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16 Possible Causes for Eschar Formation, Pyoderma Gangrenosum, Severe Abdominal Pain

  • Ischemic Ulcer

    Three patients (9%) died of sepsis, 2 of whom were undergoing immunosuppressive treatment for wrongly diagnosed pyoderma gangrenosum.[] Eutrophication 12 represents the proximal pattern of nonuremic calciphylaxis. 13, 14 Clinically, it is defined by extensive, rapidly progressive and extremely painful eschar[] Clinical presentation is nonspecific in most cases and can be characterized by an initial discrepancy between severe abdominal pain and minimal clinical findings.[]

  • Tropical Phagedenic Ulcer

    ; pyoderma gangrenosum; cutaneous diphtheria; gummatous syphilis; yaws; leprosy; chromomycosis; squamous cell carcinoma; venous stasis ulcer; atypical mycobacterial infection[] Pain, comfort, date of epithelialization or eschar formation, the need for grafts, and microbiological studies also were assessed for both dressing types.[] Peptic ulcers that perforate the upper gastrointestinal tract may penetrate the pancreas, causing symptoms of pancreatitis (severe back pain) and chemical peritonitis followed[]

  • Calciphylaxis

    The main differential diagnoses include pyoderma gangrenosum, coagulopathies and arteriosclerotic ulcers.[] This is followed by necrosis, ulcers, eschar formation, and possibly gangrene.[] Two weeks following surgery, the patient developed severe respiratory distress, abdominal pain, and subsequently required transfer to the ICU.[]

  • Brown Recluse Spider Bite

    A recent biopsy showed pseudoepitheliomatous hyperplasia and pyoderma gangrenosum complicating the original injury.[] The bleb ruptures, causing necrosis in the next 3 to 4 days, followed by eschar formation between 5 and 7 days. 4 Between 7 and 14 days, the eschar falls off and leaves an[] Symptoms include severe muscle cramps, abdominal pain , weakness, and tremor.[]

  • Penile Gangrene

    Pyoderma gangrenosum presenting as Founder’s gangrene. J Urol 1990; 144: 984–986. PubMed Google Scholar 22. Paty R, Smith AD. Gangrene and Founder’s gangrene.[] It is characterized by violaceous tender areas of cutaneous plaques, necrosis, and eschar formation, mostly involving toes and fingers, but rarely the penis.[] For example, a person with gangrene of the appendix or colon would be expected to have severe abdominal pain in the vicinity of the gangrene.[]

  • Necrotizing Fasciitis

    Exceptionally, it can be precipitated by surgery alone, and this entity has been described as postsurgical pyoderma gangrenosum (PSPG).[] She was discharged well with good eschar formation from the hospital 25 days after admission. Fig. 3. Case 2.[] A previously healthy 65-year-old man with history of AOSD was referred to our hospital for persistent right lower quadrant abdominal pain for 2 days.[]

  • Mucormycosis

    Primary cutaneous mucormycosis masquerading as pyoderma gangrenosum.[] Cutaneous mucormycosis produces cellulitis that progresses to dermal necrosis and black eschar formation.[] Persistent severe abdominal pain in a patient with neutropenia should alert the clinician to the possibility of a fungal infection such as zygomycosis.[]

  • Pityriasis Lichenoides et Varioliformis

    gangrenosum , Bedsore ) Cutaneous Markers of Internal Malignancy ( Florid cutaneous papillomatosis , acanthosis nigricans , sign of Leser-Trelat ) atrophic ( Lichen sclerosus[] formation.[] (40 to 41 C), neurological signs, asthenia and impaired general state, abdominal pain, interstitial lung disease, lymphocytic myocarditis, rheumatologic manifestations and[]

  • Neonatal Purpura Fulminans

    gangrenosum Epidermolysis Vascular HSP Leukocytoclastic vasculitis Hematoma with compartment syndrome Neoplastic Leukemia Lymphoma Essential thrombocythemia Cutaneous T-cell[] In our case, cutaneous examination revealed multiple petechiae and ecchymotic patches with necrotic lesions and eschar formation.[] For those cases which require treatment, the main goal is to relieve symptoms such as joint pain, abdominal pain, or swelling.[]

  • Hematologic Disease

    Pyoderma gangrenosum. Pyoderma gangrenosum. Its most common association is with ulcerative colitis.[] Several of the most common are weakness, fatigue, shortness of breath, easy bruising and bleeding, frequent infections, enlarged lymph nodes, distended or painful abdomen[] The eschar may eventually slough or require extensive surgical debridement.[]