Exposure-to-benzene: Causes & Reasons

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Possible Causes for exposure to benzene

Leukemia

[…] treatment) smoking and other exposure to benzene, a chemical used in manufacturing that's also found in cigarette smoke having a blood disorder or some genetic conditions [nhs.uk]

Exposure to certain chemicals Being exposed to certain chemicals has been linked with some types of leukemia. For example, exposure to benzene is a risk factor for AML. [urmc.rochester.edu]

This includes earlier exposure to chemotherapy, Down’s syndrome and other genetic disorders, exposure to benzene and other chemicals, exposure to radiation therapy etc. [news-medical.net]

Aplastic Anemia

Doctors have also identified some of the possible causes of this immune system response, including: exposure to benzene, a chemical used to make plastics, synthetic fibers [medicalnewstoday.com]

Aplastic anemia can be caused by: Use of certain drugs or exposure to toxic chemicals (such as chloramphenicol, benzene) Exposure to radiation or chemotherapy Autoimmune disorders [nlm.nih.gov]

dyes, detergents, and pesticides insecticide exposure nonviral hepatitis pesticide exposure medications, such as chemotherapy drugs or chloramphenicol hepatitis pregnancy [medicalnewstoday.com]

Myelodysplasia

Exposure to environmental/occupational hazards. Long-term exposure to benzene, tobacco smoke, insecticides, and other toxins may increase the risk of developing MDS. [cancer.net]

[…] to benzene, pesticides, organic solvents Also inherited hematological conditions (e.g. [pathologyoutlines.com]

vitamin B12, folate, copper), toxic exposures (i.e., benzene, zinc, heavy metals, ethanol), pharmaceutical side effect (i.e., recent chemotherapy, growth factor stimulation [clinicaladvisor.com]

Multiple Myeloma

Exposure to radiation is thought to be a possible cause, as is exposure to benzene and other solvents. [merckmanuals.com]

Pancreatic Adenocarcinoma

In this case report we detail the treatment of a patient with pancreatic ductal adenocarcinoma and a solitary liver metastasis who received nine cycles of FOLFIRINOX therapy with favourable response. The patient subsequently underwent synchronous distal pancreatectomy and hepatectomy with an R0 resection[…] [ncbi.nlm.nih.gov]

Chronic Phase of Chronic Myeloid Leukemia

The major risk factors for CML include occupational exposure to benzene and high doses of ionizing radiation[ 4 ], which was evidenced by the 20- to 25-fold increased incidence [bmcresnotes.biomedcentral.com]

[…] to industrial chemicals like benzene over a long period of time, or exposure to certain types of chemotherapy to treat other cancers. [leukaemiaqld.org.au]

These include exposure to: radiation — very high doses of radiation, either accidentally (nuclear accident) or therapeutically (to treat other cancers) chemicals — exposure [leukaemiaqld.org.au]

Benzene Poisoning

[…] of exposure to benzene. [ncbi.nlm.nih.gov]

Benzene exposure typically takes place via inhalation, ingestion or dermal absorption. [benzeneweb.com]

’s exposure to benzene. [seegerweiss.com]

Toxic Effect of Benzene

Exposure to toxic chemicals such as benzene can cause serious health problems. The following are some effects associated with benzene exposure: 1. [madeksholaw.com]

’s exposure to benzene. [seegerweiss.com]

There was a significant correlation between individual benzene exposure level and blood benzene (rs 0.193, P [ncbi.nlm.nih.gov]

Common Cold

Hirsch et al. (1999) reported significant associations of NO 2, carbon monoxide, and benzene with bronchitis and morning cough but not with allergy-associated end points. [ncbi.nlm.nih.gov]

A few studies using traffic counts or proximity to street as exposure proxy found positive associations with sensitization and allergy-related symptoms ( Nicolai et al. 2003 [ncbi.nlm.nih.gov]

Acute Myeloid Leukemia

[…] has confirmed earlier suspicions that benzene exposure could result in a number of other types of leukemia. [cleanwaterpartners.org]

