Possible Causes for erythrocytosis Paraneoplastic Syndrome Paraneoplastic erythrocytosis was defined as a hemoglobin level greater than or equal to 16.7 g/dL in the absence of other causes of secondary erythrocytosis such as chronic [hindawi.com] Erythrocytosis is common in cancers of the liver, kidney, adrenal glands, lung, thymus, and CNS as well as in gynecologic tumors and myosarcomas. [emedicine.com] In contrast, survival of patients with paraneoplastic erythrocytosis was not significantly reduced. [hindawi.com] Myeloproliferative Disease These data suggest that erythrocytosis and granulocytosis in JAK2(V617F) mice are the net result of a complex interplay between cell intrinsic and extrinsic factors. [ncbi.nlm.nih.gov] Our data seem to indicate that both thrombocytosis and erythrocytosis resembled primary forms in these subjects; however, none of them suffered serious thrombotic and/or hemorrhagic [ncbi.nlm.nih.gov] Somatic Mutations of JAK2 Exon 12 in Patients with Polycythemia Vera or Idiopathic Erythrocytosis. [doi.org] Polycythemia Vera Unexpectedly, the symptom of erythrocytosis disappeared after the surgery. [ncbi.nlm.nih.gov] ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera? [mdedge.com] We report a case of erythrocytosis as the primary manifestation of a chronic myeloid leukemia, with the presence of the Philadelphia chromosome and the Breakpoint cluster [ncbi.nlm.nih.gov] Eisenmenger Syndrome When bunazosin was stopped, the erythrocytosis increased, but when it was resumed, the erythrocytosis and general fatigue diminished. [ncbi.nlm.nih.gov] Patients with either severe secondary erythrocytosis ( 220g/L) or anaemia ( CONCLUSIONS: Thrombocytopaenia significantly increased the risk of mortality in ES. [ncbi.nlm.nih.gov] […] pressures are 25 mmHg RVH develops in compensation shunting reverse in blood flow to become right-to-left cyanosis and respiratory distress clinically, this results in secondary erythrocytosis [step2.medbullets.com] Hypogonadism Erythrocytosis. Unstable severe congestive heart failure (class III or IV). [touchendocrinology.com] Erythrocytosis - avoid if pre-existing erythrocytosis is present (e.g., hematocrit 50%). [clinicaladvisor.com] Adverse effects of testosterone replacement include: Acne Prostate enlargement Stimulation of the growth of breast cancer or prostate cancer Sleep apnoea Heart failure Erythrocytosis [dermnetnz.org] Metastatic Renal Cell Carcinoma Tumor cells may produce erythropoietin and provoke erythrocytosis. [symptoma.com] […] abdominal mass;[9] malaise, which is a general feeling of unwellness;[9] weight loss and/or loss of appetite;[10] anaemia resulting from depression of erythropoietin;[8] erythrocytosis [en.wikipedia.org] Polycythemia ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera? [mdedge.com] Erythrocytosis and Polycythemia Overview of Erythrocytosis and Polycythemia [msdvetmanual.com] H&O How is erythrocytosis defined? JP Erythrocytosis is the presence of too many red blood cells. [hematologyandoncology.net] Polycythemia Neonatorum […] conjunctivitis Inclusion: Ophthalmia neonatorum due to gonococcus D45 Polycythemia vera excludes: familial polycythemia (D75.0) secondary polycythemia (D75.1) D75.0 Familial erythrocytosis [codelay.com] […] secondary) D75.1 ICD-10-CM Diagnosis Code D75.1 Secondary polycythemia 2016 2017 2018 2019 Billable/Specific Code Applicable To Acquired polycythemia Emotional polycythemia Erythrocytosis [icd10data.com] H Nagy K, Pomucz J, Varga R, Szabó E, Soltész G Erythrocytosis and severe asphyxia: two different causes of neonatal myocardial infarction. [medicbind.com] Secondary Polycythemia Out of these 53 patients, 28 (53%) patients had PV and 25 (47%) patients had secondary erythrocytosis. [bloodjournal.org] This is most likely due to the worse prognosis associated with the underlying disease causing erythrocytosis. [bloodjournal.org] At the same time, scientific literature is lacking in data about patients with secondary erythrocytosis and CVA. [bloodjournal.org] Erythrocytosis […] to an erythrocytosis. [ncbi.nlm.nih.gov] Patients with chronic interstitial lung disease and erythrocytosis could have normoxemia at rest and a normal or low serum erythropoietin level at the peak of erythrocytosis [ncbi.nlm.nih.gov] Uterine myomas are common but erythrocytosis caused by these is rarely seen. [ncbi.nlm.nih.gov] Gaisbock's Syndrome Erythrocytosis (disorder) Erythrocytosis NOS Erythrocytosis due to alveolar hypoventilation Erythrocytosis due to alveolar hypoventilation (disorder) Erythrocytosis due to [averbis.com] Primary and secondary erythrocytosis show true increase Relative erythrocytosis Hemoconcentration secondary to reduced plasma volume ETIOLOGY/PATHOGENESIS Multifactorial [basicmedicalkey.com] Synonym: spurious erythrocytosis; spurious polycythemia; stress erythrocytosis Gaisböck, (Gaisbock), Felix, German physician, 1868-1955. [medical-dictionary.thefreedictionary.com] Stress Polycythemia Called also benign or stress erythrocytosis, Gaisbцck disease, pseudopolycythemia, and benign, chronic relative, hypertonic, or spurious p. Medical dictionary. 