Possible Causes for excessive wrinkled skin Brittle Cornea Syndrome Type 1 wrinkled skin of palms and soles). [xpertdox.com] […] increased size of the skull), myopia (closed sightedness), epicanthus (eye folds), disproportionate tall stature, red hair, spondylolisthesis, and palmoplantar cutis laxa (excessive [xpertdox.com] […] fractures, mitral valve prolapse, neonatal hypotonia, narrowing of pulmonary valve, retinal detachment, sclerocornea, scoliosis (abnormal curving of spine), atypical scarring of skin [xpertdox.com] Autosomal Recessive Cutis Laxa Type 1A wrinkled skin Minicore myopathy Left ventricular noncompaction Mitochondrial depletion Dilatation Proptosis Skeletal dysplasia Camptodactyly Platyspondyly Joint hypermobility [mendelian.co] Definition A form of cutis laxa, a disorder characterized by an excessive congenital skin wrinkling, a large fontanelle with delayed closure, a typical facial appearance with [uniprot.org] UniProtKB/Swiss-Prot : 73 Cutis laxa, autosomal recessive, 2B: A disorder characterized by an excessive congenital skin wrinkling, a large fontanelle with delayed closure, [malacards.org] Dermatosparaxis […] with presence of excessive skin folds at the ankles and wrists Increase in palmar wrinkling Excessive bruisability with heightened risk of subcutaneous haemorrhage and hematomas [xpertdox.com] with excessive skin folds at the wrists and ankles Increased palmar wrinkling Severe bruisability with a risk of subcutaneous hematomas and haemorrhage Umbilical hernia [rarediseases.info.nih.gov] Other signs and symptoms include Dysphasia, Echolalia, Esophagitis, Excessive wrinkled skin, Aphasia, Avascular necrosis of the capital femoral epiphysis, Coxa valga, Coxa [xpertdox.com] Labile Hypertension Prednosti unosa alkohola za kardiovaskularni sistem kod .Blepharoplasty is surgery of the upper and lower eyelids where fat, excess skin, bags, pouches, and wrinkles in the [uviko.webcindario.com] Traveler's Diarrhea […] thirst, wrinkled skin, decreased urination, and dizziness or light-headedness, are present; fluid loss may have serious consequences, such as circulatory collapse and renal [web.archive.org] […] and may further aggravate dehydration; discontinuation of medication and rehydration therapy is essential if signs or symptoms of dehydration, such as dryness of mouth, excessive [web.archive.org] Dehydration Severe Dehydration (in addition to the symptoms and signals already listed): Very fussy Excessively sleepy Sunken eyes Cool, discolored hands and feet Wrinkled skin Urinates [healthychildren.org] Malignant Neoplasm of the Skin Also take care to prevent wrinkling or excessive stretching of the graft. [web.archive.org] Although this sounds simple and obvious, dermis and epidermis can appear very similar without close inspection in lighter-skinned individuals. [web.archive.org] Psychosomatic Disorder […] and other signs of aging from your face; an incision is made near the hair line and skin is pulled back and excess tissue is excised dissociative disorder dissociation so [vocabulary.com] […] disorders characterized by distortions of reality and disturbances of thought and language and withdrawal from social contact cosmetic surgery plastic surgery to remove wrinkles [vocabulary.com] Cutis Laxa Definition A disorder characterized by an excessive congenital skin wrinkling, a large fontanelle with delayed closure, a typical facial appearance with downslanting palpebral [uniprot.org] All forms of CL share the symptom of excess, loose and wrinkled skin. Most forms of CL are not associated with an augmented vulnerability, though. [symptoma.com] Both neonates had excessive skinfolds in the neck and axial regions, and wrinkled skin of the hands and feet. [nature.com] Trimalleolar Fracture In all other cases, surgery should be deferred until swelling around the joint has subsided and wrinkles have reappeared in the skin. [ncbi.nlm.nih.gov] If surgery is performed while the soft tissues are still swollen, it may be technically impossible to close the wound without excessive tension. [ncbi.nlm.nih.gov] Ehlers-Danlos Syndrome Type 4 wrinkled skin 0007392 Gingival overgrowth Gum enlargement 0000212 Gingivitis Inflamed gums Red and swollen gums [ more ] 0000230 Hemoptysis Coughing up blood 0002105 High [rarediseases.info.nih.gov] […] refer