Possible Causes for estrogen increased Third Trimester Pregnancy This is caused by increased levels of estrogen during pregnancy. [newkidscenter.com] Meanwhile, increased estrogen and progesterone levels cause the lower esophageal sphincter (LES) to relax, making it easier for the stomach contents to go the wrong way. [wehavekids.com] Polycystic Ovary Syndrome Also, some of the male hormones may be converted to estrogen, increasing estrogen levels. Not enough progesterone is produced to balance the increased level of estrogen. [merckmanuals.com] For instance, increasing fiber intake in your diet helps promote estrogen clearance. [top10homeremedies.com] […] reduce excess body hair and acne However, estrogen increases the risk of stroke and blood clots in the legs or lungs. [merckmanuals.com] Klinefelter Syndrome Immunohistochemical stains showed an increase in estrogen and progesterone receptors in the trigone area but not in the rest of the bladder. [ncbi.nlm.nih.gov] […] or increased testosterone, and increased serum estrogen levels. [hindawi.com] Radiation exposure and diseases that increase estrogen levels, such as liver cirrhosis or the genetic disorder Klinefelter syndrome, are among the factors that raise a man's [medical-dictionary.thefreedictionary.com] Portal Cirrhosis Increased Estrogen: Increased levels of estrogen in those with cirrhosis can result in development of spider telangiectasias, as well as testicular atrophy in men End-stage [pathwaymedicine.org] […] ratio, resulting in a marked increase of systemic estrogen levels. [amboss.com] Ascites The pathogenesis of cirrhotic ascites is complex but is ultimately initiated by portal hypertension which results in the generation of increased lymph that then accumulates [pathwaymedicine.org] Malignant Neoplasm of the Testis Since elevated levels of estrogens in utero have been found to increase testicular cancer risk, firstborn sons may be at increased risk as a result of their increased exposure [onlinelibrary.wiley.com] Specifically, trisomy 21 is associated with an increased risk. Elevated estrogens in utero. Gonadal dysgenetic lesions. HIV-infected patients. [slideshare.net] Recently an increased frequency of liver tumors, mostly adenomas, has been noted in women taking oral contraceptives (OCs); the cause has been attributed to estrogens. [ncbi.nlm.nih.gov] Atrophic Vaginitis It can be a nagging psychological stress factor in women with the condition Low hormonal levels of estrogen, increases the susceptibility of urogenital and vaginal area to [dovemed.com] The thinned endometrium and increased vaginal pH level induced by estrogen deficiency predispose the vagina and urinary tract to infection and mechanical weakness. [ncbi.nlm.nih.gov] A lack of estrogen increases the pH value, rendering the body susceptible to vaginal/urinary infections. It also thins the vaginal walls, making it inelastic and dry. [dovemed.com] Liver Failure These occur when a person’s estrogen level is increased, which may happen if the liver is failing to adequately metabolize the hormone. [news-medical.net] Leydig Cell Tumor of the Testis Diagnostic Work-up Laboratory tests Hormone analysis : Testosterone is usually elevated, estrogen may be increased. LH and FSH are usually suppressed. [urology-textbook.com] Specifically, trisomy 21 is associated with an increased risk. Elevated estrogens in utero. Gonadal dysgenetic lesions. HIV-infected patients. [slideshare.net] Hepatocellular Carcinoma Exp Mol Pathol. 2017 Oct;103(2):200-203. doi: 10.1016/j.yexmp.2017.09.004. Epub 2017 Sep 20. Author information 1 Harbor UCLA Medical Center, Department of Pathology, 1000 West Carson Street, Torrance, CA 90502, United States. Electronic address: jlu3@dhs.lacounty.gov. 2 Department of Radiology, 1000 West Carson[…] [ncbi.nlm.nih.gov] Adrenocortical Carcinoma Testosterone and other androgens: increased facial and body hair, particularly in females deepened voice in females Estrogen: early signs of puberty in children enlarged breast [healthline.com] Families with Li–Fraumeni syndrome have increased risk. [youtube.com] Feminization (estrogen excess) is most readily noted in men, and includes breast enlargement, decreased libido and impotence. [youtube.com] Hydatidiform Mole In patients in low-estrogen states (perimenopause, menopause, and status postoophorectomy), pituitary hCG may be secreted in increasing