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2,707 Possible Causes for Exanthema, Pancytopenia, Polyclonal Hyperglobulinemia

  • HIV Infection

    […] osteomalacia* Protease inhibitors with statins: myopathy Hematologic or oncologic Anemia of chronic disease Lymphoma, multiple myeloma Bone marrow infiltration (leading to pancytopenia[aafp.org] Hyperactivation is reflected in dramatic polyclonal hyperglobulinemia, only a portion of which is directed against HIV antigens;(59) bone marrow plasmacytosis;(60) heightened[hivinsite.ucsf.edu] Pancytopenia is not uncommon in advanced AIDS and bone marrow biopsies often reveal evidence of hypoplasia.[hivinsite.ucsf.edu]

  • Graft-versus-Host-Disease

    Acute cutaneous GvHD, consisting of symmetrical maculopapular exanthema with prominent acral erythema and accentuated lesions on the face and pinnae, was clinically suspected[ncbi.nlm.nih.gov] All cases had diarrhea and pancytopenia, 4 out of 5 presented with erythematous skin rashes, and 2 had cytomegalovirus colitis.[ncbi.nlm.nih.gov] DISCUSSION The characteristic cutaneous manifestations of acute GVHD, which generally occur within 3 months after BMT, include maculopapular exanthema and perifollicular papular[anndermatol.org]

    Missing: Polyclonal Hyperglobulinemia
  • Systemic Lupus Erythematosus

    A 42-year-old woman was admitted to our hospital with complaints of exanthema, arthralgia, shortness of breath, and hemoptysis.[ncbi.nlm.nih.gov] A 24-year-old man who had been diagnosed with SLE three months previously, presented with fever, rash, hallucination, and pancytopenia accompanied with hyperferritinemia and[ncbi.nlm.nih.gov] We report the case of a 44-year-old woman admitted with pancytopenia and clinical features of systemic lupus erythematosus, Sjogren's syndrome and antiphospholipid antibodies[ncbi.nlm.nih.gov]

    Missing: Polyclonal Hyperglobulinemia
  • Dyskeratosis Congenita

    One cousin had pancytopenia and the other had thrombocytopenia. The kindred displays a deficiency of glucose-6-phosphate dehydrogenase (G6PD) and a β-thalassemia trait.[jamanetwork.com] A contribution to congenital poikilodermias as well as a contribution to familial pancytopenias].[wwww.unboundmedicine.com] Approximately 50% of patients develop pancytopenia.[ncbi.nlm.nih.gov]

    Missing: Polyclonal Hyperglobulinemia
  • Malignant Histiocytosis

    Polymorphic maculopapular exanthema with hemorrhaging, ulceration and formation of crusts are observed.[lecturio.com] […] pancreas at initial presentation is exceptional, this entity should be included in the differential diagnosis of acute pancreatitis, especially when hepatosplenomegaly and pancytopenia[ncbi.nlm.nih.gov] Abstract Until recently, malignant histiocytosis was a clearly defined clinical entity marked by fever, progressive wasting, lymphadenopathy, hepatosplenomegaly, and pancytopenia[ncbi.nlm.nih.gov]

    Missing: Polyclonal Hyperglobulinemia
  • Systemic Mastocytosis

    The disease progressed rapidly and severe pancytopenia and recurrent upper gastrointestinal bleeding became the dominant problem.[ncbi.nlm.nih.gov] […] organomegaly and organ dysfunction, impairment of hematopoietic function (which may result in disruption of the blood count ranging from isolated cytopenia to more or less marked pancytopenia[orpha.net] We report the case of a 48-year old male patient who presented with hepatosplenomegaly for 12 years, yellow-brown colored maculopapular pigmentation on the skin and pancytopenia[sciforschenonline.org]

    Missing: Polyclonal Hyperglobulinemia
  • Multicentric Castleman's Disease

    We report a patient with HIV-associated multicentric Castleman's disease who had recurrent human herpesvirus-8 viremia associated with intermittent febrile exanthema and lymphadenopathy[ncbi.nlm.nih.gov] Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present.[ncbi.nlm.nih.gov] hyperglobulinemia, elevated transaminases and renal disease. 2 , 5 , 7 Dispenzieri et al. 8 analyzed the clinical spectrum of Castleman’s disease in 113 patients.[pagepress.org]

  • HIV-2 Infection

    OBJECTIVE: To determine the relative prevalence of HIV-1 and HIV-2 and to evaluate the World Health Organization testing strategy for HIV diagnosis in a low-risk population in Brazil. In addition, to assess risk factors for HIV infection. DESIGN: Sera obtained from 9885 consecutive blood donors were screened in[…][ncbi.nlm.nih.gov]

    Missing: Polyclonal Hyperglobulinemia
  • Castleman Disease

    There is often significant anemia which may be hemolytic, often reflecting pancytopenia or hemophagocytic syndrome (Stebbing 2009).[hivbook.com] The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy.[ncbi.nlm.nih.gov] , hypoalbuminemia, polyclonal hypergammaglobulinemia, leukocytosis, thrombocytosis or splenomegaly. 1,4 In contrast to the localized form, the clinical course of the multicentric[scielo.br]

  • Infectious Mononucleosis

    Amoxicillin-induced exanthema in young adults with infectious mononucleosis: Demonstration of drug-specific lymphocyte reactivity. Br J Dermatol 2002 ; 147: 1166 – 70.[oadoi.org] […] infection as an adult is a risk factor for the development of multiple sclerosis. [1, 2] Hematologic complications can include development of autoimmune hemolytic anemia, pancytopenia[emedicine.medscape.com] Timár L, Baló-Banga JM, Budai J (1987) [Infectious mononucleosis and drug exanthema].Orv Hetil 128: 1871-1874.[omicsonline.org]

    Missing: Polyclonal Hyperglobulinemia

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