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17 Possible Causes for Erythrocytes Decreased, Folic Acid Decreased, Polychromasia in Peripheral Blood Smear

  • Autoimmune Hemolytic Anemia

    Mechanisms of actions include suppression of autoantibody production, reduction in autoantibody affinity, and decreased destruction of erythrocytes by splenic macrophages,[doi.org] Peripheral blood smear showed polychromasia and spherocytosis. Haptoglobin level was 0.06 g/L ( N 0.16-2). Both hemoglobin electrophoresis and G6PD level were normal.[jahjournal.org] Some of these include: Vitamin B12 level —blood level may be low when deficient in B12 Folic acid level —blood level may be low if deficient in this B vitamin Methylmalonic[labtestsonline.org]

  • Sideroblastic Anemia

    […] protoporphyrin), decreased ferrochelatase activity, and deletion of portions of the long arms of chromosomes 18 and 20.[ncbi.nlm.nih.gov] Blood Smear Peripheral blood smear images .[imagebank.hematology.org] Folic acid can be given to compensate for increased erythropoiesis. Treatment of iron overload.[clinicaladvisor.com]

  • Congenital Hemolytic Anemia

    Phosphatidylserine internalization in erythrocytes with the mutant ATP11C was decreased 10-fold compared to that of the control, functionally establishing that ATP11C is a[ncbi.nlm.nih.gov] Laboratory The review of the peripheral blood smear revealed no evidence of the schistocytes or fragmented red cells.[medcraveonline.com] blood smear of Congenital Hemolytic Anemia Describe the extent of central pallor of a normal RBC T/F: There is increased reticulocytosis and polychromasia in Congenital Hemolytic[brainscape.com]

  • Anemia due to Glutathione Metabolism Disorder

    Addition of copper to normal erythrocytes led to increased autohemolysis, thermolability of hemoglobin, increased sensitivity to acetylphenylhydrazine, decreased erythrocyte[annals.org] The peripheral blood smear post-splenectomy often shows crenated or spiculated spherocytes and marked polychromasia.[clinicaladvisor.com] The mild form of glutathione synthetase deficiency (OMIM 231900) is associated with decreased erythrocyte glutathione levels and well-compensated hemolytic disease.[ommbid.mhmedical.com]

  • Sickle Cell Crisis

    A: Sickle-shaped erythrocytes cause cellular blockage in small vessels. B: Sickle-shaped erythrocytes cause decreased organ perfusion.[nurseslabs.com] Haematological indices revealed marked reticulocytosis (mean 14.39 (6.40)%) beyond the steady state levels (mean 6.41 (2.45)%), polychromasia on blood smears, and increased[adc.bmj.com] Prevention of Sickle Cell Crisis Take your daily dosage of minerals and vitamins regularly, as folic acid helps in preventing blood vessel problems associated with sickle[epainassist.com]

  • Acquired Sideroblastic Anemia

    […] than the decrease in number of erythrocytes. hypochromic microcytic anemia any anemia with microcytes that are hypochromic (reduced in size and in hemoglobin content); the[medical-dictionary.thefreedictionary.com] Blood Smear Peripheral blood smear images .[imagebank.hematology.org] Folic acid can be given to compensate for increased erythropoiesis. Treatment of iron overload.[clinicaladvisor.com]

  • Hereditary Sideroblastic Anemia

    Males affected with sideroblastic anemia had growth retardation, hypochromic microcytic anemia, elevated serum iron, decreased unsaturated iron-binding capacity, increased[ncbi.nlm.nih.gov] Blood Smear Peripheral blood smear images .[imagebank.hematology.org] Folic acid can be given to compensate for increased erythropoiesis. Treatment of iron overload.[clinicaladvisor.com]

  • Uremic Anemia

    […] in 38 hemodialysed patients was decreased and urea, creatinine and middle molecular substances had the effect on decreasing the osmotic resistance of erythrocyte in vitro[jstage.jst.go.jp] A peripheral blood smear showed red blood cell fragmentation with a few schistocytes (asterisk, 6/high power field) and polychromasia (arrow).[synapse.koreamed.org] However, the generation of anemia in CKD may be caused by more than one factor such as deficiency of iron, folic acid or vitamin B12, hemolysis, gastrointestinal losses and[revistanefrologia.com]

  • Pancytopenia

    One mechanism indicates direct effect of CMV on bone marrow cells leading to cellular injury and decrease of erythrocytes, lymphocytes, granulocytes, and platelets.[scielo.br] blood smear examination for which Leishman stain was used.[mjdrdypu.org] Folic acid and granulocyte colony-stimulating factor (G-CSF) were then prescribed.[archivesofrheumatology.org]

  • Normocytic Normochromic Anemia

    To start with a few definitions: Hemolysis: Any condition characterized by a significantly decreased erythrocyte life span.[web2.iadfw.net] Peripheral blood smear shows: Microcytosis and hypochromasia. There is anisocytosis, poikilocytosis. There are pencil cells (elliptical RBCs).[labpedia.net] The most common cause of this is folic acid or B12 deficiency Folic Acid Deficiency Causes Decreased intake likely secondary to alcohol abuse Decreased absorption – intake[physicianassistantexamreview.com]

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