Erythrocytosis: Causes & Reasons

Possible Causes for Erythrocytosis

These data suggest that erythrocytosis and granulocytosis in JAK2(V617F) mice are the net result of a complex interplay between cell intrinsic and extrinsic factors. [ncbi.nlm.nih.gov]

There have been no prospective national studies to estimate the incidence or outcomes of myeloproliferative disorders, persistent thrombocytosis or erythrocytosis in pregnancy [npeu.ox.ac.uk]

Our data seem to indicate that both thrombocytosis and erythrocytosis resembled primary forms in these subjects; however, none of them suffered serious thrombotic and/or hemorrhagic [ncbi.nlm.nih.gov]

Polycythemia Vera

ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera? [mdedge.com]

Unexpectedly, the symptom of erythrocytosis disappeared after the surgery. [ncbi.nlm.nih.gov]

We report a case of erythrocytosis as the primary manifestation of a chronic myeloid leukemia, with the presence of the Philadelphia chromosome and the Breakpoint cluster [ncbi.nlm.nih.gov]

Paraneoplastic Syndrome

Paraneoplastic erythrocytosis was defined as a hemoglobin level greater than or equal to 16.7 g/dL in the absence of other causes of secondary erythrocytosis such as chronic [hindawi.com]

Erythrocytosis is common in cancers of the liver, kidney, adrenal glands, lung, thymus, and CNS as well as in gynecologic tumors and myosarcomas. [emedicine.medscape.com]

In contrast, survival of patients with paraneoplastic erythrocytosis was not significantly reduced. [hindawi.com]

Metastatic Renal Cell Carcinoma

Tumor cells may produce erythropoietin and provoke erythrocytosis. [symptoma.com]

[…] abdominal mass;[9] malaise, which is a general feeling of unwellness;[9] weight loss and/or loss of appetite;[10] anaemia resulting from depression of erythropoietin;[8] erythrocytosis [en.wikipedia.org]

Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma is occasionally associated with erythrocytosis, hypothesized to result from tumoral production of erythropoietin. [ncbi.nlm.nih.gov]

[…] micro- or macroscopic hematuria occurs in 60% of patients Complete blood count (CBC) – patients may have anemia of chronic inflammation (normo- or microcytic), some have erythrocytosis [clinicaladvisor.com]

Eisenmenger Syndrome

When bunazosin was stopped, the erythrocytosis increased, but when it was resumed, the erythrocytosis and general fatigue diminished. [ncbi.nlm.nih.gov]

Because of the reversed flow, children with Eisenmenger syndrome have: Cyanosis: Pale blue or gray-looking skin due to low oxygen levels in the blood Erythrocytosis: An increase [nortonchildrens.com]

Patients with either severe secondary erythrocytosis (>220g/L) or anaemia ( CONCLUSIONS: Thrombocytopaenia significantly increased the risk of mortality in ES. [ncbi.nlm.nih.gov]

Polycythemia

ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera? [mdedge.com]

Erythrocytosis and Polycythemia Overview of Erythrocytosis and Polycythemia [msdvetmanual.com]

H&O How is erythrocytosis defined? JP Erythrocytosis is the presence of too many red blood cells. [hematologyandoncology.net]

Polycythemia Neonatorum

[…] the Bay of Naples.[15] Patients with Chuvash erythrocytosis experience a significantly elevated risk of events.[6] PHD2 erythrocytosis: Heterozygosity for loss-of-function [en.wikipedia.org]

CM Diagnosis Code D75.1 Secondary polycythemia 2016 2017 2018 2019 2020 2021 2022 2023 Billable/Specific Code Applicable To Acquired polycythemia Emotional polycythemia Erythrocytosis [icd10data.com]

[…] conjunctivitis Inclusion: Ophthalmia neonatorum due to gonococcus| D45 Polycythemia vera excludes: familial polycythemia (D75.0)| secondary polycythemia (D75.1)| D75.0 Familial erythrocytosis [codelay.com]

Gaisbock Syndrome

PRIMARY ERYTHROCYTOSIS The most commonly encountered form of primary erythrocytosis is an acquired myeloproliferative disorder called polycythemia vera. [basicmedicalkey.com]

TABLE 12-1Causes of Erythrocytosis View Table||Download (.pdf) TABLE 12-1 Causes of Erythrocytosis Primary (autonomous) erythrocytosis → Low plasma Epo Acquired: ... [accessmedicine.mhmedical.com]

Abstract Seven patients with unexplained erythrocytosis, moderate obesity, and mild hypertension without splenomegaly (Gaisböck's syndrome) were studied. [amjmed.com]

Secondary Polycythemia

Erythrocytosis What every physician needs to know: Erythrocytosis, also known as secondary polycythemia or secondary erythrocytosis to distinguish it from the chronic myeloproliferative [oncologynurseadvisor.com]

Out of these 53 patients, 28 (53%) patients had PV and 25 (47%) patients had secondary erythrocytosis. [bloodjournal.org]

erythrocytosis. [nature.com]

Stress Polycythemia

PRIMARY ERYTHROCYTOSIS The most commonly encountered form of primary erythrocytosis is an acquired myeloproliferative disorder called polycythemia vera. [basicmedicalkey.com]

