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133 Possible Causes for Erythrocytes Decreased, Iron Increased, Reticulocyte Count Decreased

  • Iron Deficiency Anemia

    Normal 0.5-1.5% Hypoprolifearative: Decreased reticulocytes Bone marrow unable to produce requisite number of RBC's Lack of essential substance (iron, B12, folate) or invasion[meddean.luc.edu] Iron-deficient erythropoiesis: Iron stores in marrow are absent, iron and % saturation are beginning to decrease below reference intervals and iron-deficient erythrocytes[eclinpath.com] This is because your need for iron increases during these times of growth and development.[web.archive.org]

  • Pernicious Anemia

    Values obtained before treatment with cyanocobalamin were compared with those found during peak reticulocyte count.[ncbi.nlm.nih.gov] Individuals suffering iron deficiency might take oral iron supplements and increase their dietary iron intake, while individuals suffering from pernicious anemia might receive[livestrong.com] Response should be monitored by reticulocyte counts, lactic dehydrogenase (LDH), and an appropriate rise in hemoglobin levels.[emedicine.medscape.com]

  • Aplastic Anemia

    For example, for a person with anemia, an inappropriately low reticulocyte count often indicates decrease in red blood cell production in the bone marrow .[labtestsonline.org] We studied 4 adult AA patients who had transfusion-induced iron overload and showed hematological improvement after ICT with oral deferasirox.[ncbi.nlm.nih.gov] Stainable iron is usually increased; however, the presence of increased ringed sideroblasts suggests a diagnosis of MDS.[cancertherapyadvisor.com]

  • Folate-Deficiency Anemia

    Significant blood test findings include macrocytosis, decreased reticulocyte count, abnormal platelets, and a serum folate less than 4 mg/ml.[innvista.com] Serum folate reflects folate status unless intake has recently increased or decreased.[merckmanuals.com] Dangers of anaemia and iron deficiency less iron passing from mother to foetus so the newborn has low iron stores increased risk of blood loss during and after delivery, and[southsudanmedicaljournal.com]

  • Sideroblastic Anemia

    […] protoporphyrin), decreased ferrochelatase activity, and deletion of portions of the long arms of chromosomes 18 and 20.[ncbi.nlm.nih.gov] RBC indices reveal a decreased MCV, MCH, and a decreased reticulocyte count which correlates with Iron deficiency anemia.[usmleforum.com] Decreased ferritin increases synthesis of transferrin (increasing TIBC); such as seen in iron deficiency anemia.[forums.studentdoctor.net]

  • Acute Myelocytic Leukemia

    […] platelet count, and anemia due to decreased erythrocyte count.[medical-dictionary.thefreedictionary.com] An iron stain usually shows increased iron stores and may show ring sideroblasts (Figure 2, B [inset]).[archivesofpathology.org] The potential for neurotoxicity has aroused concern about the use of high-dose cytarabine in elderly patients who, ironically, have a higher likelihood of having drug-resistant[doi.org]

  • Leukemia

    Leukemia is a type of blood cancer that begins in the bone marrow. Bone marrow is the soft tissue in the center of the bones, where blood cells are produced. The term leukemia means white blood. White blood cells (leukocytes) are used by the body to fight infections and other foreign substances. Leukocytes are[…][medlineplus.gov]

  • Acute Myeloid Leukemia with Myelodysplasia-related Changes

    Mitochondrial pathology in MDS is suggested by abnormal mitochondrial iron accumulation, increased apoptosis, and a high frequency of acquired mitochondrial DNA mutations[ncbi.nlm.nih.gov]

  • Hereditary Spherocytosis

    At 1 year following partial splenectomy, mean hemoglobin significantly increased by 3.0 1.4 g/dL (n 52), reticulocyte count decreased by 6.6% 6.6% (n 41), and bilirubin level[ncbi.nlm.nih.gov] Defects in these proteins lead to a loss in RBC membrane cohesion and membrane surface area, resulting in erythrocyte sphering, decreased deformability and premature destruction[orpha.net] Indications for laparoscopic removal of the spleen included anemia unresponsive to iron supplementation in eight patients (66.6 %) with increase need for red cells transfusions[ncbi.nlm.nih.gov]

  • Chronic Kidney Insufficiency

    Because of increased iron utilization with stimulated erythropoiesis, iron stores must be replaced, often requiring parenteral iron.[merckmanuals.com] Iron therapy can help increase levels of iron in the body when EPO therapy alone is not effective. Vitamin D helps keep bones strong and healthy.[uwhealth.org] Contributing factors include anemia from reduced lifespan of the red blood cell, hemolysis and iron deficiency; falsely increased levels can occur from carbamylation of hemoglobin[clindiabetesendo.biomedcentral.com]

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