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65 Possible Causes for Erythema Multiforme, Hyperglobulinemia, Lymphocytosis

  • Infectious Mononucleosis

    multiforme Erythema nodosum Urticaria including cold urticaria Urticarial vasculitis Acrocyanosis (bluish hands and feet) Annular erythema Pityriasis lichenoides Palmar dermatitis[dermnetnz.org] An atypical lymphocytosis of at least 20 percent or atypical lymphocytosis of at least 10 percent plus lymphocytosis of at least 50 percent strongly supports the diagnosis[ncbi.nlm.nih.gov] Lymph node biopsy was performed and he was diagnosed as atypical infectious mononucleosis (absence of fever, pharyngitis, lymphocytosis and negative atypical lymphocytosis[ncbi.nlm.nih.gov]

  • Non-Hodgkin Lymphoma

    It is characterized by hyperglobulinemia, excess bence-jones proteins (free monoclonal immunoglobulin light chains) in the urine, skeletal destruction, bone pain, and fractures[icd9data.com] Thrombocytosis and lymphocytosis may also occur. Renal function and electrolytes: obstructive nephropathy, hypercalcaemia. LFTs. Serology: HIV, HTLV-1, hepatitis C.[patient.info] […] lymphomatous meningitis GI obstruction, perforation, and bleeding in a patient with GI lymphoma (may also be caused by chemotherapy) Pain secondary to tumor invasion Leukocytosis (lymphocytosis[emedicine.medscape.com]

  • Viral Hepatitis

    Erythema multiforme – target-shaped lesions on hands and feet. Erythema nodosum – red lumps on shins.[dermnetnz.org] Path. 79:162- 70,1995).( lobular hepatitis). 2--more common lymphocytosis in sinusoids. 3--a strong lymphocytic infiltration of portal fields. 4--epithelial damage of portal[meddean.luc.edu] The most common hematological findings include leukocytosis in 70% of cases, with predominantly lymphocytosis and monocytosis, and mild thrombocytopenia in up to 50%.[doi.org]

  • Sarcoidosis

    […] nodosum : tender, 1-2cm bumps mostly on the shins; often accompanied by arthritis in the ankles, elbows, wrists and hands ( Löfgren syndrome ) nummular eczema erythema multiforme[dermnetnz.org] The cerebrospinal fluid analysis showed a moderately elevated protein content and a significant lymphocytosis 86.5%.[ncbi.nlm.nih.gov] Table 3 Investigation and treatment of Hypothalamo-pituitary sarcoid (HPS) Investigations that may help in the diagnosis of HPS Serum and CSF ACE CSF Increased protein Lymphocytosis[dx.doi.org]

  • Syphilis

    multiforme, pityriasis rubra pilaris, fungal infection, or, particularly, pityriasis rosea.[msdmanuals.com] The rash of secondary syphilis can mimic many dermatologic conditions, such as tinea versicolor, pityriasis rosea, scabies, fixed drug eruptions, and erythema multiforme;[hivinsite.ucsf.edu] […] soles Condyloma lata Risk factors (eg, HIV, multiple sex partners) Clinically, secondary syphilis may be mistaken for a drug eruption, rubella, infectious mononucleosis, erythema[msdmanuals.com]

  • Multiple Myeloma

    Thus, this study suggests that virtually all cases of CLL (both with mutated and unmutated IGHV genes) are preceded by monoclonal B-cell lymphocytosis.[doi.org] Schleinitz and Neil Caporaso , Diagnostic criteria for monoclonal B‐cell lymphocytosis , British Journal of Haematology , 130 , 3 , (325-332) , (2005) .[doi.org] Although recent data indicate that almost all CLL patients are preceded by a monoclonal B-cell lymphocytosis precursor state, patterns of immune defects preceding CLL diagnosis[doi.org]

  • Hodgkin Lymphoma

    Infection : Certain viral and bacterial infections that transform lymphocytes increase the risk, such as the Epstein-Barr virus (EBV), which causes glandular fever.[medicalnewstoday.com]

  • Malaria

    multiforme, Stevens-Johnson syndrome, toxic epidermal neurolysis, urticaria, exfoliative dermatitis, serum sickness, hepatitis, seizures, mental changes, gastrointestinal[msdmanuals.com] […] quinacrine or potentially hemolytic or bone marrow suppressing agents, G6PD deficiency, pregnancy (because G6PD status of the fetus is unknown) Pyrimethamine /sulfadoxine Erythema[msdmanuals.com]

  • Lymphogranuloma Venereum

    The skin may be affected by erythema multiforme, urticaria, erythema nodosum or scarlatiniform rash.[patient.info] Fever, lymphadenopathy, eosinophilia, lymphocytosis, hepatitis, and dermatitis: a severe adverse reaction to minocycline.[ncbi.nlm.nih.gov] However, it has also been associated with non-Hodgkin's lymphoma. [ 10 ] There is usually erythema and induration of skin overlying the enlarged nodes and there may be rupture[patient.info]

  • Histoplasmosis

    Erythema multiforme is a target or bull's eye type of skin reaction. This too is an immunologic reaction and organisms cannot be obtained from this site.[dermnetnz.org] Another 5% may develop rheumatologic problems like arthritis or skin disorders such as erythema nodosum or erythema multiforme .[emedicinehealth.com] […] nodosum and erythema multiforme CBC count: Thrombocytopenia in disseminated disease Serology: Useful in testing immunocompetent individuals with acute or subacute disease[emedicine.com]

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