. She had only slight hoarseness at 6 months. [ncbi.nlm.nih.gov]

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Internal Carotid Artery Aneurysm

A 59-year-old patient presented with a four-year history of chronic oral pain accompanied by a right-sided occipital headache. [ncbi.nlm.nih.gov]

Episodes of transient blindness, syncope, swelling neck and pulsating tinnitus may also occur. [patient.info]

A 44-year-old female was admitted with hoarseness and swallowing disorders. [ncbi.nlm.nih.gov]

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Mucopolysaccharidosis 1

Presence of acute behavioral changes, headaches, and vomiting should trigger an evaluation of hydrocephalus. [medicalhomeportal.org]

Symptoms included nodular soft-tissue masses located around joints, with episodes of painful swelling of the masses and pain that ended spontaneously within 3 days. [en.wikipedia.org]

Vocal cords can also enlarge, resulting in a deep, hoarse voice. [ghr.nlm.nih.gov]

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Orthostatic Intolerance due to NET Deficiency

headaches. [web.archive.org]

Two weeks after the second injection she began to experience a “flu-like” episode that continued for about a week and was followed by facial swelling, streptococcal infection [hormonesmatter.com]

Rehydration therapy was continued with the home TPN formulation; however, she developed encephalopathy, generalized tremors, aphonia (hoarseness), progressive hyperglycemia [cdc.gov]

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Traumatic Pneumocephalus

Headache Classification Committee of the International Headache Society. [cambridge.org]

He reported a right sided facial swelling and pain following a mid-air collision with another player two hours earlier. [intjem.springeropen.com]

[…] neurosis【戦争神経症】(combat neurosis) *Warthin tumor【ワルシン腫瘍】(adenolymphoma) *water intoxication【水中毒】 *weakness【衰弱】 *wet beriberi【湿性脚気】 *wet gangrene【湿性壊疽】(moist gangrene) *wet hoarseness [medo.jp]

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Congenital Hypothyroidism

After thyroxine treatment, she also had headache, vomiting, and palpitation, lack of appetite, and sleep disturbance. [ncbi.nlm.nih.gov]

Cool and pale skin Difficult breathing Wide, short hands Reduced activities Dry and brittle hair Swelling around eyes Coarse facial features Thick protruding tongue Goiter [hxbenefit.com]

The child may also have: Poor feeding, choking episodes Constipation Dry, brittle hair Hoarse cry Jaundice (skin and whites of the eyes look yellow) Lack of muscle tone [mountsinai.org]

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Neurilemmoma

She also complained of headaches but had no other features of raised intracranial pressure. [jnnp.bmj.com]

A physical examination revealed normal soft tissue of the oral cavity, and no facial swelling, percussion pain, or mobility of the molar teeth in the right mandible was noted [ajnr.org]

The patient’s cough resolved postoperatively; however, he developed hoarseness following surgery. [thenerve.net]

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Exercise-Induced Anaphylaxis

He started having a headache simultaneously. [jpharmacol.com]

She had been seen in the Emergency Department with facial swelling and urticaria, and was treated with hydrocortisone and chlorpheniramine. [onlinelibrary.wiley.com]

More severe symptoms include swollen tongue, hoarse voice, difficulty swallowing, noisy breathing, wheezing, persistent cough, and feeling faint or weak. [foodallergycanada.ca]

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Chronic Abscess

No surgery was performed, and the patient continued to have episodic facial swelling with a variable response to antibiotics. [ajnr.org]

In laryngitis there are few visible signs of infection but with soreness lower down the throat often associated with a hoarse voice. [patient.info]

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Familial Recurrent Peripheral Facial Palsy

Familial Mediterrenean fever is a common disease in the Turkish population but neurological involvement such as headache, myalgia, demyelinationg lesions, aseptic meningitis [jpedres.org]

Melkersson-Rosenthal is characterized by facial paralysis, episodic facial swelling, and a fissured tongue (scrotal tongue or lingua plicata) and typically begins in adolescence [ispub.com]

[…] spastic paraplegia type 8 Autosomal dominant spastic paraplegia type 9 Autosomal dominant striatal neurodegeneration Autosomal recessive Charcot-Marie-Tooth disease with hoarseness [se-atlas.de]

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Lower Extremity Arterial Aneurysm

Clinical Indications : Shoulder/arm numbness and tingling Pain Fatigue Clumsiness Weakness Headache Continuous wave Doppler is used to take segmental pressures of the upper [pacificvascular.com]