Benzene is also found in certain industrial settings; however, the strict regulation of its use has decreased benzene exposure in the workplace. [lls.org]

Radiation exposure increases the risk of AML. However, the main known causes of acute leukemia are exposure to high levels of radiation, benzene, or both. [medicalnewstoday.com]

Anemia

Some factors that may be involved with bone marrow damage and that can lead to aplastic anemia include: Exposure to toxic substances like arsenic, benzene (found in gasoline [labtestsonline.org]

Iron Deficiency

Some factors that may be involved with bone marrow damage and that can lead to aplastic anemia include: Exposure to toxic substances like arsenic, benzene (found in gasoline [labtestsonline.org]

Essential Hypertension

However, there are some factors that increases the risk of developing the cancer such as exposure to radiation and chemicals like benzene, cigarette smoking, hair dyes, family [pchrd.dost.gov.ph]

Thrombocytopenia

Similarly, excessive radiation, exposure to certain chemicals (such as benzene), or drugs used in cancer chemotherapy decrease the production of platelets. [britannica.com]

We also see that exposure to toxic chemicals, like benzene, which is a common chemical used in many manufacturing processes, can damage bone marrow, as well as some types [study.com]

Myeloproliferative Disease

Categorical analyses showed no increased risk of CML or MPD with benzene exposure. [ncbi.nlm.nih.gov]

Environmental exposure — intense radiation exposure or exposure to benzene may increase risk. Gender — men are slightly more at risk. [hillman.upmc.com]

RESULTS: Benzene exposures were low, and mean average exposure intensity for CML cases was 0.3 ppm and for MPD cases 0.17 ppm. [ncbi.nlm.nih.gov]

Secondary Myelofibrosis

Chemical solvent (20%): Long-term exposure to benzene, carbon tetrachloride and other organic solvents, in 1941 Rawson et al reported 5 cases of long-term exposure to benzene [healthfrom.com]

Long-term exposure to high levels of benzene or very high doses of ionising radiation may increase the risk of primary myelofibrosis in a small number of cases. [slideshare.net]

[…] to certain industrial chemicals, such as toluene and benzene Exposure to high levels of radiation What are the symptoms of myelofibrosis? [aamds.org]

Acute Lymphoblastic Leukemia Type L1

However, occupational exposure to benzene directly in children has never been reported. [journals.plos.org]

In animals, exposure to benzene and other chemicals can cause leukemia. [wiki.clinicalflow.com]

Avoidance of maternal benzene exposure during pregnancy might contribute to a decrease in the risk of childhood ALL. [journals.plos.org]

Refractory Anemia with Excess Blasts in Transformation

Exposure to radiation such as in the presence of an atomic bomb or nuclear reactors. Exposure to benzene and chemicals used in the production of rubber and petroleum. [syndromespedia.com]

Better recognised correlations are the late consequences of cytotoxic chemotherapy and ionising radiation with both high and low concentration of exposure to benzene injurious [cmej.org.za]

 Environmental or occupational exposure (e.g., benzene)  Tobacco •Aplastic anaemia •PNH •Polycythemia vera 6. [slideshare.net]

Acute Leukemia

exposure among more recent births, and children with AML may have increased benzene exposure at birth. [ncbi.nlm.nih.gov]

Exposure to chemical called benzene at work increases the risk of developing ALL. [sppirx.com]

Exposure to benzene increases the risk of developing AML. [oncolink.org]

Contact Dermatitis

[…] in very sensitive individuals. 73 Figure 36: Skeletal structures of dihydric benzenes (benzene rings with two hydroxyl groups). [telemedicine.org]

Therefore, one should soak with cool water in the field as soon as contact with Anacardiaceae is suspected. 73 Beware, exuberant bathing may increase the area of exposure [telemedicine.org]

Acute Monocytic Leukemia

Benzene is also found in certain industrial settings; however, the strict regulation of its use has decreased benzene exposure in the workplace. [lls.org]

These include: previous chemotherapy or radiotherapy exposure to very high levels of radiation (including previous radiotherapy treatment) exposure to benzene – a chemical [nhs.uk]

