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250 Possible Causes for Exertional Dyspnea, Hypoxia, Medication Noncompliance

  • Asthma

    A meta-analysis by DiMatteo et al [ 50 ] revealed that patients with a chronic disease and depression were three times more likely to be noncompliant with medical treatment[dx.doi.org] A 62-year-old man with asthma presented with a 1-month history of wheezing and exertional dyspnea.[ncbi.nlm.nih.gov] Vasoconstriction due to alveolar hypoxia also contributes to this mismatch. Vasoconstriction is also considered an adaptive response to ventilation/perfusion mismatch.[emedicine.medscape.com]

  • Pulmonary Edema

    ) Patient noncompliance with medications (eg, diuretics) Severe anemia Sepsis Thyrotoxicosis Myocarditis Myocardial toxins (eg, alcohol, cocaine, chemotherapeutic agents such[emedicine.com] High altitude pulmonary edema (HAPE) is a form of high altitude illness characterized by cough, dyspnea upon exertion progressing to dyspnea at rest and eventual death, seen[ncbi.nlm.nih.gov] RESULTS: Compared with control subjects, numerous hypoxia-related genes were up-regulated in patients with acute HAPE.[ncbi.nlm.nih.gov]

  • Chronic Obstructive Pulmonary Disease

    noncompliance, cardiac ischemia, abnormal heart rhythms, kidney failure, pulmonary emboli, hypertension, and infections.[13] Treatment efforts are directed towards decreasing[en.wikipedia.org] According to the history of chronic cough and exertional dyspnea, he was treated with inhaled corticosteroids for COPD.[ncbi.nlm.nih.gov] Presence of chronic hypoxia or cor pulmonale.[patient.info]

  • Cor Pulmonale

    Acute Precipitating Factors Include (1) excessive Na intake, (2) noncompliance with heart failure medications, (3) acute MI (may be silent), (4) exacerbation of hypertension[accessmedicine.mhmedical.com] The patient developed progressive exertional dyspnea, with clinical and laboratory findings of right-sided heart failure and pulmonary hypertension.[ncbi.nlm.nih.gov] The first cause of increased PVR is chronic long-standing alveolar hypoxia which induces pulmonary vascular remodeling.[ncbi.nlm.nih.gov]

  • Acute Respiratory Distress Syndrome

    noncompliance, cardiac ischemia, abnormal heart rhythms, kidney failure, pulmonary emboli, hypertension, and infections.[13] Treatment efforts are directed towards decreasing[en.wikipedia.org] […] on exertion followed by dyspnea at rest Hypoxia; PaO 2 /FIO 2 300 mm Hg Often sepsis and MODS ( JAMA 2016;315:788 ) Respiratory dysfunction and physical disability may persist[pathologyoutlines.com] Acute respiratory distress syndrome (ARDS) is a syndrome of noncardiogenic pulmonary edema and hypoxia that accompanies up to 30% of deaths in pediatric intensive care units[ncbi.nlm.nih.gov]

  • Pulmonary Embolism

    DOACs do not require monitoring, and noncompliance will not be readily apparent. Direct oral anticoagulants.[clevelandclinicmeded.com] Dyspnea may be absent or occur only with exertion. The onset of dyspnea may occur over seconds to days. Orthopnea occurs with PE as well as heart failure.[ncbi.nlm.nih.gov] Hypoxia is an independent predictor of both right ventricular dysfunction and 30-day mortality in these patients.[ncbi.nlm.nih.gov]

  • Pulmonary Hypertension

    […] pressure, including residual LV outflow tract obstruction; elevated LV end-diastolic pressure caused by a small, hypertrophied LV; endocardial fibroelastosis; and a small, noncompliant[doi.org] A 58-year-old woman was referred to our hospital with a chief complaint of exertional dyspnea.[ncbi.nlm.nih.gov] […] hypertension on chronic exposure to hypoxia.[doi.org]

  • Pulmonary Fibrosis

    Evaluation of sample size and power for analyses of survival with allowance for nonuniform patient entry, losses to follow-up, noncompliance, and stratification.[doi.org] A 71-year-old man developed exertional dyspnea and was diagnosed with IPF.[ncbi.nlm.nih.gov] VEGF-A receptors and co-receptors were differentially expressed by hypoxia and hyperoxia.[ncbi.nlm.nih.gov]

  • Pneumothorax

    noncompliance, cardiac ischemia, abnormal heart rhythms, kidney failure, pulmonary emboli, hypertension, and infections.[13] Treatment efforts are directed towards decreasing[en.wikipedia.org] A good skill in lung ultrasound is advantageous in the management of intraoperative hypoxia, particularly for prompt diagnosis of pneumothorax.[ncbi.nlm.nih.gov] Hypoxia and hypotension are characteristic of tension pneumothorax.[symptoma.com]

  • Graves Disease

    The results of the study imply that optic nerve involvement is more likely to occur in association with noncompliant, fibrotic muscle than with more supple muscle of the same[ncbi.nlm.nih.gov] dyspnea.[casesjournal.biomedcentral.com] We aim to study the expression of PDGF-BB, hypoxia inducible factor (HIF)-1α and C-C motif chemokine receptor (CCR)-2 in peripheral blood of patients with GD and explore its[ncbi.nlm.nih.gov]

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