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12 Possible Causes for Eschar Formation, Pruritic Rash, Severe Abdominal Pain

  • Calciphylaxis

    This is followed by necrosis, ulcers, eschar formation, and possibly gangrene.[visualdx.com] Two weeks following surgery, the patient developed severe respiratory distress, abdominal pain, and subsequently required transfer to the ICU.[o-wm.com] This may progress to violaceous indurated plaques and nodules or frank necrosis with eschar formation and subsequent gangrenous infection and sepsis.[woundsresearch.com]

  • Drug Eruptions

    rash.[consultant360.com] formation Warfarin, heparin, barbiturates, epinephrine, norepinephrine, vasopressin, levamisole (contaminant in street preparations of cocaine) Drug-induced lupus Appears[merckmanuals.com] pain with diarrhoea.[eurekaselect.com]

  • Chemical Burn of the Esophagus

    Acids cause coagulation necrosis, which is characterized by the formation of eschar.[mhmedical.com] Peritonitis results in severe abdominal pain when the stomach perforates.[msdmanuals.com] Because of the eschar formation, there is often limited substance penetration and decreased depth of injury.[clinicaladvisor.com]

  • Typhus

    Two weeks earlier, she had noticed a transient pruritic rash on her abdomen, which had appeared after she had been collecting firewood in a local forest clearing.[nejm.org] formation, since scrub typhus may present with acute cholecystitis.[ncbi.nlm.nih.gov] Murine typhus in children exhibits several different characteristics, with abdominal pain, diarrhea, and sore throat reported more commonly, higher frequency of anemia, lower[ncbi.nlm.nih.gov]

  • Tsutsugamushi Disease

    Two weeks earlier, she had noticed a transient pruritic rash on her abdomen, which had appeared after she had been collecting firewood in a local forest clearing.[dx.doi.org] Only one patient was serology and PCR positive and showed eschar formation.[ijpmonline.org] Gastrointestinal signs included hepatomegaly, jaundice and abdominal pain.[histopathology-india.net]

  • Brown Recluse Spider Bite

    “Localized Pruritic Rash Due to Recurrent Spider Bites.” J. Geriatr. Dermatol. 3(6): 186–190. McKeown, N., R. S. Vetter, and R. G. Hendrickson. 2014.[ento.psu.edu] The bleb ruptures, causing necrosis in the next 3 to 4 days, followed by eschar formation between 5 and 7 days. 4 Between 7 and 14 days, the eschar falls off and leaves an[o-wm.com] Symptoms include severe muscle cramps, abdominal pain , weakness, and tremor.[onhealth.com]

  • Pityriasis Lichenoides et Varioliformis

    As expected, a range of clinical presentations was reported, including single nodules, plaques, multiple pruritic papules, or a rash-like presentation.[academic.oup.com] formation.[pedsinreview.aappublications.org] (40 to 41 C), neurological signs, asthenia and impaired general state, abdominal pain, interstitial lung disease, lymphocytic myocarditis, rheumatologic manifestations and[therapeutique-dermatologique.org]

  • Spotted Fever Rickettsiosis

    On Day 5, a non-pruritic rash appeared on the trunk and subsequently spread to the extremities, including the palms and soles.[mja.com.au] This usually becomes necrotic and forms a typical black eschar (scab).[www2.health.vic.gov.au] Eyes can become red, muscles may feel tender, and there may be abdominal pain, nausea, vomiting, poor appetite, and fatigue.[kidshealth.org]

  • Epidemic Typhus

    Duration of untreated illness 12 days Symptoms: Headache-myalgia-nausea-malaise-chills – fever-macular rash – Pulmonary: cough- pneumonia- Complication: bleeding disorder-[the-travel-doctor.com] Non-specific symptoms sometimes include a cough, abdominal pain, nausea and diarrhoea.[microbiologysociety.org] pain diarrhea backache headache extremely high fever (105-106 F) may last for up to two weeks dull, red rash begins on the trunk and spreads peripherally hacking, dry cough[medbullets.com]

  • Syndromic Multisystem Autoimmune Disease due to ITCH Deficiency

    When the rash first develops, it usually is not itchy (not pruritic). However, in approximately 45 percent of cases, the rash will become itchy within a few years.[rarediseases.org] The eschar may eventually slough or require extensive surgical debridement.[emedicine.medscape.com] Occasionally, severe hypokalemia due to the loss of potassium in the stool can cause muscle weakness.  Severe abdominal pain (prevalence 34-64%) is unusual in patients with[slideshare.net]