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11 Possible Causes for Exanthema, Fatigue, Systemic Autoinflammation

  • Vasculitis

    To date, several cases of systemic lupus erythematosus, Aicardi-Goutieres syndrome, familial chilblain lupus, retinal vasculopathy-cerebral leukodystrophy have been reported[ncbi.nlm.nih.gov] Aspects of disease relevant for AAV patients were: fatigue and lack of energy; visual abnormalities; neuropathy; renal impairment; arthritis, and sinusitis.[ncbi.nlm.nih.gov] […] disease include fever lasting over 5 days, bilateral congestion of the conjunctiva, erythema of the lips, buccal mucosa and the tongue, cervical lymphadenopathy, polymorphous exanthema[symptoma.com]

  • Erythema Nodosum

    Ahmet Gül, Behçet Disease, Textbook of Autoinflammation, 10.1007/978-3-319-98605-0_35, (647-665), (2019).[doi.org] Erythema nodosum is often associated with a distressing symptomatology, including painful subcutaneous nodules, polyarthropathy, and significant fatigue.[ncbi.nlm.nih.gov] […] skin syndrome, Impetigo, Boil, Carbuncle ) · Strep ( Impetigo ) · Corynebacterium ( Erythrasma ) Viral skin disease Wart · Molluscum contagiosum · Erythema infectiosum · Exanthema[wikidoc.org]

  • Cryopyrin-Associated Periodic Syndrome

    Hoffman, Autoinflammation: translating mechanism to therapy, Journal of Leukocyte Biology, 90, 1, (37-47), (2011). Keith A. Sikora and Alexei A.[doi.org] CAPS patients experience symptoms of systemic inflammation, intense fatigue and have poor quality of life.[ncbi.nlm.nih.gov] IL-1β has been shown to mediate fever, inflammation and fatigue, which all contribute to CAPS patient's decreased quality of life.[symptoma.com]

  • Sweet Syndrome

    French, Autoinflammation behind the curtain, British Journal of Dermatology, 178, 3, (581-582), (2018). Pedro Secchin, Maria K. Gomes, Danielle C.[doi.org] Systemic side effects of PCV13 include chills, fever, headache, vomiting, fatigue, arthralgia, myalgias, decreased appetite, and diarrhea, whereas its cutaneous adverse reactions[medical-dictionary.thefreedictionary.com] It is usually accompanied by symptoms of fever, fatigue or lack of energy, mouth ulcers and inflammation of the joints.[estcourtnews.co.za]

  • CINCA Syndrome

    […] autoinflammatory conditions characterized by chronic systemic inflammation due to an abnormal regulation of the innate immune system.[ncbi.nlm.nih.gov] Patients frequently complain of fatigue.[printo.it] […] to cold temperatures MWS (moderate manifestation) Recurrent or daily rash Bouts of fever Fatigue; drowsiness Joint and muscle pain Red eyes, eye inflammation Headaches Gradual[autoinflammation-reference-center-charite.de]

  • Pericarditis

    More recently, there has been evidence that the innate immune system and autoinflammation contribute to acute and recurrent pericarditis. [6, 7] Chronic idiopathic pericarditis[emedicine.com] Clinical signs include fatigue, muscle wasting, and weight loss Applies To Concato's disease Pick's disease of heart (and liver) ICD-9-CM Volume 2 Index entries containing[icd9data.com] […] complex with a key role in innate immunity) lead to overproduction of pro-inflammatory cytokines such as IL-1β, triggering different inflammatory symptoms, such as fever, exanthema[analesdepediatria.org]

  • Familial Mediterranean Fever

    Intrinsic apoptosis seemed irrelevant for confining synovial autoinflammation, but regulation through pyroptosis or the adaptive immune system remains possible. arthritis[pediatrics.aappublications.org] Pittsburgh Sleep Quality Index (PSQI), Multidimensional Assessment of Fatigue (MAF), Nottingham Health Profile (NHP), Fatigue Severity Scale (FSS), Fatigue Impact Scale (FIS[ncbi.nlm.nih.gov] Clinical differential diagnoses encompass erysipelas, erysipelas-like rashes after joint replacements, mercury exanthemas and malignant counter-parts (e.g. erysipelas melanomatosa[oatext.com]

  • Ichthyosis and Male Hypogonadism

    […] autosomal dominant systemic disorder characterized by recurrent blistering skin lesions with a dense inflammatory infiltrate and variable involvement of other tissues, including[mendelian.co] […] patients with Kallmann syndrome have either anosmia or severe hyposmia and may exhibit symptoms of associated conditions including those of congenital heart disease (eg, fatigue[emedicine.medscape.com] […] acute appendicitis 【急性中毒性表皮剥離(剥脱)】*epidermolysis acuta toxica[L] (略 EAT) 【急性洞炎】*acute sinusitis 【急性脳症】*acute encephalopathy 【急性副鼻腔炎】*acute paranasal sinusitis 【急性発疹】*acute exanthema[medo.jp]

  • Anonychia Congenita Totalis

    […] with infantile enterocolitis (AIFEC) Immunoglobulin G4-related disease Eosinophilic sinusitis Nervous system diseases Neurodegenerative diseases Alzheimer’s disease Lewy[csirnotes.com] The disorder is characterized by bruising, fatigue, anemia, low blood platelet count and enlargement of the liver and spleen, and is caused by a hereditary deficiency of the[checkrare.com] […] subitum [sixth disease] B08.20 Exanthema subitum [sixth disease], unspecified B08.21 Exanthema subitum [sixth disease] due to human herpesvirus 6 B08.22 Exanthema subitum[eicd10.com]

  • Early-Onset Sarcoidosis

    The underlying mechanisms of Blau syndrome leading to autoinflammation are still unclear, and there is currently no effective specific treatment for Blau syndrome.[readbyqxmd.com] If you have liver symptoms, they might include fever, feeling tired or fatigued, itchy skin, pain on your upper right side under your ribs.[sa-uk.org] The initial symptoms comprise a typical exanthema, with tiny round lesions that vary in colour from pale pink to tan or intense erythema.[printo.it]

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