Researchers have identified potential risk factors, including: Repeated exposure to the chemical benzene, which damages the DNA of normal marrow cells. [lls.org]

Non-Hodgkin Lymphoma

benzene exposure and non-Hodgkin lymphoma (NHL) to varying exposure assessment methods. [ncbi.nlm.nih.gov]

Lymphomas and occupational benzene exposure. Lancet, 1:1394-1395. VINEIS, P., 1996. [scielosp.org]

[…] to benzene & polychlorinated biphenyls (PCBs). [physio-pedia.com]

Alzheimer Disease

Also, solvents, pesticides and EMF are categories that have too wide an exposure, including exposures with highly different biological effects (e.g., benzene and toluene, [ncbi.nlm.nih.gov]

More specific definition of exposure should also be considered in research. [ncbi.nlm.nih.gov]

Myelofibrosis

Long-term exposure to high levels of benzene or very high doses of ionising radiation may increase the risk of primary myelofibrosis in a small number of cases. [slideshare.net]

[…] to certain industrial chemicals, such as toluene and benzene Exposure to high levels of radiation Symptoms Common symptoms include: Abdominal fullness, pain or feeling full [aamds.org]

[…] to certain industrial chemicals, such as toluene and benzene Exposure to high levels of radiation What are the symptoms of myelofibrosis? [aamds.org]

Chromosome Y Structural Anomaly

"Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidy". Environ. Health Perspect. 118 (6): 833–9. doi : 10.1289/ehp.0901531. PMC 2898861. [ipfs.io]

[…] to benzene, [7] insecticides, [8] [9] and perfluorinated compounds. [10] Increased aneuploidy is often associated with increased DNA damage in spermatozoa. [en.wikipedia.org]

[…] to benzene, [6] insecticides, [7] [8] and perfluorinated compounds. [9] Increased aneuploidy is often associated with increased DNA damage in spermatozoa. [ipfs.io]

Anxiety Disorder

The most common exposure was to the aromatic and halogenated hydrocarbons (eg, toluene, xylene, benzene, and trichloroethylene). [web.archive.org]

Additionally, some subjects reported secondary exposure to other chemicals (eg, hydrogen sulfide). [web.archive.org]

Refractory Anemia with Excess Blasts

vitamin B12, folate, copper), toxic exposures (i.e., benzene, zinc, heavy metals, ethanol), pharmaceutical side effect (i.e., recent chemotherapy, growth factor stimulation [clinicaladvisor.com]

Exposure to radiation such as in the presence of an atomic bomb or nuclear reactors. Exposure to benzene and chemicals used in the production of rubber and petroleum. [syndromespedia.com]

[…] to benzene, petroleum products, fertilizers, pesticides or chemicals used in the rubber industry smoking cigarettes Being treated for certain types of cancer can also increase [cancer.ca]

Spontaneous Abortion

Exposure to mercury from the use of dental amalgam, to ethanol based disinfectant containing 0.25% benzene or to other solvents did not increase the risk. [ntnu.no]

30 years the dentists had a 2.4 times higher odds ratio (95% confidence interval: 1.0–5.4) than teachers but it was not possible to link this to a specific occupational exposure [ntnu.no]

Chronic Laryngitis

A study conducted in China compared 300 workers exposed to benzene, toluene, or both, to 130 workers from a control group without exposure, and found a higher prevalence of [scielo.br]

The exposure periods were: 2 years (1), 5 years (1), 8 years (1), 11 years (1), 12 years (1), 14 years (5), 17 years (1), and 24 years (1). [scielo.br]

The study participants were exposed to the following chemical agents: insecticides (7); toluene (1); toluene, benzene, and trichloroethylene (1); acetone, turpentine, and [scielo.br]

Crack Ingestion

Gasoline contains benzene and other additives that may cause future health problems after repeated, high-level exposures. [atsdr.cdc.gov]

Repeated exposure to very high levels of gasoline can cause poor appetite, weakness, and even brain or kidney damage. [atsdr.cdc.gov]