Episodic Facial Swelling & Headache & Malaise: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Episodic Facial Swelling, Headache, Malaise,

Negated

None

Unsure

None

Possible Causes

Hereditary Angioedema Type 3

All impeded androgens have many potentially important side effects, including masculinization, headaches, lack of libido or increased libido, hair gain or loss, liver function [clinicaladvisor.com]

Fatigue, malaise, irritability, hyperactivity, mood changes, and nausea are other preceding factors [ 21, 24 ]. [intechopen.com]

In this context one or more episodes of isolated angioedema may occur, mostly as a facial swelling. [aacijournal.biomedcentral.com]

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Erysipelas

Also, at the same time general malaise, headache, sickness and an urge to vomit are present. [en.dermatim.net]

Fever with chills and general malaise may be prominent symptoms. Antibiotics are usually effective. Patients handled in a timely manner tend to recover without problems. [ncbi.nlm.nih.gov]

6. regional lymph node swelling and tenderness 7. [slideshare.net]

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Angioedema

The most common adverse drug reactions are injection site reactions, upper respiratory infections, headache, rash, muscle pain, dizziness, and diarrhea. [medscape.com]

Hereditary angioedema attacks are often preceded by a prodrome, such as fatigue, malaise, mood changes, joint or muscle pain, nausea, thirst or erythema marginatum; the latter [magonlinelibrary.com]

Six months later, the patient had an episode of bilateral facial swelling, lip swelling, and difficulty breathing. [hoajonline.com]

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Hereditary Angioedema

Severities were aggravated by activity and his headache had shown recent progression with abdominal pain. [ncbi.nlm.nih.gov]

Fatigue, malaise, irritability, hyperactivity, mood changes, and nausea are other preceding factors [ 21, 24 ]. [intechopen.com]

The patient reports several episodes of mild facial swelling that occurred during childhood between the ages of 5-18, but he does not recall seeing a physician or receiving [step1.medbullets.com]

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Coxsackievirus Infection

Stiff neck, headache, and pain related to bright lights (photophobia) are signs of meningitis. [healthychildren.org]

The disease begins with a mild fever, poor appetite, malaise and frequently a sore throat. One or 2 days after the fever begins, painful sores develop in the mouth. [histopathology-india.net]

She denied any chest pain, facial or leg swelling, weakness, headache, or dizziness. [hindawi.com]

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Migraine

What is a migraine headache? A migraine headache is a type of headache that tends to recur in an individual and causes moderate to severe pain. [my.clevelandclinic.org]

Systemic symptoms like myalgia, fever, malaise or weight loss. Described as the worst headache of the patient's life, especially if it was rapid in onset. [patient.info]

There is usually tenderness and swelling over the carotid artery in the neck. Episodes can occur several times weekly and last a few minutes to hours. [healthcommunities.com]

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Neck Pain

A 32-year-old Chinese woman sought care from our family medicine clinic because she had a headache, neck pain, and an intermittent cough that had produced white sputum for [ncbi.nlm.nih.gov]

Suggest cancer, infection, or inflammation: Malaise, fever, unexplained weight loss. Pain that is increasing, is unremitting, or disturbs sleep. [patient.info]

We presented a case of a 69-year-old woman who experienced monthly episodes of facial swelling and nonpruritic, erythematous rash on her face, accompanied by high fever, nausea [ncbi.nlm.nih.gov]

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Systemic Scleroderma

TMD symptoms (muscle pain on chewing, difficulty in mouth opening, headaches) were complained by 92.5% of SSc patients and by 76.2% of controls (χ² 8.012 p 0.005). [ncbi.nlm.nih.gov]

Abstract Scleroderma renal crisis (SRC) occurs in 5–10% of SSc patients, who may present with an abrupt onset of hypertension, acute renal failure, headaches, fevers, malaise [doi.org]

Increasingly severe episodes of RP, recurrent digital swelling and gastro-oesophageal reflux were also reported. [rheumatology.oxfordjournals.org]

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Lethal Midline Granuloma

Your headache and occasional nosebleed are probably just a sinus infection, so don't lose any sleep over this one. [hypochondriacheaven.com]

May extend into sinuses but does not primarily involve them Marrow and nodes involved only if disseminated Other sites Skin, soft tissue, GI tract, testis May have fever, malaise [surgpathcriteria.stanford.edu]

Initially, the swelling cnetrofacial soft and comes and goes, with each episode lasting weeks or months. [free-reprint-articles.com]

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Orthostatic Intolerance due to NET Deficiency

headaches. [web.archive.org]

[…] symptoms usually develop suddenly and can include: Swelling in one or both testicles Pain ranging from mild to severe Fever Nausea and vomiting General feeling of unwellness (malaise [mayoclinic.org]

Two weeks after the second injection she began to experience a “flu-like” episode that continued for about a week and was followed by facial swelling, streptococcal infection [hormonesmatter.com]

