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421 Possible Causes for Erythrocytosis, Polycythemia, Splenomegaly

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] Bone marrow fibrosis is also detected in the spent phase of chronic myelogenous leukemia and polycythemia vera. See Workup for more detail.[emedicine.com] These data suggest that erythrocytosis and granulocytosis in JAK2(V617F) mice are the net result of a complex interplay between cell intrinsic and extrinsic factors.[ncbi.nlm.nih.gov]

  • Polycythemia Vera

    […] symptoms in the phase 3 RESPONSE study of patients with polycythemia vera with splenomegaly who experienced an inadequate response to or adverse effects from hydroxyurea.[ncbi.nlm.nih.gov] […] as a primary polycythemia.[symptoma.com] ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera?[mdedge.com]

  • Familial Polycythemia

    289.52 Splenic sequestration 289.53 Neutropenic splenomegaly 289.59 Other diseases of spleen 289.7 Methemoglobinemia 289.81 Primary hypercoagulable state 289.82 Secondary[healthprovidersdata.com] Their differentiation from polycythemia vera (PV) is crucial to avoid therapy which is otherwise reserved for PV patients.[ncbi.nlm.nih.gov] In some cases, the cause of erythrocytosis is unknown. Familial erythrocytosis can have different inheritance patterns depending on the gene involved.[ghr.nlm.nih.gov]

  • Polycythemia

    Patient demographics, laboratory data, and the presence of splenomegaly by disease feature including known HU use, known phlebotomy requirements, and the presence of splenomegaly[medpagetoday.com] Secondary polycythemia in which the production of erythropoietin increases appropriately is called physiologic polycythemia.[en.wikipedia.org] ERYTHROCYTOSIS AND POLYCYTHEMIA VERA 1. In patients with erythrocytosis, which of the following is not characteristic of polycythemia vera?[mdedge.com]

  • Stress Polycythemia

    ., without leukocytosis, splenomegaly, or thrombocytosis.[medicine.academic.ru] Polycythemia polycythemia Any RBC mass. See Relative polycythemia, Secondary polycythemia.[medical-dictionary.thefreedictionary.com] 447 Splenomegaly and Hepatomegaly 448 Spontaneous Miscarriage 450 Squamous Cell Carcinoma 451 Status Epilepticus 452 Stomatitis Bullous 453 Stomatitis Red Lesions 454 Strabismus[books.google.de]

  • Post-Polycythemia Vera Myelofibrosis

    Our present case suggests the potential risk of TLS development after ruxolitinib treatment, particularly in patients with massive splenomegaly.[ncbi.nlm.nih.gov] Post-polycythemia vera myelofibrosis is a condition in which polycythemia vera, a disorder of excessive red cell production, triggers malignant transformation of hematopoietic[symptoma.com] We describe how treatment with a JAK1/2 inhibitor, ruxolitinib, led to the rapid amelioration of marrow fibrosis, erythrocytosis and thrombocytopenia in a 77-year-old man[ncbi.nlm.nih.gov]

  • Essential Thrombocythemia

    […] essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly[ncbi.nlm.nih.gov] IM - Review First Online: 30 September 2009 Abstract The classic myeloproliferative neoplasms (MPNs) include polycythemia vera and essential thrombocythemia; their molecular[doi.org] […] at diagnosis and for patients who subsequently develop thrombocytosis, leukocytosis, or erythrocytosis during follow-up, even for CML patients in complete cytogenetic response[ncbi.nlm.nih.gov]

  • Gaisbock's Syndrome

    Gaisböck disease - polycythemia associated with hypertension but without splenomegaly. Synonym(s): Gaisböck syndrome ; polycythemia hypertonica[medical-dictionary.thefreedictionary.com] Stress Polycythemia.[malacards.org] Primary and secondary erythrocytosis show true increase Relative erythrocytosis Hemoconcentration secondary to reduced plasma volume ETIOLOGY/PATHOGENESIS Multifactorial[basicmedicalkey.com]

  • Secondary Polycythemia

    There is splenomegaly. The JAK2 mutation is seen in granulocytes in almost 100% of the cases. There is increased serum vitamin B 12 and B 12 - binding capacity.[labpedia.net] polycythemia (SP).[symptoma.com] Out of these 53 patients, 28 (53%) patients had PV and 25 (47%) patients had secondary erythrocytosis.[bloodjournal.org]

  • Primary Myelofibrosis

    Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[ncbi.nlm.nih.gov] Megakaryocytes are the "hallmark" of Philadelphia chromosome-negative myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera, and primary myelofibrosis[ncbi.nlm.nih.gov] The laboratory findings showed leuko-and erythrocytosis, increased levels of urea-BUN (32 mmol/l) and creatinine (766 mmol/l) as well as uric acid (920 mmol/l).[ncbi.nlm.nih.gov]

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