2011. [medicine.academic.ru] Detection and accurate diagnosis of erythrocytosis is important regardless of its cause. [mhmedical.com] Synonym: erythrocytosis Chuvash polycythemia An autosomal recessive erythrocytosis in which patients respond to normal oxygen levels as if they were in an hypoxic environment [medical-dictionary.thefreedictionary.com] Cyanotic Congenital Heart Disease Secondary erythrocytosis of cyanotic congenital heart disease (CCHD) is pathologically different from primary erythrocytosis of polycythemia vera (PV). [ncbi.nlm.nih.gov] We describe the successful use of hydroxyurea (hydroxycarbamide) in four patients with uncorrected CCHD and symptomatic secondary erythrocytosis. [ncbi.nlm.nih.gov] Secondary erythrocytosis is an associated physiological response intended to increase circulating red blood cells and oxygen carrying capacity. [ncbi.nlm.nih.gov] Cerebellar Hemangioblastoma Cerebellar hemangioblastoma is a rare cause of secondary erythrocytosis. [ncbi.nlm.nih.gov] In a study of 26 cases of hemangioblastoma, we found extramedullary hematopoiesis in 4 tumors; one was associated with erythrocytosis. [ncbi.nlm.nih.gov] A patient with cerebellar hemangioblastoma and secondary erythrocytosis is presented. [ncbi.nlm.nih.gov] Post-Polycythemia Vera Myelofibrosis We describe how treatment with a JAK1/2 inhibitor, ruxolitinib, led to the rapid amelioration of marrow fibrosis, erythrocytosis and thrombocytopenia in a 77-year-old man [ncbi.nlm.nih.gov] […] see secondary erythrocytosis). [msdmanuals.com] Increased production confined to the RBC line is termed erythrocytosis; isolated erythrocytosis may occur with polycythemia vera but is more commonly due to other causes [msdmanuals.com] Red Blood Cell Disorder There are two types of erythrocytosis. [clearviewcancer.com] […] vera; Myeloproliferative disorder; Erythremia; Splenomegalic polycythemia; Vaquez's disease; Osler's disease; Polycythemia with chronic cyanosis - Myelopathic polycythemia; Erythrocytosis [sutterhealth.org] Hemosiderinuria Hereditary pyropoikilocytosis HFE hereditary haemochromatosis I Iron deficiency L Latent iron deficiency M McLeod syndrome Methemoglobinemia Microcytosis Myomatous erythrocytosis [en.wikipedia.org] Hemoglobinopathy The rare hemoglobinopathies with abnormal oxygen binding are usually characterized by erythropoietin-mediated erythrocytosis. [ncbi.nlm.nih.gov] Hemoglobin e trait Hemoglobin low Hemoglobin O-Arab trait Hemoglobin very high Hemoglobin Zurich disease Hemoglobinopathy Hemoglobinopathy with cyanosis Hemoglobinopathy with erythrocytosis [icd9data.com] Bare et al. first described a hemoglobinopathy with mild erythrocytosis in a 22-year-old Caucasian woman in 1976. These authors called the abnormal hemoglobin Hb York. [ncbi.nlm.nih.gov] Familial Polycythemia In some cases, the cause of erythrocytosis is unknown. Familial erythrocytosis can have different inheritance patterns depending on the gene involved. [ghr.nlm.nih.gov] Adamson JW et al. (1973) Recessive familial erythrocytosis: aspects of marrow regulation in two families. [ ] 18. Davey MG et al. (1968) Femilial erythrocytosis. [moldiag.com] erythrocytosis, androgen therapy, Cushing's disease, truncation of EPOR and hypertransfusion, in addition to the familial erythrocytosis and idiopathic erythrocytosis. [6 [sjmms.net] Hemoglobin Yakima In 1954 a then 31-yr-old male was found to have erythrocytosis. Over the ensuing decade he received 72 mCi32P. In 1964 his daughters were found to have erythrocytosis. [ncbi.nlm.nih.gov] Abstract In 1954 a then 31-yr-old male was found to have erythrocytosis. Over the ensuing decade he received 72 mCi32P. [bloodjournal.org] erythrocytosis, androgen therapy, Cushing's disease, truncation of EPOR and hypertransfusion, in addition to the familial erythrocytosis and idiopathic erythrocytosis. [6 [sjmms.net] Hereditary Neutrophilia Indexed on: 06 Sep '14 Published on: 06 Sep '14 Published in: Best Practice & Research: Clinical