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57 Possible Causes for Epistaxis, T-Lymphocyte Count Increased

  • Primary Immune Deficiency Disorder

    Skin infections become more common as the number of CD4 T- lymphocytes reduces. Mild reduction in CD4 T- lymphocyte count ( 200) is part of normal ageing.[dermnetnz.org] Moderate reduction in CD4 T- lymphocyte count (200-50) occurs in some elderly patients, newborn babies, and in primary immunodeficiency diseases.[dermnetnz.org] This leads to an increased incidence of herpes zoster (shingles) and in countries where it is prevalent, old-world or classic Kaposi sarcoma.[dermnetnz.org]

  • Multiple Myeloma

    Patients with a high tumor volume may present with epistaxis.[symptoma.com] Dizziness, confusion, blurred vision, headaches, epistaxis, cerebrovascular event - due to hyperviscosity.[patient.info] Serum viscosity: should be assessed if there is epistaxis, and when there are neurological symptoms or very high paraprotein levels.[patient.info]

  • Precursor-Cell Lymphoblastic Leukemia

    The increase in the ALC was primarily from activated CTL019 T lymphocytes. Patient 1 was a 7-year-old girl with a second recurrence of ALL.[doi.org] A 30-year-old pregnant woman presented at 16 weeks' gestation with epistaxis, jaundice, diffuse abdominal pain and distension, massive hepatosplenomegaly and peripheral oedema[ncbi.nlm.nih.gov] Bleeding is usually manifested by petechiae, easy bruising, epistaxis, bleeding gums, or menstrual irregularity. Hematuria and GI bleeding are uncommon.[web.archive.org]

  • Wiskott Aldrich Syndrome

    Wiskott-Aldrich syndrome (WAS) is a rare immunodeficiency disease with a characteristic phenotype that includes: X-linked recessive petechiae, bloody diarrhea, epistaxis due[radiopaedia.org] Further questioning reveals a past medical history of multiple hospital stays due to pneumonia and otitis media infections as well as recurrent epistaxis.[step1.medbullets.com] […] varicella and CMV fungal infections: Candida albicans thrombocytopenia recurrent bleeding , especially in first days of life petechiae purpura easy bruising hematemesis epistaxis[step1.medbullets.com]

  • Influenza

    Deterioration of CD4 T-lymphocyte cell counts or progression of HIV disease has not been demonstrated among HIV-infected persons after influenza vaccination compared with[cdc.gov] RESPIRATORIO R01 Dolor atribuido al aparato respiratorio R02 Fatiga respiratoria/disnea R03 Respiración jadeante/sibilante R04 Otros problemas de la respiración R05 Tos R06 Epistaxis[iqb.es] La diarrea acuosa, vómito, dolor abdominal y pleural, así como epistaxis y gingivorragia son manifestaciones comunes en los estados iniciales de la enfermedad. 19,163 Algunos[scielo.org.mx]

  • Aplastic Anemia

    CD3 T-lymphocyte ratios decreased only in the KQ group, while CD3 CD4 CD8 Tlymphocytes increased only in the KC group after 6 months (P 0.05).[ncbi.nlm.nih.gov] The patient improved symptomatically and did not have any further episodes of epistaxis or GI bleed.[jscisociety.com] Some of the types of bleeding seen in people with lthrombocytopenia include epistaxis, bleeding gums, bloodied stool and red spots in the skin.[symptoma.com]

  • Alcoholic Liver Disease

    B and T lymphocytes are noted in the portal and periportal areas, and natural killer lymphocytes are noted around hyalin-containing hepatocytes.[emedicine.medscape.com] Patients have decreased peripheral lymphocyte counts with an associated increase in the ratio of helper cells to suppressor cells, signifying that lymphocytes are involved[emedicine.medscape.com]

  • Autoimmune Thrombocytopenia

    Analysis of lymphocyte subsets revealed an increased number of CD3 gamma/delta T cells.[ncbi.nlm.nih.gov] In March 2003 the patient received high doses IVIg but during that treatment, aggravation of the haemorrhagic diathesis with epistaxis, menorrhea and secondary anaemia (Hb[springerlink.com] Treatment-related complications included transient hemorrhagic cystitis (1 patient), vaginal bleeding (2 patients), gastrointestinal bleeding (1 patient), epistaxis (1 patient[ncbi.nlm.nih.gov]

  • Myelodysplasia

    […] apoptosis of medullary B cells has also been described. 56 T-cell impairment Most patients with MDS have lymphocytopenia, mainly due to a decrease in T-helper lymphocyte[haematologica.org] Fewer than 20% of patients present with symptoms of isolated thrombocytopenia such as minor bleeding (eg, mucosal bleeding, petechiae, easy bruising, epistaxis) or major bleeding[mdedge.com] When the levels of platelets fall, petechiae, ecchymoses, epistaxis and gum bleeding may result.[symptoma.com]

  • Acute Lymphoblastic Leukemia 

    Thrombocytopenia can cause mucosal bleeding, easy bruising, petechiae/purpura, epistaxis, bleeding gums, and heavy menstrual bleeding.[msdmanuals.com] ALL is associated with a wide variety of physical examination findings, which include signs of easy bleeding (from thrombocytopenia) such as recurrent epistaxis, bruises and[cancertherapyadvisor.com] General features of acute leukemia Sudden onset of symptoms and rapid progression (days to weeks) Anemia : fatigue, pallor, weakness Thrombocytopenia : epistaxis, bleeding[amboss.com]

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