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15 Possible Causes for Exertional Syncope, patients possibly clinically asymptomatic, Variable Expressivity

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  • Orthostatic Hypotension

    We furthermore calculated within participant variability in SBP related to postural change, expressed as coefficient of variation.[ncbi.nlm.nih.gov] Childhood: Children with DBH deficiency have markedly reduced exercise capacity, perhaps because of hypotension engendered by physical exertion.[ncbi.nlm.nih.gov] These findings suggest that clinically asymptomatic orthostatic hypotension in Parkinson's disease patients may acutely worsen neuropsychological performances with possible[ncbi.nlm.nih.gov]

  • Asthma

    Asthma is a complex disorder that displays heterogeneity and variability in its clinical expression both acutely and chronically.[ncbi.nlm.nih.gov] In years to come it may be possible to identify patients with asymptomatic asthma and hence underlying inflammation by using more sensitive tests (eg impulse oscillometry[patient.info] The effect size is a dimensionless variable expressing the standardized difference (i.e., the mean difference divided by standard deviation) between, in our study, the mean[dx.doi.org]

  • Aortic Valve Disorder

    Continuous variables are expressed as mean SD. Results No patients were excluded from the analysis due to poor image quality.[cardiovascularultrasound.biomedcentral.com] A proportion of patients develop syncope on exertion, while exertional dyspnoea and other symptoms of heart failure occur late in the disease.[gponline.com] Clinical Features Symptoms Aortic valve stenosis (AVS) is a slowly progressive disease, and not all affected patients report symptoms.[emedicine.medscape.com]

  • Mitral Valve Prolapse

    This may represent two stages in disease development, variable expression, or perhaps genetic heterogeneity.[ncbi.nlm.nih.gov] Historically, the term mitral valve prolapse syndrome has been applied to MVP associated with palpitations, atypical precordial pain, dyspnea on exertion, low body mass index[en.wikipedia.org] patients in experienced surgical centers. 2 Editorial p 768 Clinical Perspective p 804 Comprehensive echocardiographic evaluation of MR has made it possible to diagnose the[circ.ahajournals.org]

  • Brugada Syndrome

    Seven relatives also carry the mutation and showed a Brugada syndrome with an incomplete and variable expression.[ncbi.nlm.nih.gov] There was no history of exertional syncope or post-exertional syncope. He had a normal exam in the ED. Here is the ECG again: Is it type 2 Brugada pattern?[hqmeded-ecg.blogspot.com] CONCLUSION: Drug-induced BS has a good prognosis if asymptomatic; however, SCD is possible.[ncbi.nlm.nih.gov]

  • Arrhythmogenic Right Ventricular Dysplasia

    The disease is inherited as an autosomal dominant trait with incomplete penetrance and variable expressivity.[ncbi.nlm.nih.gov] All patients are at risk of sudden death, particularly during exertion.[orpha.net] The patient was asymptomatic and the clinical relevance of this finding would be raised in case a possible differential diagnosis of right heart overload should be necessary[ncbi.nlm.nih.gov]

  • Cardiomyopathy

    The disorder is thought to be inherited in an autosomal dominant fashion with variable penetrance and variable expressivity.[emedicine.com] […] dyspnea, angina, syncope, sudden death Systolic murmur mitral regurgitation murmur, S4 Bifid carotid pulse with a brisk upstroke and rapid downstroke Exertional dyspnea and[merckmanuals.com] […] findings Very variable, many patients remain asymptomatic Exercise-induced ventricular arrhythmias palpitations , syncope , possibly sudden cardiac death Atypical chest pain[amboss.com]

  • Uterine Fibroid

    In several studies, p53 had variable expression profiles when comparing leiomyosarcoma to leiomyoma variants.[healthcare-communications.imedpub.com] , syncopal episodes, pulmonary embolism, and sudden death [ 15 – 17 ].[cardiovascularultrasound.biomedcentral.com] Summary of Recommended Treatment Options for Uterine Fibroids Patient characteristics Treatment options Asymptomatic women Clinical surveillance 4 Infertile women with distorted[aafp.org]

  • Familial Isolated Dilated Cardiomyopathy

    Variable expressivity.[renalandurologynews.com] As affected children age, they may experience chest pain or discomfort, irregular heartbeats, dizziness or fainting episodes (syncope) usually upon heavy exertion, and, eventually[rarediseases.org] Flow diagram with steps in clinical assessment of patients with a possible genetic cause of DCM. Symptomatic family members.[renalandurologynews.com]

  • Athletic Heart Syndrome

    Intraobserver variability was tested from blinded measurements made on the same tracings, 6 months apart, by one observer (A.P.).[circ.ahajournals.org] Personal history of exertional chest pain and/or syncope.[aafp.org] Among the many alternative causes are episodes of isolated arrhythmias which degenerated into lethal VF and asystole, and various unnoticed, possibly asymptomatic cardiac[en.wikipedia.org]

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