Haematology Abstract Hereditary erythrocytosis, thrombocytosis, and neutrophilia [sparrho.com] They include hereditary thrombocytosis ( THPO, MPL, JAK2 genes), hereditary erythrocytosis ( EPOR, VHL, EGLN1 and EPAS1 genes) and hereditary neutrophilia ( gene). [atlasgeneticsoncology.org] Some patients with primary hereditary erythrocytosis exhibit a mutation in the erythropoietin receptor (EPOR) which is associated with low serum erythropoietin (EPO) levels [sparrho.com] Iron Deficiency The patient presented for collection with a microcytic erythrocytosis. [ncbi.nlm.nih.gov] Peter Maxwell, Pathophysiology of anemia and erythrocytosis, Critical Reviews in Oncology/Hematology, 10.1016/j.critrevonc.2007.06.006, 64, 2, (139-158), (2007). MD. [doi.org] HPC-A collection from a patient with TEMPI syndrome was complicated by microcytic erythrocytosis, leading to RBC contamination and hemolysis in the product. [ncbi.nlm.nih.gov] Essential Thrombocythemia […] at diagnosis and for patients who subsequently develop thrombocytosis, leukocytosis, or erythrocytosis during follow-up, even for CML patients in complete cytogenetic response [ncbi.nlm.nih.gov] […] include essential thrombocythemia (ET), polycythemia vera (PV), chronic myeloid leukemia, and primary myelofibrosis (PMF), with the respective features of thrombocytosis, erythrocytosis [ncbi.nlm.nih.gov] Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms primarily characterized by erythrocytosis and thrombocytosis, respectively. [ncbi.nlm.nih.gov] Pickwickian Syndrome […] sounds Low voltage QRS complexes Diagnosis : Alveolar hypoventilation during wakefullness Chronic hypercapnic, hypoxic respiratory failure Respiratory acidosis Secondary erythrocytosis [medlibes.com] Complications of obesity hypoventilation syndrome include pulmonary hypertension ; right heart failure, also known as cor pulmonale; and secondary erythrocytosis. [nhlbi.nih.gov] Therapeutic Phlebotomy Polycythaemia Polycythaemia or erythrocytosis is a term used to describe an increase in the red blood cell mass. [ncbi.nlm.nih.gov] Therapeutic phlebotomy for polycythaemia patients Also called erythrocytosis, polycythaemia happens when there is an increase in the red blood cell mass. [ephlebotomytraining.com] The pathogenesis of post-transplant erythrocytosis is not fully understood but it appears to be multifactorial. [ncbi.nlm.nih.gov] Hemoglobin Chesapeake Erythrocytosis due to BPGM deficiency is very rare. [mdedge.com] […] vera or erythrocytosis of chronic lung disease. [hindawi.com] […] and alpha 1-globin gene variants in heterozygotes. [ PMID 17486491 ] Hb J-Cape Town [alpha92(FG4)Arg-- Gln (alpha1), CGG-- CAG] in Southern Italy found in a patient with erythrocytosis [snpedia.com] Hypoventilation Complications of obesity hypoventilation syndrome include pulmonary hypertension ; right heart failure, also known as cor pulmonale; and secondary erythrocytosis. [nhlbi.nih.gov] Treatment can prevent drops in the oxygen saturation of your blood, elevation in the red blood cell count called erythrocytosis, and heart failure (known as cor pulmonale [verywellhealth.com] Carboxyhemoglobinemia Abstract During a two-year period, we evaluated 14 patients with erythrocytosis. [ncbi.nlm.nih.gov] Classification of the Polycythemias Polycythemia, also called erythrocytosis, is an increase in the number of circulating red blood cells per volume of blood, as reflected [what-when-how.com] Other adults with cyanotic congenital heart disease have compensated erythrocytosis, in which a stable (though elevated) hemat-ocrit is maintained without overt symptoms of [what-when-how.com] Acute Cystitis […] pain, palpable abdominal mass) found only in 10% • Nonspecific symptoms common, often found accidentally (“internist’s tumor”) • Paraneoplastic syndromes: hypercalcemia, erythrocytosis [slideshare.net] Thrombocytopenia The CBC can tell us whether other blood disorders may be present, such as, anemia (low red cell count or hemoglobin), erythrocytosis (high red blood cell count or hemoglobin [medicinenet.com] Decreased Oxygen Carrying Capacity This study indicates that smoking causes mild erythrocytosis comparable to that seen in spurious or stress polycythemia. [bloodjournal.org] An erythrocytosis is the consequence of too many red cells; this results in hemoglobin levels above normal. [nurse-anesthesia.org] Dehydration ( heat exhaustion, no available source of fluids) Low availability of oxygen ( smoking, high altitude, pulmonary fibrosis) Genetic (congenital heart diseases) Erythrocytosis [emedicinehealth.com]
