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62 Possible Causes for Eruptions, Systemic Autoinflammation

  • Erythema Nodosum

    Convert to ICD-10-CM : 695.2 converts directly to: 2015/16 ICD-10-CM L52 Erythema nodosum Clinical Information An erythematous eruption commonly associated with drug reactions[] Ahmet Gül, Behçet Disease, Textbook of Autoinflammation, 10.1007/978-3-319-98605-0_35, (647-665), (2019).[] Skin manifestations are uncommon including transient punctiform rashes, purpuric, or maculopapular eruptions. Erythema nodosum have seldom been reported.[]

  • Cryopyrin-Associated Periodic Syndrome

    Fever, limb pain, conjunctivitis, and elevation of acute phase reactants are usually associated with skin eruption.[] Hoffman, Autoinflammation: translating mechanism to therapy, Journal of Leukocyte Biology, 90, 1, (37-47), (2011). Keith A. Sikora and Alexei A.[] Antihistamines did not improve his urticaria-like eruptions.[]

  • Pyoderma

    One feature is a phenomenon known as pathergy, in which trauma to the skin can cause new eruptions of ulcers in patients with the disease.[] The dominant hypothesis is that altered innate immunity leads to systemic autoinflammation ( 5 ).[] 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes specified type of rash- code to condition vesicular eruption ( R23.8 ) pustular L08.0 ICD-10-CM Codes Adjacent[]

  • Pyoderma Gangrenosum

    A 45-year-old hypothyroid woman presented with a 6-year history of recurrent widespread eruptions of rashes and ulcers on her skin.[] OBJECTIVES: To determine a specific genetic background related to autoinflammation for PG.[] An enlarging nodule was observed over his right infraorbital area 4 months after the onset of the skin eruptions.[]

  • Muckle-Wells Syndrome

    Muckle-Wells syndrome is characterized by a recurrent urticarial eruption that is associated with episodic fever, myalgia, arthralgia, malaise, progressive sensorineural hearing[] Shinkai K, McCalmont TH, Leslie KS: Cryopyrin-associated periodic syndromes and autoinflammation. Clin Exp Dermatol 2008;33:1–9.[] Three main features of the disease are: (i) urticarial eruptions; (ii) progressive perceptive deafness; and (iii) amyloid nephropathy.[]

  • CINCA Syndrome

    The syndrome is characterized by a generalized, wandering palpable rash eruption of neonatal onset, chronic arthropathy characterized by abnormal proliferation of cartilage[] […] autoinflammatory conditions characterized by chronic systemic inflammation due to an abnormal regulation of the innate immune system.[] Three main manifestations of CINCA syndrome are cutaneous signs, including maculopapular urticarial eruptions, commonly observed in the infantile period, joint involvement[]

  • Hyper IgD Syndrome

    […] periodic fever syndrome (HIDS) is an autosomal recessive auto-inflammatory disorder characterized by recurrent febrile attacks with lymphadenopathy, abdominal distress, skin eruptions[] In: Handbook of Systemic Autoimmune Disease. Vol. 6. Pediatrics in Systemic Autoimmune Disease. Cimas R, Lehman T, eds. Elsevier; 2008. P. 119-35. 4.[] A number of skin eruptions or rashes have been described in this syndrome, and these resolve slowly after the febrile episode settles.[]

  • Sweet Syndrome

    The eruption was brief and resolved spontaneously or following withdrawal of GCSF.[] French, Autoinflammation behind the curtain, British Journal of Dermatology, 178, 3, (581-582), (2018). Pedro Secchin, Maria K. Gomes, Danielle C.[] We report a 22-year-old woman with HSS, who, after minimal improvement with colchicine and dapsone, had significant improvement of her cutaneous eruption and systemic symptoms[]

  • Cherubism

    The disease also affects the normal eruption, occlusion and function of the dento-alveolar complex.[] systemic inflammation and bone destruction were rescued.[] Cherubism is an autosomal dominant disorder that may be related to tooth development and eruption.[]

  • Singleton Merten Syndrome

    Core manifestations are marked aortic calcification, dental anomalies (delayed eruption and immature root formation of primarily the anterior permanent teeth, and early loss[] Die Aktivierung der Interferon-induzierten Gene steht unter der Kontrolle des JAK/STAT-Systems.[] Dental concerns also emerged with delayed eruption and very malformed teeth with short roots.[]

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