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421 Possible Causes for Erythrocytosis, Polycythemia, Splenomegaly

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[] Bone marrow fibrosis is also detected in the spent phase of chronic myelogenous leukemia and polycythemia vera. See Workup for more detail.[] These data suggest that erythrocytosis and granulocytosis in JAK2(V617F) mice are the net result of a complex interplay between cell intrinsic and extrinsic factors.[]

  • Polycythemia Vera

    […] symptoms in the phase 3 RESPONSE study of patients with polycythemia vera with splenomegaly who experienced an inadequate response to or adverse effects from hydroxyurea.[] […] as a primary polycythemia.[] ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera?[]

  • Familial Polycythemia

    289.52 Splenic sequestration 289.53 Neutropenic splenomegaly 289.59 Other diseases of spleen 289.7 Methemoglobinemia 289.81 Primary hypercoagulable state 289.82 Secondary[] Their differentiation from polycythemia vera (PV) is crucial to avoid therapy which is otherwise reserved for PV patients.[] In some cases, the cause of erythrocytosis is unknown. Familial erythrocytosis can have different inheritance patterns depending on the gene involved.[]

  • Polycythemia

    Patient demographics, laboratory data, and the presence of splenomegaly by disease feature including known HU use, known phlebotomy requirements, and the presence of splenomegaly[] Secondary polycythemia in which the production of erythropoietin increases appropriately is called physiologic polycythemia.[] ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera?[]

  • Stress Polycythemia

    ., without leukocytosis, splenomegaly, or thrombocytosis.[] Polycythemia polycythemia Any RBC mass. See Relative polycythemia, Secondary polycythemia.[] 447 Splenomegaly and Hepatomegaly 448 Spontaneous Miscarriage 450 Squamous Cell Carcinoma 451 Status Epilepticus 452 Stomatitis Bullous 453 Stomatitis Red Lesions 454 Strabismus[]

  • Post-Polycythemia Vera Myelofibrosis

    Our present case suggests the potential risk of TLS development after ruxolitinib treatment, particularly in patients with massive splenomegaly.[] Post-polycythemia vera myelofibrosis is a condition in which polycythemia vera, a disorder of excessive red cell production, triggers malignant transformation of hematopoietic[] We describe how treatment with a JAK1/2 inhibitor, ruxolitinib, led to the rapid amelioration of marrow fibrosis, erythrocytosis and thrombocytopenia in a 77-year-old man[]

  • Essential Thrombocythemia

    […] essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly[] IM - Review First Online: 30 September 2009 Abstract The classic myeloproliferative neoplasms (MPNs) include polycythemia vera and essential thrombocythemia; their molecular[] […] at diagnosis and for patients who subsequently develop thrombocytosis, leukocytosis, or erythrocytosis during follow-up, even for CML patients in complete cytogenetic response[]

  • Gaisbock's Syndrome

    Gaisböck disease - polycythemia associated with hypertension but without splenomegaly. Synonym(s): Gaisböck syndrome ; polycythemia hypertonica[] Stress Polycythemia.[] Primary and secondary erythrocytosis show true increase Relative erythrocytosis Hemoconcentration secondary to reduced plasma volume ETIOLOGY/PATHOGENESIS Multifactorial[]

  • Secondary Polycythemia

    There is splenomegaly. The JAK2 mutation is seen in granulocytes in almost 100% of the cases. There is increased serum vitamin B 12 and B 12 - binding capacity.[] polycythemia (SP).[] Out of these 53 patients, 28 (53%) patients had PV and 25 (47%) patients had secondary erythrocytosis.[]

  • Primary Myelofibrosis

    Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[] Megakaryocytes are the "hallmark" of Philadelphia chromosome-negative myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera, and primary myelofibrosis[] The laboratory findings showed leuko-and erythrocytosis, increased levels of urea-BUN (32 mmol/l) and creatinine (766 mmol/l) as well as uric acid (920 mmol/l).[]

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