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11 Possible Causes for Exanthema, Systemic Autoinflammation

  • Vasculitis

    To date, several cases of systemic lupus erythematosus, Aicardi-Goutieres syndrome, familial chilblain lupus, retinal vasculopathy-cerebral leukodystrophy have been reported[ncbi.nlm.nih.gov] […] disease include fever lasting over 5 days, bilateral congestion of the conjunctiva, erythema of the lips, buccal mucosa and the tongue, cervical lymphadenopathy, polymorphous exanthema[symptoma.com] […] include a fever persisting for at least five days (mandatory criterion) plus 4 of the following 5 features: Changes in peripheral extremities or perineal area Polymorphous exanthema[emedicine.medscape.com]

  • Erythema Nodosum

    Ahmet Gül, Behçet Disease, Textbook of Autoinflammation, 10.1007/978-3-319-98605-0_35, (647-665), (2019).[doi.org] […] skin syndrome, Impetigo, Boil, Carbuncle ) · Strep ( Impetigo ) · Corynebacterium ( Erythrasma ) Viral skin disease Wart · Molluscum contagiosum · Erythema infectiosum · Exanthema[wikidoc.org] Peterson, Oral Manifestations of Systemic Diseases and Their Treatments, Contemporary Oral Medicine, 10.1007/978-3-319-72303-7_18, (1523-1639), (2019).[doi.org]

  • Cryopyrin-Associated Periodic Syndrome

    Hoffman, Autoinflammation: translating mechanism to therapy, Journal of Leukocyte Biology, 90, 1, (37-47), (2011). Keith A. Sikora and Alexei A.[doi.org] Binstadt, Advances in the pathogenesis and treatment of systemic juvenile idiopathic arthritis, Pediatric Research, 10.1038/pr.2013.187, 75, 1-2, (176-183), (2013). T.[doi.org] Grom, Update on the pathogenesis and treatment of systemic idiopathic arthritis, Current Opinion in Pediatrics, 10.1097/MOP.0b013e32834cba24, 23, 6, (640-646), (2011).[doi.org]

  • Familial Mediterranean Fever

    Intrinsic apoptosis seemed irrelevant for confining synovial autoinflammation, but regulation through pyroptosis or the adaptive immune system remains possible. arthritis[pediatrics.aappublications.org] Clinical differential diagnoses encompass erysipelas, erysipelas-like rashes after joint replacements, mercury exanthemas and malignant counter-parts (e.g. erysipelas melanomatosa[oatext.com] […] the presence of nonpathogenic neutrophils lacking effector molecules and the widespread expression of anti-inflammatory galectin 1 in regulatory cells of the innate immune system[pediatrics.aappublications.org]

  • Sweet Syndrome

    French, Autoinflammation behind the curtain, British Journal of Dermatology, 178, 3, (581-582), (2018). Pedro Secchin, Maria K. Gomes, Danielle C.[doi.org] Krueger, Interleukin-17 Inhibition for the Treatment of Inflammatory Skin Disease, Biologic and Systemic Agents in Dermatology, 10.1007/978-3-319-66884-0_15, (133-144), (2017[doi.org]

  • CINCA Syndrome

    […] autoinflammatory conditions characterized by chronic systemic inflammation due to an abnormal regulation of the innate immune system.[ncbi.nlm.nih.gov] Keywords: Autoinflammation, Cryopyrinopathies, Urticarial rash, Aseptic meningitis, Hearing loss, IL-1 Background Cryopyrin-associated periodic syndromes (CAPS) are inherited[ncbi.nlm.nih.gov]

  • Pericarditis

    More recently, there has been evidence that the innate immune system and autoinflammation contribute to acute and recurrent pericarditis. [6, 7] Chronic idiopathic pericarditis[emedicine.com] […] complex with a key role in innate immunity) lead to overproduction of pro-inflammatory cytokines such as IL-1β, triggering different inflammatory symptoms, such as fever, exanthema[analesdepediatria.org]

  • Ichthyosis and Male Hypogonadism

    […] autosomal dominant systemic disorder characterized by recurrent blistering skin lesions with a dense inflammatory infiltrate and variable involvement of other tissues, including[mendelian.co] […] acute appendicitis 【急性中毒性表皮剥離(剥脱)】*epidermolysis acuta toxica[L] (略 EAT) 【急性洞炎】*acute sinusitis 【急性脳症】*acute encephalopathy 【急性副鼻腔炎】*acute paranasal sinusitis 【急性発疹】*acute exanthema[medo.jp] , ANTIBODY DEFICIENCY, AND IMMUNE DYSREGULATION, PLCG2-ASSOCIATED; APLAID Autoinflammation and PLCG2-associated antibody deficiency and immune dysregulation (APLAID) is an[mendelian.co]

  • Anonychia Congenita Totalis

    […] with infantile enterocolitis (AIFEC) Immunoglobulin G4-related disease Eosinophilic sinusitis Nervous system diseases Neurodegenerative diseases Alzheimer’s disease Lewy[csirnotes.com] […] subitum [sixth disease] B08.20 Exanthema subitum [sixth disease], unspecified B08.21 Exanthema subitum [sixth disease] due to human herpesvirus 6 B08.22 Exanthema subitum[eicd10.com] , antibody deficiency, and immune dysregulation syndrome, 614878 PSMB8 Autoinflammation, lipodystrophy, and dermatosis syndrome, 256040 DRD4 Autonomic nervous system dysfunction[gsdseq.ir]

  • Neonatal Inflammatory Skin and Bowel Disease 2

    Autoinflammation, LipoDystrophy, and Dermatosis syndrome (ALDD) ALDD is a systemic inflammatory condition starting within the first months of life, and comprising elevated[ojrd.biomedcentral.com] Roseola infantum or exanthema subitum – Human herpesvirus 6 or 7 infection – High fever for 3-4 days – Followed by seizures – Generalized rash (trunk to extremities, face[learn.pediatrics.ubc.ca] LipoDystrophy and Dermatosis syndrome (ALDD) Introduction Autoinflammatory diseases arise from disorders of the innate immune system[ 1 ].[ojrd.biomedcentral.com]

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