Episodes of transient blindness, syncope, swelling neck and pulsating tinnitus may also occur. [patient.info]

Relevant comorbidities (most relevant): Smoking Advanced age Thoracic aortic aneurysm History: Chest, upper back, neck and/or jaw pain Coughing, hoarseness or trouble breathing [clinicaladvisor.com]

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ACE Inhibitor-Induced Angioedema

Head: swelling of the eyelids, lips, facial skin, headaches, dizziness Genital organs: swelling of the external genital organs Arms and legs: swellings on hands, feet, arms [aha.ch]

Six months later, the patient had an episode of bilateral facial swelling, lip swelling, and difficulty breathing. [hoajonline.com]

However, when there is oedema around the head and neck, observation to detect airway involvement is required (for example, hoarseness). [patient.info]

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Lethal Midline Granuloma

Your headache and occasional nosebleed are probably just a sinus infection, so don't lose any sleep over this one. [hypochondriacheaven.com]

Initially, the swelling cnetrofacial soft and comes and goes, with each episode lasting weeks or months. [free-reprint-articles.com]

The patient was referred to our hospital because of long-lasting hoarseness. He was treated for granuloma laryngis. [ncbi.nlm.nih.gov]

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Pathological Fracture

A 72-year-old man was admitted to our clinic with a 5-month history of occipital headache. [ncbi.nlm.nih.gov]

episodes. [ncbi.nlm.nih.gov]

[…] get emergency medical treatment: rash hives itching difficulty breathing or swallowing swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs hoarseness [medlineplus.gov]

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Ophthalmoplegic Migraine

Recurrent painful ophthalmoplegic neuropathy (RPON), formerly named ophthalmoplegic migraine (OM), is a rare condition characterized by the association of unilateral headaches [ncbi.nlm.nih.gov]

There is usually tenderness and swelling over the carotid artery in the neck. Episodes can occur several times weekly and last a few minutes to hours. [healthcommunities.com]

足間代 Friedreich's ataxiaフリートライヒ［運動］失調症 g gag reflex絞扼反射、咽頭反射 gait disturbance歩行障害 grand mal大発作 Guillain-Barré syndromeギラン－バレー症候群 h hemiballism片［半］側バリズム hemiplegia片麻痺、半側麻痺 hoarseness [tokyo-med.ac.jp]

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Splenic Artery Aneurysm

—In the past six to eight years, she had suffered from headache with nausea, occasional vomiting, bloating, and full sensation under the left costal margin which was associated [jamanetwork.com]

Episodes of transient blindness, syncope, swelling neck and pulsating tinnitus may also occur. [patient.info]

These aneurysms may cause a pulsating sensation, distal ischemic symptoms, stroke, local pain, transient ischemic attacks, and hoarseness. [healthguideinfo.com]

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Mucopolysaccharidosis 4

The most common side effects reported during Vimizim infusions included fever, vomiting, headache, nausea, abdominal pain, chills, and fatigue. [biomarin.com]

Symptoms included nodular soft-tissue masses located around joints, with episodes of painful swelling of the masses and pain that ended spontaneously within 3 days. [en.wikipedia.org]

[…] deformity, dorsolumbar kyphosis, increased anteroposterior diameter of chest, pectus excarinatum, waddling gait, pot belly, valgus deformity of both upper and lower limbs and hoarse [apicareonline.com]

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Erythema Marginatum

Often there are also systemic symptoms, including chills, fever, headache, vomiting, backache, and stiff neck. [medical-dictionary.thefreedictionary.com]

[…] pain or heart palpitations. » Shortness of breath. » Loss of emotional control (as manifested in sudden episodes of crying or laughing). » Jerky, sudden facial or extremities [health-benefits-of.net]

[…] effective for alleviating acute airway edema in children are generally ineffective for laryngeal HAE attacks. 20 Clinical symptoms of laryngeal edema include voice changes (eg, hoarseness [ajmc.com]

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Rapidly Progressive Glomerulonephritis

The diagnosis of PRES was based on the presence of clinical features such as headache, altered mental status, visual disturbances and seizures with positive radiological findings [ukm.pure.elsevier.com]

facial and leg swelling over the previous year. [sjkdt.org]

Nasal crusting, recurrent or persistent sinusitis, otitis media, rhinorrhea, purulent or bloody nasal discharge, and a saddle nose deformity -Respiratory symptoms include hoarseness [studyblue.com]

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