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744 Possible Causes for Epistaxis, Thrombocytopenic Purpura

  • Thrombocytopenia

    It presents in infancy or in neonates (in severe cases) with patients bruising easily along with further manifestations of thrombocytopenia including epistaxis, petechiae,[enerca.org] Abstract Thrombotic thrombocytopenic purpura (TTP) is an acute, life-threatening illness with disseminated platelet-rich thromboses of small vessels that variably presents[ncbi.nlm.nih.gov] What is immune thrombocytopenic purpura? Immune thrombocytopenic purpura (ITP) is an autoimmune disorder.[patient.info]

  • Microangiopathy

    Creatinine levels deteriorated, falling to 3.92 mg/dl (0.73 mg/dl on admission), hematocrit fell to 22.6% and thrombocytopenia to 18 000/μl, causing repeated epistaxis.[archbronconeumol.org] purpura and hemolytic uremic syndrome.[web.archive.org] The association of pregnancy with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome.[mds.marshall.edu]

  • Chronic Immune Thrombocytopenic Purpura

    The most common adverse events were headache (37%), nasopharyngitis (32%), contusion (30%), epistaxis (30%), fatigue (30%), arthralgia (25%), and diarrhea (25%).[ncbi.nlm.nih.gov] Hematuria is an uncommon manifestation of chronic immune thrombocytopenic purpura.[ncbi.nlm.nih.gov] In some instances there is oral bleeding, epistaxis, rectal bleeding or haematuria. Morbidity in ITP is usually minimal and parents need to be reassured of this.[rch.org.au]

  • Autoimmune Thrombocytopenia

    In March 2003 the patient received high doses IVIg but during that treatment, aggravation of the haemorrhagic diathesis with epistaxis, menorrhea and secondary anaemia (Hb[springerlink.com] purpura.[link.springer.com] Treatment-related complications included transient hemorrhagic cystitis (1 patient), vaginal bleeding (2 patients), gastrointestinal bleeding (1 patient), epistaxis (1 patient[ncbi.nlm.nih.gov]

  • Cerebral Thrombotic Thrombocytopenic Purpura

    […] triggers drugs (quinine, ticlopidine, clopidogrel, and cyclosporine) SLE infections AIDS malignancies Presentation Symptoms (recall pentad) thrombocytopenia easy bleeding epistaxis[medbullets.com] KEYWORDS: Cerebral microbleeds; MRI; ischemic stroke; thrombotic thrombocytopenic purpura[ncbi.nlm.nih.gov] […] headache, confusion, aphasia, transient paresis, ataxia, sensory defects and coma, as well as pallor, jaundice, fibrin thrombi in renal vessels, heart, liver and spleen, epistaxis[medical-dictionary.thefreedictionary.com]

  • Bleeding Diathesis

    Correction of the bleeding diathesis to control the epistaxis required treatment of the tumour with chemotherapy.[ncbi.nlm.nih.gov] purpura.[ncbi.nlm.nih.gov] Epistaxis is a common and difficult problem to manage in patients with bleeding disorders.[ncbi.nlm.nih.gov]

  • Disseminated Intravascular Coagulation

    […] bilateral periorbital oedema and tense orbits in keeping with orbital compartment syndrome (OCS) shortly after presenting to the emergency department for uncontrollable epistaxis[ncbi.nlm.nih.gov] We report on 3 male neonates with hereditary ADAMTS13 deficiency (Upshaw Schulman syndrome, USS), the inherited form of thrombotic thrombocytopenic purpura (TTP). 2 presented[ncbi.nlm.nih.gov] Clinical history can include epistaxis, gingival bleeding, haematuria, oliguria, cough, dyspnoea, fever, delirium, and coma.[bestpractice.bmj.com]

  • Aspirin-induced Platelet Defect

    […] defect Aggregation defect P2YR12 n/a Bernard-Soulier syndrome Adhesion disorder with deficiency or dysfunction of platelet glycoprotein Ib/IX/V complex GP1BA, GP1BB, GP9 Epistaxis[arupconsult.com] [top] Thrombotic Thrombocytopenic Purpura (TTP) and the VWF-Cleaving Protease (ADAMTS-13) Assay Thrombotic thrombocytopenic purpura (TTP) is caused by ultra-high molecular[uab.edu] ENT review did not reveal a structural cause for the epistaxis. She then had a partial response to fresh frozen plasma and cryoprecipitate.[medcraveonline.com]

  • Hypersplenism

    Prior to splenectomy the patient continued to have a marked thrombocytopenia which resulted in recurrent bouts of epistaxis; splenectomy together with tuberculostatic therapy[ncbi.nlm.nih.gov] Splenectomy is one of the primary choices of treatment in immune thrombocytopenic purpura. However, the disease may relapse despite splenectomy.[ncbi.nlm.nih.gov] In addition, symptoms such as epistaxis and gingival bleeding were ameliorated or even eliminated, and the quality of life was improved.[ncbi.nlm.nih.gov]

  • Coagulation Abnormalities

    As the platelet counts are usually 50x10 9 L -1 there is an increased incidence of bruising, epistaxis and gingival bleeding.[frca.co.uk] Cancer patients may also suffer from the impediment of hemolytic uremic syndrome or thrombotic thrombocytopenic purpura (HUS/TTP).[als-journal.com] The important thing is to rule out heparin-induced thrombocytopenia (HIT) and thrombotic thrombocytopenic purpura (TTP), two diagnoses that threaten life and limb, and are[pulmccm.org]

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