amounts, although only levels between [cancer.gov] Estrogen provides negative feedback for this LH secretion and acts as a suppressing agent. [cancer.gov] Endometrial Adenocarcinoma Unopposed estrogen therapy, obesity, anovulatory cycles and estrogen-secreting neoplasms all increase the amount of unopposed estrogen and thereby increase the risk for endometrial [aafp.org] We noticed an increase of more aggressive G3 endometrioid endometrial adenocarcinomas. [ncbi.nlm.nih.gov] Because any condition that increases exposure to unopposed estrogen increases the risk of endometrial cancer, tamoxifen therapy, estrogen replacement therapy without progestin [aafp.org] Gynecomastia estrogen action Increased aromatization of androgens to estrogens Increased androgenic precursors (dehydroepiandrosterone [DHEA] and androstenedione) Increased SHBG – binds [emedicine.medscape.com] Increased estrogen production and severe hyperthyroidism can also cause the gynecomastia. [bodylogicmd.com] Gynecomastia results from an altered estrogen-androgen balance, in favor of estrogen, or from increased breast sensitivity to a normal circulating estrogen level. [6] The [emedicine.medscape.com] Myxedema 2015 ICD-9-CM Diagnosis Code 244.9 Unspecified acquired hypothyroidism 2015 Billable Thru Sept 30/2015 Non-Billable On/After Oct 1/2015 ICD-9-CM 244.9 is a billable medical code that can be used to indicate a diagnosis on a reimbursement claim, however, 244.9 should only be used for claims with a date of service on or[…] [icd9data.com] Polyostotic Fibrous Dysplasia Various endocrine diseases may present in McCune–Albright syndrome due to increased hormone production. [en.wikipedia.org] Similar mechanisms of increased intracellular cAMP likely explain essentially all of the other endocrine and nonendocrine features of MAS. [emedicine.medscape.com] A commonly used medication is letrozole, which blocks the formation of estrogen. [magicfoundation.org] Male Hypogonadism In the presence of increased estrogen production symptoms (breast tenderness and gynecomastia), a short-term trial with non-aromatizable androgens (dihydrotestosterone mesterolone [ncbi.nlm.nih.gov] Because increased estrogen levels can increase your risk of endometrial cancer, you’ll be given a combination of estrogen and progesterone if you haven’t had a hysterectomy [healthline.com] Your first line of treatment will probably be estrogen therapy if you’ve had a hysterectomy. Either a patch or pill can administer supplemental estrogen. [healthline.com] Choriocarcinoma A 25-year-old man, with a retroperitoneal bulky mass invading the posterior pancreas head, was referred to investigate and treat his rapidly advancing disease. An endoscopic ultrasonography guided-fine needle aspiration biopsy (EUS-FNAB), performed the next day, and followed by immunostaining for human chorionic[…] [ncbi.nlm.nih.gov] Androgen Insensitivity Syndrome FSH, LH/FSH ratio 2, increased response of LH to LH-RH Androgen excess: increased total testosterone and DHEA Increase estrogens from periferal conversion especially estrone [slideplayer.com] Normal or increased Luteinizing hormone Increased Increased Increased Estrogens Normal male Slightly increased Slightly increased Anatomic development External genitalia [doi.org] (P 0.05), while luteinizing hormone and follicle-stimulating hormone significantly increased (P 0.05). [ncbi.nlm.nih.gov] Estrogen Deficiency Abstract Compelling evidences suggest that increased production of osteoclastogenic cytokines by activated T cells plays a relevant role in the bone loss induced by estrogen [ncbi.nlm.nih.gov] Today, if estrogen replacement therapy is used in menopausal women, it’s usually short-term because estrogen increases the risk of certain cancers and heart disease. [wisegeek.com] Abstract Estrogen deficiency leads to marked increases in osteoclastic bone resorption, but the exact mechanism is unclear. [ncbi.nlm.nih.gov] Vaginitis Increased Estrogen Having an increased estrogen level raises your risk of a vaginal yeast infection. [diabetes.about.com] […] often occurs when estrogen levels abruptly decrease) and during the few months before menarche, when estrogen production increases. [msdmanuals.com] Usually, a marked decrease in estrogen causes vaginal thinning, increasing vulnerability to infection and inflammation. [msdmanuals.com] Vaginal Candidiasis Increased estrogen