to excessive wrinkling and thinness of the skin over hands and feet, which may produce an elderly appearance. [path.upmc.edu] Redundant, almost lax skin, with excessive skin folds at wrists and ankles. Increased palmar wrinkling. [patient.info] Non-Syndromic Ocular Stickler Syndrome Type 1 […] loose, wrinkled and inelastic skin due to structural defects in the elastic fibres or abnormal maturation and secretion of proteins involved [4]. [rbht.nhs.uk] Transcript Clinical sensitivity COL4A5 ENST00000328300.6 65% [3] Elastin-related phenotypes or Cutis laxa Cutis laxa (CL) is a connective tissue disorder characterised by excessive [rbht.nhs.uk] Congenital Aural Atresia wrinkled skin Show HP:0007495 Prematurely aged appearance Show HP:0007565 Multiple cafe-au-lait spots Show HP:0007776 Partial absence of lower eyelashes Show HP:0007957 Variable [manteia.igbmc.fr] […] nasal morphology Show HP:0005280 Depressed nasal root and bridge Show HP:0005338 Sparse lateral eyebrows Show HP:0006709 Aplasia/Hypoplasia of the nipples Show HP:0007392 Excessive [manteia.igbmc.fr] Pressure Ulcer In addition, when slowly sliding down a bed or chair, friction to the outer skin layer — such as from wrinkled bedding and clothing — contribute to skin injury and ulceration [dermnetnz.org] Excessive exposure to moisture, such as sweat, blood, urine or faeces, also increases the likelihood of developing a pressure ulcer. Who is at risk of a pressure ulcer? [dermnetnz.org] Ehlers-Danlos Syndrome Periodontitis Type 1 wrinkled skin of palms and soles Increased wrinkles of palms and soles Wrinkled palms and soles Wrinkled skin of hands and feet [ more ] 0007517 Poor wound healing 0001058 [rarediseases.info.nih.gov] Redundant, almost lax skin, with excessive skin folds at wrists and ankles. Increased palmar wrinkling. [patient.info] Inguinal hernia 0000023 Intestinal perforation 0031368 Joint laxity Joint instability Lax joints Loose-jointedness Loosejointedness [ more ] 0001388 Palmoplantar cutis laxa Excessive [rarediseases.info.nih.gov] Kohlschütter-Tönz Syndrome skin of hands and feet Corneal opacity Retinal degeneration Skin rash Hepatosplenomegaly Coarse facial features Dysphagia Hyperreflexia Nevus Visual impairment Excessive [mendelian.co] skin wrinkling on dorsum of hands and fingers Ichthyosis High nonceruloplasmin-bound serum copper Multiple plantar creases Atrial septal dilatation Small, conical teeth Slender [mendelian.co] wrinkled skin Deep plantar creases Intention tremor Cortical visual impairment Generalized joint laxity Truncal ataxia Abnormality of vision Palmoplantar cutis laxa Telangiectasia [mendelian.co] Ehlers-Danlos Syndrome Kyphoscoliotic Type 1 Redundant, almost lax skin, with excessive skin folds at wrists and ankles. Increased palmar wrinkling. [patient.info] Major criteria Extreme skin fragility with congenital or postnatal skin tears. Characteristic craniofacial features. [patient.info] Viral Gastroenteritis A sunken soft spot Wrinkled skin Sunken eyes Extreme thirst Dry lips Crying without tears Cool, discolored hands and feet If your baby appears dehydrated and no doctor is [babycenter.com] Also call your doctor if your baby shows any of the classic signs of dehydration : Decreased urination (more than six hours without a wet diaper) Excessive sleepiness or fussiness [babycenter.com] Gynecomastia This allows the skin to spread out in a larger area during the healing phase, promoting an even, wrinkle-free, crease-free contour. [westlakeplasticsurgery.com] Think of it as spreading out excess tissue in a larger area so it is more likely to lay flat as opposed to being bunched up with creases and folds. [westlakeplasticsurgery.com] Wide Undermining This refers to the surgical technique of dissecting beneath the tissue to sever the attachments to the overlying skin. [westlakeplasticsurgery.com] Laron Syndrome with Immunodeficiency wrinkled skin Intracerebral periventricular calcifications Elevated hepatic transaminase Abnormal anterior chamber morphology Irregular tarsal ossification Nephrocalcinosis [mendelian.co] […] odontoid process Glycosuria Hypertonia Acidosis Jaundice Dimple chin Ivory epiphyses of the phalanges of the hand Microcornea Abnormality of dental enamel Short chin Osteopenia Excessive [mendelian.co] Autosomal Dominant Aplasia and