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Chronic Abscess

Malaise 3. Fever, drowsiness 4. Neck rigidity with Kernig's sign positive. 5. [specialist-ent.com]

No surgery was performed, and the patient continued to have episodic facial swelling with a variable response to antibiotics. [ajnr.org]

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Traumatic Pneumocephalus

Headache Classification Committee of the International Headache Society. [cambridge.org]

A 23 year 2004; 44:218–19. old woman with malaise, anorexia, fever and behavior 242 D’Angelo VA, Monte V, Scialfa G, Fiumara E, Scotti G. changes]. [pubhtml5.com]

He reported a right sided facial swelling and pain following a mid-air collision with another player two hours earlier. [intjem.springeropen.com]

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Rosacea

The ... read more Cluster Headaches: Painful but Treatable, Preventable Nov. 18, 2016 — Often called the suicide headache because of the excruciating intensity of the pain [sciencedaily.com]

She was otherwise healthy, with no history of fever, malaise, or weight loss. [ncbi.nlm.nih.gov]

Rosacea can develop gradually, as mild episodes of facial blushing. Over time, flushing may lead to a permanently red face. [laserandskin.ie]

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Facial Nerve Paralysis of the Newborn

[…] paroxysmal hemicrania) 만성 송이두통(Chronic cluster headache)) 우발성 송이 두통(Episodic cluster headache) G44.1 달리 분류되지 않은 혈관성 두통(Vascular headache, NEC) 혈관성 두통(Vascular headache) NOS [dic.impact.pe.kr]

[…] initial symptoms are fever, fatigue, headache, vomiting, stiffness in the neck, and pain in the limbs. et nõukogu määrus (EÜ) nr # (puu-ja köögivili en from mild fever and malaise [et.glosbe.com]

Melkersson-Rosenthal Syndrome  Acute episodes of facial paralysis  Facial swelling  Fissured tongue  Very rare  Familial but sporadic  Usually begins in adolescence [slideshare.net]

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Holmes-Adie Syndrome

She abandoned treatment after developing headache as a side effect of the drug. [scielo.br]

A fixed oval pupil, in association with severe pain, a red eye, a cloudy cornea and systemic malaise, suggests acute angle-closure glaucoma. [patient.info]

Depending on the area of swelling, pain can be absent or mild, as in most peripheral or facial swelling, or it can be very severe, as in gastrointestinal angioedema. [intranet.tdmu.edu.ua]

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Familial Recurrent Peripheral Facial Palsy

Familial Mediterrenean fever is a common disease in the Turkish population but neurological involvement such as headache, myalgia, demyelinationg lesions, aseptic meningitis [jpedres.org]

Symptoms after a tick bite include headache, malaise, myalgias, chills and fever, nausea and vomiting, and neurologic sequelae. [ispub.com]

There was no history of trauma, headache or motor weakness in extremities. There was no history of ear discharge, ear pain, tinnitus or vertigo. [bhj.org.in]

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Erythema Marginatum

Often there are also systemic symptoms, including chills, fever, headache, vomiting, backache, and stiff neck. [medical-dictionary.thefreedictionary.com]

The most prevalent other prodromal symptoms were other skin symptoms, malaise, psychological changes, fatigue and gastrointestinal symptoms. [ncbi.nlm.nih.gov]

[…] pain or heart palpitations. » Shortness of breath. » Loss of emotional control (as manifested in sudden episodes of crying or laughing). » Jerky, sudden facial or extremities [health-benefits-of.net]

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Laryngeal Edema

Symptoms include: Mouth breathing Nasal obstruction Reduced or complete loss of sense of smell Runny nose Headaches or pain are NOT common unless there is also a sinus infection [authorstream.com]

Fever, malaise, dysphagia, and throat pain may occur in more severe infections. Laryngeal edema, although rare, may cause stridor and dyspnea. [merckmanuals.com]

In patients with HAE, dental surgery--including tooth extraction--may be followed by self-limiting edema episodes, including lip swelling, facial swelling, tongue edema and [ncbi.nlm.nih.gov]

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Bacterial Tracheitis

[…] stridor: A high pitched crowing sound that is heard, while the child breathes in Scratchy feeling in the throat, hoarse voice Fever Chest pain, difficulty breathing Ear ache Headache [dovemed.com]

[…] intravenous monotherapy with ceftriaxone (Rocephin), cefotaxime (Claforan), or ampicillin/sulbactam (Unasyn) 13 – 15 Influenza Abrupt onset of fever, headache, myalgia, malaise [aafp.org]

swelling history of similar episodes May have positive family history Laryngeal foreign body Absent Croupy Dysphonia Present History of aspiration Very acute presentation [ncbi.nlm.nih.gov]

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Exercise-Induced Anaphylaxis

He started having a headache simultaneously. [jpharmacol.com]

She had been seen in the Emergency Department with facial swelling and urticaria, and was treated with hydrocortisone and chlorpheniramine. [onlinelibrary.wiley.com]

