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198 Possible Causes for Erythrocytosis, Iron Decreased, Splenomegaly

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[] […] numbers of cells. lack of iron making RBC formation difficult spread of other diseases to the bone marrow Diseases of the different cell types Cell types and functions: White[] These data suggest that erythrocytosis and granulocytosis in JAK2(V617F) mice are the net result of a complex interplay between cell intrinsic and extrinsic factors.[]

  • Polycythemia Vera

    […] symptoms in the phase 3 RESPONSE study of patients with polycythemia vera with splenomegaly who experienced an inadequate response to or adverse effects from hydroxyurea.[] Polycythemia Vera Laboratory findings Elevated Hct – often 60% Increased WBCs and platelets Serum EPO levels are low Decreased iron stores (Ferritin) Increased Vitamin B12[] ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera?[]

  • Erythropoietic Protoporphyria

    As hepatic complications worsen the patient will develop splenomegaly, leading to entrapment and hemolysis of erythrocytes.[] Iron stores, assessed by serum ferritin (sFn), were decreased by two-thirds, but normal serum soluble transferrin receptor-1 and iron concentrations suggested that erythropoiesis[] […] erythroblastosis 胎児赤芽球症 erythrocyte cast/red blood cell cast 赤血球円柱 erythrocyte deformability 赤血球変形能 erythrocyte inclusion 赤血球封入体 erythrocyte osmotic fragility 赤血球浸透圧脆弱性 erythrocytosis[]

  • Polycythemia

    Patient demographics, laboratory data, and the presence of splenomegaly by disease feature including known HU use, known phlebotomy requirements, and the presence of splenomegaly[] In addition, inducing a chronic state of iron-deficiency can help people with polycythemia by decreasing blood production.[] ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera?[]

  • Familial Polycythemia

    289.52 Splenic sequestration 289.53 Neutropenic splenomegaly 289.59 Other diseases of spleen 289.7 Methemoglobinemia 289.81 Primary hypercoagulable state 289.82 Secondary[] However, the major influence is hypoxia, including factors of decreased oxygen tension, RBC loss, and increased oxygen affinity of hemoglobin.[] In some cases, the cause of erythrocytosis is unknown. Familial erythrocytosis can have different inheritance patterns depending on the gene involved.[]

  • Post-Polycythemia Vera Myelofibrosis

    Our present case suggests the potential risk of TLS development after ruxolitinib treatment, particularly in patients with massive splenomegaly.[] The removal of blood from the body induces iron deficiency, thereby decreasing the haemoglobin / hematocrit level, and reducing the risk of blood clots.[] We describe how treatment with a JAK1/2 inhibitor, ruxolitinib, led to the rapid amelioration of marrow fibrosis, erythrocytosis and thrombocytopenia in a 77-year-old man[]

  • Essential Thrombocythemia

    […] essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly[] Prussian blue iron stain shows decreased storage iron and no significant increase in ring sideroblasts.[] […] at diagnosis and for patients who subsequently develop thrombocytosis, leukocytosis, or erythrocytosis during follow-up, even for CML patients in complete cytogenetic response[]

  • Gaisbock's Syndrome

    Gaisböck disease - polycythemia associated with hypertension but without splenomegaly. Synonym(s): Gaisböck syndrome ; polycythemia hypertonica[] Decreased stainable iron. Spent phase - tear drops, reticulin fibrosis and extramed hematopoesis. MOST COMMON CAUSE OF DEATH thrombosis and acute leukemia. MPD ESP.[] Primary and secondary erythrocytosis show true increase Relative erythrocytosis Hemoconcentration secondary to reduced plasma volume ETIOLOGY/PATHOGENESIS Multifactorial[]

  • Stress Polycythemia

    ., without leukocytosis, splenomegaly, or thrombocytosis.[] The plasma iron in such patients is decreased, the iron binding capacity increased, and plasma ferritin levels are low.[] 447 Splenomegaly and Hepatomegaly 448 Spontaneous Miscarriage 450 Squamous Cell Carcinoma 451 Status Epilepticus 452 Stomatitis Bullous 453 Stomatitis Red Lesions 454 Strabismus[]

  • Hemolytic Anemia

    It results in hemolytic anemia and splenomegaly.[] These may include: Serum iron —the level of iron in someone's blood, which is usually decreased Ferritin —a protein used to store iron; the small quantity of ferritin that[] Intrinsic hemolytic anemias are often inherited, such as sickle cell anemia, thalassemia, or erythrocytosis.[]

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