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552 Possible Causes for Erythroblast

  • Chronic Alcoholism

    The concept of "structural plasticity" has emerged as a potential mechanism in neurodegenerative and psychiatric diseases such as drug abuse, depression, and dementia. Chronic alcoholism is a progressive neurodegenerative disease while the person continues to abuse alcohol, though clinical and imaging studies show[…][]

  • Thalassemia

    Markedly, however, no significant differences were observed between suppression of hepcidin as mediated by media from the culture of erythroblasts from normal controls and[] Conclusions: This is the first report on γ -globin induction by downregulation of SOX6 in human erythroblasts derived from β -thalassemia major.[] Myelogram performed in children, reveals dystrophic mature erythroblasts with hemoglobinization defect and basophil punctuations.[]

  • Primary Myelofibrosis

    Primary myelofibrosis is a chronic clonal myeloid disorder characterized by (1) anemia; (2) splenomegaly; (3) immature granulocytes, increased CD34 cells, erythroblasts, and[] The laboratory findings show a leuko-erythroblastic blood film, tear drop poikilocytosis, reticulin fibrosis in bone marrow and elevated levels of various inflammatory and[] The disease is a chronic clonal myeloid disorder characterized by (a) anemia, (b) splenomegaly, (c) immature granulocytes, erythroblasts, teardrop-shaped red cells and an[]

  • Congenital Dyserythropoietic Anemia

    […] of immature erythroblasts.[] However, immunofluorescence analysis of intermediate erythroblasts from patients with CDA-1 reveals abnormal accumulation of HP1α in the Golgi apparatus.[] Aberrations of erythroblast nuclear membrane which have not been hitherto noticed were as follows: The nuclear envelopes of erythroblasts frequently lacked heterochromatin[]

  • Fetal Erythroblastosis

    […] immature cells (erythroblasts) Preventing Erythroblastosis Fetalis RhoGram is admininstered to Rh- mothers at delivery.[] When the condition is moderate or severe, many erythroblasts are present in fetal blood , hence, the name, erythroblastosis fetalis .[] […] antibodies to an antigen in the blood of an Rh-positive fetus which cross the placenta and destroy fetal erythrocytes and that is characterized by an increase in circulating erythroblasts[]

  • Chronic Acquired Pure Red Cell Aplasia

    Development of two-stage erythroblast cytotoxicity method and role of complement. J Lab Clin Med 1973 ;82: 31 - 43 17.[] […] cytotoxicity against the erythroblasts [ 3, 5, 6 ].[] […] immunoglobulins Microscopic (histologic) description Bone marrow examination usually reveals complete loss of erythroid lineage Sometimes scattered, morphologically unremarkable erythroblasts[]

  • Pyruvate Kinase Deficiency

    In addition, bone marrow ultrastructural studies showed dyshemopoietic changes in all blood cell lines and especially in erythroblasts.[] Erythroid lineage analyses indicate that the number of total TER119 cells as well as the numbers of the different CD71 /CD44 erythroblast sub-populations were all found to[] Erythroblasts were elevated at 242/100 white blood cells.[]

  • Hereditary Sideroblastic Anemia

    Ring sideroblasts are erythroblasts characterized by iron accumulation in perinuclear mitochondria due to impaired iron utilization.[] The iron-loaded erythroblasts, which are present in bone marrow, are called ring sideroblasts.[] […] iron-binding capacity, increased (59)Fe clearance, low (59)Fe incorporation into erythrocytes, normal erythrocyte survival ((51)Cr), normal hemoglobin electrophoretic pattern, erythroblastic[]

  • Sideroblastic Anemia

    Erythroblasts express both IRP-repressible ALAS2 and non-IRP-repressible ferroportin 1b.[] About one fourth of normal immature red cells, mostly proerythroblasts and basophilic erythroblasts, showed diffuse cytoplasmic positivity for HF, but very few were positive[] The pathogenesis of mitochondrial iron loading in developing erythroblasts is diverse.[]

  • Acquired Sideroblastic Anemia

    CFU-E colonies consisted exclusively of normal-appearing erythroblasts, while ringed sideroblasts were observed only in scattered single erythroblasts or in small erythroblast[] In another case with no cytogenetic abnormality, repeated iron staining showed that 31% to 40% of CFU-E and 25% to 54% of BFU-E had erythroblasts with heavy iron deposits.[] Note several erythroblasts without apparent siderotic (blue-stained) granules.[]

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