Abstract Seven patients with unexplained erythrocytosis, moderate obesity, and mild hypertension without splenomegaly (Gaisböck's syndrome) were studied. [amjmed.com]

Erythrocytosis

In addition, EPO levels are a very useful tool in recognizing the nature of erythrocytosis. [symptoma.com]

[…] to an erythrocytosis. [ncbi.nlm.nih.gov]

Patients with chronic interstitial lung disease and erythrocytosis could have normoxemia at rest and a normal or low serum erythropoietin level at the peak of erythrocytosis [ncbi.nlm.nih.gov]

Cyanotic Congenital Heart Disease

Secondary erythrocytosis of cyanotic congenital heart disease (CCHD) is pathologically different from primary erythrocytosis of polycythemia vera (PV). [ncbi.nlm.nih.gov]

We describe the successful use of hydroxyurea (hydroxycarbamide) in four patients with uncorrected CCHD and symptomatic secondary erythrocytosis. [ncbi.nlm.nih.gov]

Secondary erythrocytosis is an associated physiological response intended to increase circulating red blood cells and oxygen carrying capacity. [ncbi.nlm.nih.gov]

Post-Polycythemia Vera Myelofibrosis

We describe how treatment with a JAK1/2 inhibitor, ruxolitinib, led to the rapid amelioration of marrow fibrosis, erythrocytosis and thrombocytopenia in a 77-year-old man [ncbi.nlm.nih.gov]

[…] see secondary erythrocytosis). [msdmanuals.com]

Increased production confined to the RBC line is termed erythrocytosis; isolated erythrocytosis may occur with polycythemia vera but is more commonly due to other causes [msdmanuals.com]

Hemoglobin Yakima

Abstract Erythrocytosis without clinical illness was noted in a man and his two daughters. [ncbi.nlm.nih.gov]

erythrocytosis, androgen therapy, Cushing's disease, truncation of EPOR and hypertransfusion, in addition to the familial erythrocytosis and idiopathic erythrocytosis. [6 [sjmms.net]

Regulation of erythropoiesis was studied in affected members of families having either hemoglobin Rainier or Yakima, abnormal hemoglobins associated with erythrocytosis. [pubfacts.com]

Red Blood Cell Disorder

There are two types of erythrocytosis. [clearviewcancer.com]

[…] vera; Myeloproliferative disorder; Erythremia; Splenomegalic polycythemia; Vaquez's disease; Osler's disease; Polycythemia with chronic cyanosis - Myelopathic polycythemia; Erythrocytosis [sutterhealth.org]

Hemosiderinuria Hereditary pyropoikilocytosis HFE hereditary haemochromatosis I Iron deficiency L Latent iron deficiency M McLeod syndrome Methemoglobinemia Microcytosis Myomatous erythrocytosis [en.wikipedia.org]

Familial Polycythemia

Familial erythrocytosis-2 has characteristics of both primary and secondary erythrocytosis (Prchal, 2005). [bloodgenetics.com]

In some cases, the cause of erythrocytosis is unknown. Familial erythrocytosis can have different inheritance patterns depending on the gene involved. [ghr.nlm.nih.gov]

Adamson JW et al. (1973) Recessive familial erythrocytosis: aspects of marrow regulation in two families. [^] 18. Davey MG et al. (1968) Femilial erythrocytosis. [moldiag.com]

Hemoglobin Chesapeake

Erythrocytosis due to BPGM deficiency is very rare. [mdedge.com]

[…] vera or erythrocytosis of chronic lung disease. [hindawi.com]

[…] and alpha 1-globin gene variants in heterozygotes. [ PMID 17486491 ] Hb J-Cape Town [alpha92(FG4)Arg-->Gln (alpha1), CGG-->CAG] in Southern Italy found in a patient with erythrocytosis [snpedia.com]

Primary Male Hypogonadism

Erythrocytosis (increase in proportion of red blood cells) is an adverse effect of testosterone-replacement therapy. [medivizor.com]

Erythrocytosis. Unstable severe congestive heart failure (class III or IV). [touchendocrinology.com]

Erythrocytosis – avoid if pre-existing erythrocytosis is present (e.g., hematocrit >50%). [clinicaladvisor.com]

Hemoglobin E Disease

Hematological investigations of these individuals reveal a mild microcytosis, hypochromia and erythrocytosis as seen with the β-thalassemia trait. [jdrntruhs.org]

Hematological investigations of these individuals reveal mild microcytosis, hypochromia and erythrocytosis as seen with the β-thalassemia trait. [ijpmonline.org]

HbE disease causes only a mild, usually asymptomatic anemia with microcytosis and erythrocytosis. [jlponline.org]

Cerebellar Hemangioblastoma

Cerebellar hemangioblastoma is a rare cause of secondary erythrocytosis. [ncbi.nlm.nih.gov]

A patient with cerebellar hemangioblastoma and secondary erythrocytosis is presented. [ncbi.nlm.nih.gov]

There is erythrocytosis with no associated splenomegaly or increase in the white cell or platelet count. [neurosurgery.me]

