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42 Possible Causes for Erythrocytes Decreased, Polychromasia in Peripheral Blood Smear, Tachycardia

  • Autoimmune Hemolytic Anemia

    Physical findings are related to the degree of anemia and include pallor, resting tachycardia, mild jaundice and occasionally fever.[clinlabnavigator.com] Mechanisms of actions include suppression of autoantibody production, reduction in autoantibody affinity, and decreased destruction of erythrocytes by splenic macrophages,[doi.org] Peripheral blood smear showed polychromasia and spherocytosis. Haptoglobin level was 0.06 g/L ( N 0.16-2). Both hemoglobin electrophoresis and G6PD level were normal.[jahjournal.org]

  • Microangiopathic Hemolytic Anemia

    Severe anaemia, especially of sudden onset, may cause tachycardia, dyspnoea, angina and weakness. Gallstones may cause abdominal pain.[patient.info] […] than the decrease in number of erythrocytes. hypochromic microcytic anemia any anemia with microcytes that are hypochromic (reduced in size and in hemoglobin content); the[medical-dictionary.thefreedictionary.com] The peripheral blood smear revealed polychromasia, poikilocytosis, and many schistocytes. Bone marrow biopsy disclosed metastatic carcinoma.[ncbi.nlm.nih.gov]

  • Uremic Anemia

    His heart has a regular rhythm with tachycardia and a grade II/VI vibratory systolic ejection murmur at the left sternal border without radiation.[hawaii.edu] […] in 38 hemodialysed patients was decreased and urea, creatinine and middle molecular substances had the effect on decreasing the osmotic resistance of erythrocyte in vitro[jstage.jst.go.jp] A peripheral blood smear showed red blood cell fragmentation with a few schistocytes (asterisk, 6/high power field) and polychromasia (arrow).[synapse.koreamed.org]

  • Pyruvate Kinase Deficiency

    Among the symptoms of pyruvate kinase deficiency are: Mild to severe hemolytic Anemia Cholecystolithiasis Tachycardia Hemochromatosis Icteric sclera Splenomegaly Leg ulcers[en.wikipedia.org] decreased erythrocyte pyruvate kinase (PK) activity.[ncbi.nlm.nih.gov] Peripheral blood smear showed polychromasia, anisocytosis, tear drop cells, fragmented eyrtrocytes, and target cells.[ncbi.nlm.nih.gov]

  • Hemolytic Uremic Syndrome

    Patient 1 had rising fever, tachycardia, and severe abdominal pain 24 hours after admission.[ncbi.nlm.nih.gov] Anisocytosis, poikilocytosis, polychromasia, helmet cells, marked schistocytes, and rare platelets were observed in the peripheral blood smear, compatible with microangiopathic[ziaristionline.ro] At that time, she exhibited moderate dehydration, pallor, drowsiness, and a generalized seizure of 10 to 15 min duration, tachycardia, tender and tense abdominal wall, and[doi.org]

  • Atypical Hemolytic Uremic Syndrome

    Due to anemia, patients often appear pale or cyanotic, and tachycardia may be noted.[symptoma.com] Additionally the compound ACH-4471 significantly decreased C3 fragment deposition on paroxysmal nocturnal hemoglobinuria erythrocytes, indicating a reduced potential relative[ncbi.nlm.nih.gov] Anisocytosis, poikilocytosis, polychromasia, helmet cells, marked schistocytes, and rare platelets were observed in the peripheral blood smear, compatible with microangiopathic[ziaristionline.ro]

  • Anemia due to Glutathione Metabolism Disorder

    Addition of copper to normal erythrocytes led to increased autohemolysis, thermolability of hemoglobin, increased sensitivity to acetylphenylhydrazine, decreased erythrocyte[annals.org] The peripheral blood smear post-splenectomy often shows crenated or spiculated spherocytes and marked polychromasia.[clinicaladvisor.com] The mild form of glutathione synthetase deficiency (OMIM 231900) is associated with decreased erythrocyte glutathione levels and well-compensated hemolytic disease.[ommbid.mhmedical.com]

  • Congenital Dyserythropoietic Anemia

    Symptoms of anemia include fatigue, failure to thrive in infants, headache, dizziness, leg cramps, tachycardia and insomnia.[orpha.net] We also found that erythrocyte anion exchanger 1 protein is decreased in CDA-II homozygotes and obligate carriers alike.[ncbi.nlm.nih.gov] Anisopoikilocytosis with tear-drop forms, polychromasia, basophilic stippling in peripheral blood smear, erythroid hyperplasia with megaloblastoid changes, binucleated cells[ncbi.nlm.nih.gov]

  • Cold Agglutinin Disease

    These are common to any anemia and include, depending on the severity of anemia, pallor, fatigue, dyspnea, angina, tachycardia, tachypnea, and heart failure.[clinicaladvisor.com] The RBC count will be decreased due to doublet erythrocytes being counted as a single cell, thus resulting in a falsely high MCV. Hematocrit will also be lowered.[keralamedicaljournal.com] Reticulocytes and Spherocytes The results of the reticulocyte count are usually increased in patients with cold agglutinin disease, with polychromasia in the peripheral blood[web.archive.org]

  • Acquired Spherocytosis

    -Physical: Weakness, Pallor, Jaundice, Tachycardia -Labs: Down Hct, Up RC, Up Bilirubin -Diagnosis? Tests? Rx?[quizlet.com] These patients also have a proportionate decrease in protein 4.2 content on the erythrocyte membrane.[emedicine.medscape.com] […] hemoglobin concentration (MCHC) and the mean corpuscular volume (MCV), and to examine the peripheral blood smear for the presence of spherocytes and polychromasia. 17 Typically[pediatrics.aappublications.org]

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