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382 Possible Causes for Epistaxis, Hematemesis

  • Wiskott Aldrich Syndrome

    Wiskott-Aldrich syndrome (WAS) is a rare immunodeficiency disease with a characteristic phenotype that includes: X-linked recessive petechiae, bloody diarrhoea, epistaxis[radiopaedia.org] The clinical presentation of WAS includes several key findings: Bleeding abnormalities - As a result of thrombocytopenia, petechiae, epistaxis, hematemesis and melena are[symptoma.com] Further questioning reveals a past medical history of multiple hospital stays due to pneumonia and otitis media infections as well as recurrent epistaxis.[step1.medbullets.com]

  • Bleeding Diathesis

    Correction of the bleeding diathesis to control the epistaxis required treatment of the tumour with chemotherapy.[ncbi.nlm.nih.gov] Signs: Abnormal Bleeding (multiple sites) Nasopharynx Epistaxis Bleeding Gums Gastrointestinal Hematemesis Melana Gynecologic Menorrhagia Postpartum Hemorrhage Musculoskeletal[fpnotebook.com] The patient reported that this was the third episode of hematemesis in one day.[cureus.com]

  • Hemophilia B

    Bleeding into muscle, soft tissue or joints (hemarthrosis), GI / GU tract bleeding, easy bruising, excessive bleeding after surgery, trauma, dental procedures or circumcision; epistaxis[pathologyoutlines.com] Tingling, cracking, warmth, pain, stiffness, and refusal to use joint (children) CNS - Headache, stiff neck, vomiting, lethargy, irritability, and spinal cord syndromes GI - Hematemesis[emedicine.medscape.com] Other common symptoms include excessive bruising, oral bleeding, epistaxis, hematuria, rectal bleeding, weakness, abdominal pain and tenderness, dyspnea and headache.[symptoma.com]

  • Disseminated Intravascular Coagulation

    Clinical history can include epistaxis, gingival bleeding, haematuria, oliguria, cough, dyspnoea, fever, delirium, and coma.[bestpractice.bmj.com] References: [3] [4] Clinical features Bleeding manifestations Petechiae , purpura , ecchymoses Oozing of blood from surgical wounds, intravenous lines Hematuria Hematemesis[amboss.com] […] pathways Activation and/or impairment of fibrinolysis Clinical Presentation Generally occurs in the setting of a risk factor listed above Hemorrhage – petechiae, purpura, epistaxis[arupconsult.com]

  • Factor VII Deficiency

    FVIID was diagnosed for the first time in a 23-year-old pregnant woman at the 24th week of gestation due to complaint of intermittent epistaxis.[ncbi.nlm.nih.gov] Bleeding isolated to a single organ or system (eg, hematuria, hematemesis, hemoptysis) is less likely to be due to a hemostatic abnormality than to a local cause such as neoplasm[emedicine.medscape.com] One-day replacement therapy resulted in very favourable outcomes in haemarthroses, and was successful in muscle/subcutaneous haematomas, epistaxis and gum bleeding.[ncbi.nlm.nih.gov]

  • Warfarin

    The following day his INR rebounded to 8.5 and he suffered a spontaneous epistaxis requiring readmission; he was treated with low titrated doses of vitamin K1.[ncbi.nlm.nih.gov] ., intracranial hemorrhage, gastrointestinal (GI) bleed, hematemesis, intraocular bleeding, hemarthrosis) can occur at virtually any site on the body.[ncbi.nlm.nih.gov] The most frequently reported events were: increased international normalised ratio (INR, 111 reports); contusion (21); haematuria (17); and epistaxis (8).[gov.uk]

  • Hemophilia A

    Menorrhagia was predominant (13.6%) followed by epistaxis (9%), gingivorrhagia (9%), and prolonged bleeding after tooth extraction (9%).[ncbi.nlm.nih.gov] […] refusal to use the joint (young children) Central nervous system (CNS) - Headache, stiff neck, vomiting, lethargy, irritability, spinal cord syndromes Gastrointestinal (GI) - Hematemesis[emedicine.medscape.com] Bleeding into muscle, soft tissue or joints (hemarthrosis), GI / GU tract bleeding, easy bruising, excessive bleeding after surgery, trauma, dental procedures or circumcision; epistaxis[pathologyoutlines.com]

  • Hemophilia

    Menorrhagia was predominant (13.6%) followed by epistaxis (9%), gingivorrhagia (9%), and prolonged bleeding after tooth extraction (9%).[ncbi.nlm.nih.gov] […] involvement include: • Fever • Abdominal distention and pain • Melena (bloody stool) • Hip flexion contracture (iliopsoas muscle spasm due to retroperitoneal hemorrhage) • Hematemesis[physio-pedia.com] Several episodes of frequently occurring bleeding from gums, nose (epistaxis), etc and easy bruising are characteristic findings.[symptoma.com]

  • Hereditary Hemorrhagic Telangiectasia

    PROBLEM/OBJECTIVES: Epistaxis is the most common manifestation of hereditary hemorrhagic telangiectasia (HHT); it is present in 90% of HHT patients 45 years old.[ncbi.nlm.nih.gov] […] granulomatosis with polyangiitis, Goodpasture’s disease), lung trauma, pulmonary embolus, cardiac causes (mitral stenosis, left ventricular failure), and spurious (epistaxis, hematemesis[clinicaladvisor.com] Recurrent, spontaneous epistaxis is the most common presenting symptom.[ncbi.nlm.nih.gov]

  • Glanzmann Thrombasthenia

    We present a unique case report of a 4-year-old child with known Glanzmann thrombasthenia and two separate episodes of life-threatening epistaxis that were treated successfully[ncbi.nlm.nih.gov] Unfortunately, she developed profuse bleeding at the site of G-tube insertion, followed by massive hematemesis.[learningcenter.ehaweb.org] Glanzmann thrombasthenia is a qualitative platelet function disorder manifested by skin bleeds, epistaxis, gingival bleeding, gastrointestinal hemorrhage, hematuria, hemarthrosis[ncbi.nlm.nih.gov]

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