Late sequelae included frontal headaches that persisted for 24-72 hours. (See Clinical Presentation.) [emedicine.medscape.com]

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Lower Extremity Arterial Aneurysm

Clinical Indications : Shoulder/arm numbness and tingling Pain Fatigue Clumsiness Weakness Headache Continuous wave Doppler is used to take segmental pressures of the upper [pacificvascular.com]

Infectious aneurysms may cause local pain, fever, malaise, and weight loss. Diagnosis is by ultrasonography, magnetic resonance angiography, or CT. [merckmanuals.com]

Episodes of transient blindness, syncope, swelling neck and pulsating tinnitus may also occur. [patient.info]

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Splenic Artery Aneurysm

—In the past six to eight years, she had suffered from headache with nausea, occasional vomiting, bloating, and full sensation under the left costal margin which was associated [jamanetwork.com]

Inflammatory or mycotic aneurysms may cause the symptoms of a systemic infection, such as weight loss, fever, and malaise, and it may also cause local pain. [healthguideinfo.com]

Episodes of transient blindness, syncope, swelling neck and pulsating tinnitus may also occur. [patient.info]

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Ophthalmoplegic Migraine

Recurrent painful ophthalmoplegic neuropathy (RPON), formerly named ophthalmoplegic migraine (OM), is a rare condition characterized by the association of unilateral headaches [ncbi.nlm.nih.gov]

Systemic symptoms like myalgia, fever, malaise or weight loss. Described as the worst headache of the patient's life, especially if it was rapid in onset. [patient.info]

There is usually tenderness and swelling over the carotid artery in the neck. Episodes can occur several times weekly and last a few minutes to hours. [healthcommunities.com]

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Rapidly Progressive Glomerulonephritis

The diagnosis of PRES was based on the presence of clinical features such as headache, altered mental status, visual disturbances and seizures with positive radiological findings [ukm.pure.elsevier.com]

fever, body aches, loss of appetite, chills, weight loss, malaise). [symptoma.com]

facial and leg swelling over the previous year. [sjkdt.org]

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Abdominal Pregnancy

She presented to Felegehiwot Referal Hospital with a principal complaint of vomiting, epigastric pain, headache, and blurring of vision. [ncbi.nlm.nih.gov]

[…] persistent pain, either in the abdomen or in the suprapubic area, nausea, vomiting, painful movements of the fetus, regular menstruation cycles, vaginal discharge (bloody), and malaise [symptoma.com]

Symptoms of preeclampsia include nausea, upper abdominal pain, facial swelling and distorted vision. HELLP Syndrome. [newkidscenter.com]

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Erythropoietic Protoporphyria

Commonly occurring adverse reactions included headache and implant-site reactions. [ncbi.nlm.nih.gov]

A 27-year-old man bearing an erythropoietic protoporphyria (EPP)-associated ferrochelatase (FECH) mutation was admitted to our hospital for general malaise and marked elevation [ncbi.nlm.nih.gov]

However, the patient’s father reported a prior history of “recurrent” episodes of hand and facial swelling that also seemed to occur from prolonged exposure to sunlight and [jcadonline.com]

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Pauci-Immune Glomerulonephritis

She had an extensive hospital stay and developed nonoliguric acute kidney injury (AKI) 1 day after a head CT with contrast was performed because she was experiencing headaches [karger.com]

We present the case of a 48-year-old male smoker, who started with malaise and the blood chemistry ( Table 1 ) showed a reduction of renal function (creatinine [Cr]: 1.8 mg [revistanefrologia.com]

In October 2013, she was noted to have progressive bilateral lower limb swelling and facial puffiness. She also reported frothy urine but no gross haematuria. [hkmj.org]

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Sialolithiasis

Individuals with viral infection such as mumps will present acutely with pain and swelling of both salivary glands, associated with the viral prodrome fever, malaise, headache [teachmesurgery.com]

swelling over one or two days. [journals.lww.com]

Children typically present with recurrent episodes of acute or subacute parotid gland swelling with fever, malaise, and pain ( Figure 3 ). [aafp.org]

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Cheilitis

This kind of cracked lips presents with other associated symptoms such as headache, fever, and mild lymph node enlargement. [medindia.net]

Patients can have associated generalised, nonspecific symptoms that should prompt further investigation (e.g. malaise, weight loss, loss of appetite and night sweats), but [medicinetoday.com.au]

[8][9] Labial swelling is initially characterized by recurrent edematous swellings mimicking angioedema, subsequently after many episodes, it becomes persistent and indurated [ncbi.nlm.nih.gov]

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Lip Disease

There can also be fever, headaches, and paralysis of the facial muscles. Cheilitis glandularis only affects the lower lip. [steadyhealth.com]

Sarcoidosis A multisystem granulomatous disorder, the common manifestations include dyspnea, dry cough, chest pain, fever, malaise, fatigue, arthralgia and weight loss. [jcda.ca]

She had never experienced similar episodes in the past. [ncbi.nlm.nih.gov]

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