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19 Possible Causes for Erythrocytes Decreased, Mean Corpuscular Volume Decreased, Polychromasia in Peripheral Blood Smear

  • Sideroblastic Anemia

    Initial workup revealed hemoglobin 2.6 g/dL (10.2-12.7), hematocrit 7.7% (30.9-37.9), mean corpuscular volume 104 fL (71.3-82.6), white blood cell count 4200/μL (240 absolute[] […] protoporphyrin), decreased ferrochelatase activity, and deletion of portions of the long arms of chromosomes 18 and 20.[] Blood Smear Peripheral blood smear images .[]

  • Acquired Spherocytosis

    The RDW can be used, along with the mean corpuscular volume to identify the presence and cause of anemia.[] These patients also have a proportionate decrease in protein 4.2 content on the erythrocyte membrane.[] […] hemoglobin concentration (MCHC) and the mean corpuscular volume (MCV), and to examine the peripheral blood smear for the presence of spherocytes and polychromasia. 17 Typically[]

  • Acquired Sideroblastic Anemia

    Eleven weeks later, the patient's hemoglobin level and mean corpuscular volume had decreased to 9.8 g per deciliter (6.1 mmol per liter) and 59 micrometers 3 , respectively[] […] than the decrease in number of erythrocytes. hypochromic microcytic anemia any anemia with microcytes that are hypochromic (reduced in size and in hemoglobin content); the[] Blood Smear Peripheral blood smear images .[]

  • Hereditary Sideroblastic Anemia

    Eleven weeks later, the patient's hemoglobin level and mean corpuscular volume had decreased to 9.8 g per deciliter (6.1 mmol per liter) and 59 micrometers 3 , respectively[] […] and gama-interferon inhibit red cell production Shortened erythrocyte survival Autoimmune diseases may also cause antibody-mediated destruction CBC: Mild anemia (Hgb 9-11[] Blood Smear Peripheral blood smear images .[]

  • Autoimmune Hemolytic Anemia

    Average size of RBCs (mean corpuscular volume, MCV)—decreased Average amount of hemoglobin in RBCs (mean corpuscular hemoglobin, MCH)—decreased Hemoglobin concentration (mean[] Mechanisms of actions include suppression of autoantibody production, reduction in autoantibody affinity, and decreased destruction of erythrocytes by splenic macrophages,[] Peripheral blood smear showed polychromasia and spherocytosis. Haptoglobin level was 0.06 g/L ( N 0.16-2). Both hemoglobin electrophoresis and G6PD level were normal.[]

  • Nonimmune Hemolysis

    Keywords Haptoglobin; Inferior vena cava filter; Pulmonary embolism; Deep venous thrombosis Abbreviations DVT: Deep Venous Thrombosis; IVC: Inferior Vena Cava; MCV: Mean Corpuscular[] Premature destruction of erythrocytes occurs intravascularly or extravascularly. The etiologies of hemolysis often are categorized as acquired or hereditary.[] blood smear : spherocytes, polychromasia Coombs test : positive Cold agglutinins titer C3 and C4 ; (due to complement activation) Prognosis: spontaneous remission within[]

  • Congenital Hemolytic Anemia

    Mean corpuscular volume (MCV) is usually normal except in cases of severe HS when the MCV may be mildly decreased.[] Phosphatidylserine internalization in erythrocytes with the mutant ATP11C was decreased 10-fold compared to that of the control, functionally establishing that ATP11C is a[] Laboratory The review of the peripheral blood smear revealed no evidence of the schistocytes or fragmented red cells.[]

  • Uremic Anemia

    In normocytic anemias, the mean corpuscular volume (MCV) is within defined normal limits, but the hemoglobin and hematocrit are decreased.[] […] in 38 hemodialysed patients was decreased and urea, creatinine and middle molecular substances had the effect on decreasing the osmotic resistance of erythrocyte in vitro[] A peripheral blood smear showed red blood cell fragmentation with a few schistocytes (asterisk, 6/high power field) and polychromasia (arrow).[]

  • Pancytopenia

    In 42% of cases it was between 70,000 and 100,000/, and in 39% of cases it was The mean corpuscular volume (MCV) was increased in 49% of the total cases of pancytopenia[] One mechanism indicates direct effect of CMV on bone marrow cells leading to cellular injury and decrease of erythrocytes, lymphocytes, granulocytes, and platelets.[] blood smear examination for which Leishman stain was used.[]

  • Hemolytic Anemia

    Mean corpuscular volume and haptoglobin were significantly decreased, whereas RBC distribution width was increased.[] In general, any condition which shortens erythrocyte survival or decreases mean erythrocyte age, such as autoimmune hemolytic anemia, hereditary spherocytosis and elliptocytosis[] Mean corpuscular volume was 96 fl, and the reticulocyte count was 11%, with marked polychromasia on peripheral smear.[]

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