Myelodysplasia wrinkled skin Microcephaly Gastrointestinal hemorrhage Bruising susceptibility Ptosis Stroke Carious teeth Anorexia Sporadic Premature loss of teeth Nail dystrophy Cerebellar [mendelian.co] Immunodeficiency Tics Hypertension Hepatomegaly Weight loss Neutropenia Alopecia Seizures Rare Symptoms - Less than 30% cases Vertigo Leukocytosis Oral leukoplakia Somatic mutation Excessive [mendelian.co] Disorder of the Vitreous Body It is known that excessive exposure to sunlight can cause damage to the eyes and skin, and is a contributor to cataract formation and drying, wrinkling skin. [itmonline.org] Reflex Sympathetic Dystrophy Swelling is more constant, skin wrinkles disappear, skin temperature becomes cooler, and fingernails become brittle. [medstargeorgetown.org] Swelling is more constant and skin wrinkles disappear. Skin temperature becomes cooler. Fingernails become brittle. [orthoinfo.aaos.org] Symptoms include pain and swelling, increased warmth and redness in the affected part/limb, and excessive sweating. Dystrophic: Can last three to 12 months. [medstargeorgetown.org] Skin Atrophy The thinned layer of epidermis may be a prominent feature of the microscopic appearance of the skin. aging; skin wrinkles Close-up of age spots and wrinkles on an elderly [britannica.com] […] person's facial skin. [britannica.com] Digital Vision/Thinkstock Atrophy of glands Endocrine glandular tissues may undergo atrophy when an excess of their hormonal product is present as a result of disease. [britannica.com] Shoulder-Hand Syndrome Swelling is more constant and skin wrinkles disappear. Skin temperature becomes cooler. Fingernails become brittle. [orthoinfo.aaos.org] There may be faster-than-normal nail and hair growth and excessive sweating. Stage II: Dystrophic Stage II can last 3 to 12 months. [orthoinfo.aaos.org] Pituitary Adenoma The symptoms are backache, thin skin, flushed face, weak and fragile muscles and bones, wrinkles and stretch marks, excessive hair growth, mood swings, osteoporosis of the [pharmacy-and-drugs.com] […] increased bruising or bruisability skin ulcers hypertension (high blood pressure) weight gain skin striae (lines/wrinkles/stretch marks) decreased fertility in men mood swings [pituitary.mgh.harvard.edu] excess hair growth osteoporosis rib and vertebral compression fractures Thyrotropin (TSH) secreting adenomas: weight loss increased appetite heart palpitations or irregular [pituitary.mgh.harvard.edu] Myelocerebellar Disorder wrinkled skin Esophageal stricture Ridged nail Oral leukoplakia Oral ulcer Blepharitis Premature loss of teeth Epiphora Generalized hyperpigmentation Abnormality of coagulation [mendelian.co] Pancreatic adenocarcinoma Reticular hyperpigmentation Keratoconjunctivitis Opportunistic infection Urethral stenosis Restrictive ventilatory defect Lacrimal duct stenosis Excessive [mendelian.co] […] level in blood Generalized hypopigmentation of hair Gastric ulcer Split nail Pterygium of nails Brittle scalp hair Fragile teeth Abnormal leukocyte morphology Reticulated skin [mendelian.co] Lipoma of Buttock Excision, excessive skin and subcutaneous tissue (including lipectomy); abdomen infraumbilical panniculectomy [documentation required] [not covered for aesthetic operations [aetna.com] for acne scarring, fine wrinkling, rhytids, general keratosis); segmental, face; or regional, other than face 15788 - 15793 Chemical peel 15820 - 15823 Blepharoplasty 15830 [aetna.com] Hoyeraal-Hreidarsson Syndrome wrinkled skin Generalized hyperpigmentation Generalized hypopigmentation of hair Hypertonia Nail dystrophy Oral leukoplakia Premature graying of hair Sparse scalp hair Ventriculomegaly [dovemed.com] Intrauterine growth retardation Microcephaly Thrombocytopenia Frequently present symptoms in 30-79% of the cases: Abnormality of coagulation Anemia Cerebral cortical atrophy Excessive [dovemed.com] Prolapse […] and glabella wrinkles. [ncbi.nlm.nih.gov] After measuring the redundant upper eyelid skin, the excess skin was excised. The orbital part of the orbicularis oculi muscle was identified and split longitudinally. [ncbi.nlm.nih.gov] The aim of this study was to introduce a technique of dividing forehead depressor muscles with a subbrow excision for improvement of brow ptosis or redundant upper eyelid skin [ncbi.nlm.nih.gov]