levels. [web.archive.org] […] daily (7.5 mcg of estradiol). [39] Serum estrogen is slightly increased but usually remains in the menopausal range. [emedicine.medscape.com] Yeast infections appear to occur more frequently in women with increased estrogen levels — for instance, in women who are pregnant, those taking high-dose estrogen birth control [web.archive.org] Hypogonadism Because increased estrogen levels can increase your risk of endometrial cancer, you’ll be given a combination of estrogen and progesterone if you haven’t had a hysterectomy [healthline.com] Your first line of treatment will probably be estrogen therapy if you’ve had a hysterectomy. Either a patch or pill can administer supplemental estrogen. [healthline.com] Treatment for female hypogonadism If you’re female, your treatment will involve increasing your amount of female sex hormones. [healthline.com] Osteoporosis Menopause is a foremost factor that cause lower estrogen levels and increase women’s risk for osteoporosis. [aclr.com.es] Estrogen increases the risk for stroke, and estrogen with progestin increases the risk for coronary heart disease and breast cancer (2). [doi.org] Raloxifene (Evista) is an alternative to estrogen replacement therapy. It behaves like estrogen on bone to increase bone density. [drugs.com] Urinary Tract Infection Estrogens increase the likelihood of colonization, and oral contraceptives increase the risk of bacteriuria, apparently by causing physiologic changes in the urinary tract [microbiologybook.org] Some research suggests that estrogen may help increase the number of beneficial bacteria that help fight infections. [drweil.com] After menopause, the risk for recurrent infections increases substantially. [drweil.com] Aromatase excess syndrome It has been shown that epstein barr virus is capable of increasing aromatase, favoring elevations in circulating estrogen (7, 8). [metabolichealing.com] Increased estrogen in females can cause symptoms such as irregular menstrual periods and short stature. [ghr.nlm.nih.gov] […] levels of estrogen due to elevated extraglandular aromatase activity. [orpha.net] Vulvitis Serum estrogen is slightly increased but usually remains in the menopausal range. [www1.cgmh.org.tw] […] in oral contraceptives found an increase in vaginal colonization by Candida. [csh.org.tw] Similarly, young girls who have not yet reached puberty are also at risk because they don't make adult levels of estrogen yet. [womenshealth.about.com] Cystitis Some research suggests that estrogen may help increase the number of beneficial bacteria that help fight urinary and vaginal infections. [drweil.com] For postmenopausal women with recurrent infections, topical estrogen therapy may be needed. [bumrungrad.com] And researchers at Tufts who examined bladder mast cells under an electron microscope also noticed an increased number of estrogen receptors in cells from women with IC. [womentowomen.com] Vitamin D Deficiency The complex role of estrogens in inflammation. Endocr Rev. 2007;28(5):521–74. CrossRef PubMed Google Scholar 50. [doi.org] With gestational age, liver synthetic function increases, as does the biologically active 1,25(OH)2D3 metabolite. [mdpi.com] Increased intracortical remodeling following fatigue damage. Bone. 1993;14(2):103–9. CrossRef PubMed Google Scholar 49. Straub RH. [doi.org] Acute Cystitis Estrogens increase the likelihood of colonization, and oral contraceptives increase the risk of bacteriuria, apparently by causing physiologic changes in the urinary tract [microbiologybook.org] […] inoculation spermicide – increased binding estrogen depletion – increased binding antimicrobial agents – decreased indigenous flora Facilitate Ascent catheterization (chronic [auanet.org] Vaginal estrogen may be useful for post-menopausal women who have recurrent UTIs. [auanet.org] Acute Alcohol Intoxication Major incidence of cholelithiasis is due to several factors with various pathogenesis: hypersplenism, increased level of estrogen, increased intravascular hemolysis, reduction [intechopen.com] Medications: Different medications have been found to increase a person’s risk of developing gallstones, for example, estrogen contraceptives, octreotide, and ceftriaxone. [marinahospital.com] The increased incidence in elderly men has been linked to age-related changes in the androgen-to-estrogen ratios. [emedicine.medscape.com]