Decreased Oxygen Carrying Capacity

This study indicates that smoking causes mild erythrocytosis comparable to that seen in spurious or stress polycythemia. [bloodjournal.org]

An erythrocytosis is the consequence of too many red cells; this results in hemoglobin levels above normal. [nurse-anesthesia.org]

Dehydration ( heat exhaustion, no available source of fluids) Low availability of oxygen ( smoking, high altitude, pulmonary fibrosis) Genetic (congenital heart diseases) Erythrocytosis [emedicinehealth.com]

Congenital Heinz Body Hemolytic Anemia

Finazzi et al., Idiopathic erythrocytosis and other non-clonal polycythemias. Best Pract Res Clin Haematol. 19, 471 (2006) G. Weiss et al.,) Anemia of Chronic Disease. [charite.de]

Hemoglobin e trait Hemoglobin low Hemoglobin O-Arab trait Hemoglobin very high Hemoglobin Zurich disease Hemoglobinopathy Hemoglobinopathy with cyanosis Hemoglobinopathy with erythrocytosis [icd9data.com]

[…] conditions cannot occur together, such as a congenital form versus an acquired form of the same condition. familial polycythemia ( ICD-10-CM Diagnosis Code D75.0 Familial erythrocytosis [icd10data.com]

Hemoglobinopathy

The rare hemoglobinopathies with abnormal oxygen binding are usually characterized by erythropoietin-mediated erythrocytosis. [ncbi.nlm.nih.gov]

Certain forms may even be accompanied by erythrocytosis, hemoglobinemia and increased hematokrit (please also refer to pathophysiology). [symptoma.com]

Hereditary Neutrophilia

Indexed on: 06 Sep '14 Published on: 06 Sep '14 Published in: Best Practice & Research: Clinical Haematology Abstract Hereditary erythrocytosis, thrombocytosis, and neutrophilia [sparrho.com]

They include hereditary thrombocytosis ( THPO, MPL, JAK2 genes), hereditary erythrocytosis ( EPOR, VHL, EGLN1 and EPAS1 genes) and hereditary neutrophilia ( gene). [atlasgeneticsoncology.org]

Some patients with primary hereditary erythrocytosis exhibit a mutation in the erythropoietin receptor (EPOR) which is associated with low serum erythropoietin (EPO) levels [sparrho.com]

Male Hypogonadism

Contraindications to testosterone-replacement therapy include prostate and breast cancers, uncontrolled congestive heart failure, severe lower-urinary-tract symptoms, and erythrocytosis [ncbi.nlm.nih.gov]

Erythrocytosis. Unstable severe congestive heart failure (class III or IV). [touchendocrinology.com]

Adverse effects of testosterone replacement include: Acne Prostate enlargement Stimulation of the growth of breast cancer or prostate cancer Sleep apnoea Heart failure Erythrocytosis [dermnetnz.org]

Hypogonadism

Erythrocytosis. Unstable severe congestive heart failure (class III or IV). [touchendocrinology.com]

Erythrocytosis - avoid if pre-existing erythrocytosis is present (e.g., hematocrit >50%). [clinicaladvisor.com]

Hemolytic Anemia due to Glycolytic Enzyme Deficiency

Journal Ann Pharmacother 44:1327-9 (2010) DOI: 10.1345/aph.1P030 Reference PMID: 15054810 Authors Hoyer JD, Allen SL, Beutler E, Kubik K, West C, Fairbanks VF Title Erythrocytosis [genome.jp]

Deficiencies of BPGM and bisphosphoglycerate phosphatase are associated with mild erythrocytosis secondary to virtual absence of 2,3-DPG. [ommbid.mhmedical.com]

D7389Other diseases of spleen D739Disease of spleen, unspecified D740Congenital methemoglobinemia D748Other methemoglobinemias D749Methemoglobinemia, unspecified D750Familial erythrocytosis [cms.gov]

Thrombocytosis

Primary causes may be suspected if there is an associated erythrocytosis or leucocytosis. Complications of primary MPNs include arterial or venous occlusive events. [apps.nhslothian.scot]

[…] is found in the vast majority of patients with polycythemia vera (PV) and this change is proposed to be one of diagnostic tools for PV, 1 while the presence of idiopathic erythrocytosis [nature.com]

Control subjects include healthy individuals and patients with secondary erythrocytosis who did not carry the JAK2 (V617F) mutation. [dx.doi.org]

Pickwickian Syndrome

[…] sounds Low voltage QRS complexes Diagnosis : Alveolar hypoventilation during wakefullness Chronic hypercapnic, hypoxic respiratory failure Respiratory acidosis Secondary erythrocytosis [medlibes.com]

It is named after the fat boy Joe in The Pickwick Papers of Charles Dickens. pickwickian syndrome alveolar hypoventilation, somnolence and erythrocytosis associated with extreme [medical-dictionary.thefreedictionary.com]

Complications of obesity hypoventilation syndrome include pulmonary hypertension ; right heart failure, also known as cor pulmonale; and secondary erythrocytosis. [nhlbi.nih.gov]