Exposure to Benzene: Causes & Reasons

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Possible Causes for Exposure to Benzene

Leukemia

[…] treatment) smoking and other exposure to benzene, a chemical used in manufacturing that's also found in cigarette smoke having a blood disorder or some genetic conditions [nhs.uk]

This includes earlier exposure to chemotherapy, Down’s syndrome and other genetic disorders, exposure to benzene and other chemicals, exposure to radiation therapy etc. [news-medical.net]

But some things can increase your risk of getting AML, including: previous chemotherapy or radiotherapy exposure to very high levels of radiation (including previous radiotherapy [nhs.uk]

Myelodysplasia

Exposure to environmental/occupational hazards. Long-term exposure to benzene, tobacco smoke, insecticides, and other toxins may increase the risk of developing MDS. [cancer.net]

[…] to benzene, pesticides, organic solvents Also inherited hematological conditions (e.g. [pathologyoutlines.com]

Secondary bone marrow disorders include nutritional deficiencies (i.e., vitamin B12, folate, copper), toxic exposures (i.e., benzene, zinc, heavy metals, ethanol), pharmaceutical [clinicaladvisor.com]

Aplastic Anemia

Doctors have also identified some of the possible causes of this immune system response, including: exposure to benzene, a chemical used to make plastics, synthetic fibers [medicalnewstoday.com]

Other causes include Infection with viruses such as parvovirus, Epstein Barr virus, and cytomegalovirus Radiation exposure Toxins (such as benzene) Chemotherapy drugs and [msdmanuals.com]

Known causes include exposure to chemicals (for example, benzene, toluene in glues, insecticides, solvents), drugs (for example, chemotherapy drugs, gold, seizure medications [medicinenet.com]

Benzene Poisoning

Albumin adducts of benzene derivatives can be used to measure longer term exposure. [symptoma.com]

Benzene exposure typically takes place via inhalation, ingestion or dermal absorption. [benzeneweb.com]

[…] of exposure to benzene. [ncbi.nlm.nih.gov]

Multiple Myeloma

Exposure to radiation is thought to be a possible cause, as is exposure to benzene and other solvents. [merckmanuals.com]

Chronic Phase of Chronic Myeloid Leukemia

The major risk factors for CML include occupational exposure to benzene and high doses of ionizing radiation[ 4 ], which was evidenced by the 20- to 25-fold increased incidence [bmcresnotes.biomedcentral.com]

[…] to industrial chemicals like benzene over a long period of time, or exposure to certain types of chemotherapy to treat other cancers. [leukaemiaqld.org.au]

These include exposure to: radiation — very high doses of radiation, either accidentally (nuclear accident) or therapeutically (to treat other cancers) chemicals — exposure [leukaemiaqld.org.au]

Pancreatic Adenocarcinoma

In this case report we detail the treatment of a patient with pancreatic ductal adenocarcinoma and a solitary liver metastasis who received nine cycles of FOLFIRINOX therapy with favourable response. The patient subsequently underwent synchronous distal pancreatectomy and hepatectomy with an R0 resection[…] [ncbi.nlm.nih.gov]

Acute Myeloid Leukemia

[…] has confirmed earlier suspicions that benzene exposure could result in a number of other types of leukemia. [cleanwaterpartners.org]

Benzene is also found in certain industrial settings; however, the strict regulation of its use has decreased benzene exposure in the workplace. [lls.org]

Radiation exposure increases the risk of AML. However, the main known causes of acute leukemia are exposure to high levels of radiation, benzene, or both. [medicalnewstoday.com]

Toxic Effect of Benzene

There was a significant correlation between individual benzene exposure level and blood benzene (rs=0.193, P [ncbi.nlm.nih.gov]

Exposure to toxic chemicals such as benzene can cause serious health problems. The following are some effects associated with benzene exposure: 1. [madeksholaw.com]

’s exposure to benzene. [seegerweiss.com]

Acute Monocytic Leukemia

Benzene is also found in certain industrial settings; however, the strict regulation of its use has decreased benzene exposure in the workplace. [lls.org]

Radiation exposure increases the risk of AML. However, the main known causes of acute leukemia are exposure to high levels of radiation, benzene, or both. [medicalnewstoday.com]

These include: previous chemotherapy or radiotherapy exposure to very high levels of radiation (including previous radiotherapy treatment) exposure to benzene – a chemical [nhs.uk]

Secondary Myelofibrosis

Chemical solvent (20%): Long-term exposure to benzene, carbon tetrachloride and other organic solvents, in 1941 Rawson et al reported 5 cases of long-term exposure to benzene [healthfrom.com]

Long-term exposure to high levels of benzene or very high doses of ionising radiation may increase the risk of primary myelofibrosis in a small number of cases. [slideshare.net]

[…] to certain industrial chemicals, such as toluene and benzene Exposure to high levels of radiation What are the symptoms of myelofibrosis? [aamds.org]

Acute Leukemia

exposure among more recent births, and children with AML may have increased benzene exposure at birth. [ncbi.nlm.nih.gov]

[…] treatment) smoking and other exposure to benzene, a chemical used in manufacturing that's also found in cigarette smoke having a blood disorder or some genetic conditions [nhs.uk]

Exposure to chemical called benzene at work increases the risk of developing ALL. [sppirx.com]

Chromosome Y Structural Anomaly

"Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidy". Environ. Health Perspect. 118 (6): 833–9. doi : 10.1289/ehp.0901531. PMC 2898861. [ipfs.io]

[…] to benzene, [7] insecticides, [8] [9] and perfluorinated compounds. [10] Increased aneuploidy is often associated with increased DNA damage in spermatozoa. [en.wikipedia.org]

[…] to benzene, [6] insecticides, [7] [8] and perfluorinated compounds. [9] Increased aneuploidy is often associated with increased DNA damage in spermatozoa. [ipfs.io]

Refractory Anemia with Excess Blasts

Exposure to radiation such as in the presence of an atomic bomb or nuclear reactors. Exposure to benzene and chemicals used in the production of rubber and petroleum. [syndromespedia.com]

[…] to benzene, petroleum products, fertilizers, pesticides or chemicals used in the rubber industry smoking cigarettes Being treated for certain types of cancer can also increase [cancer.ca]

Refractory Anemia with Excess Blasts in Transformation

Exposure to radiation such as in the presence of an atomic bomb or nuclear reactors. Exposure to benzene and chemicals used in the production of rubber and petroleum. [syndromespedia.com]

Better recognised correlations are the late consequences of cytotoxic chemotherapy and ionising radiation with both high and low concentration of exposure to benzene injurious [cmej.org.za]

 Environmental or occupational exposure (e.g., benzene)  Tobacco •Aplastic anaemia •PNH •Polycythemia vera 6. [slideshare.net]

Malignant Parametrium Neoplasm

[…] to benzene at their workplaces.[15] Cancer related to one's occupation is believed to represent between 2–20% of all cases.[16] Most cancer deaths caused by occupational [en.wikipedia.org]

[…] to develop cancer.[28] Common occupational carcinogens include:[29] arsenic asbestos benzene beryllium cadmium chromium ethylene oxide nickel Plutonium Lifestyle[edit] Many [en.wikipedia.org]

[…] workplace.[15] Millions of workers run the risk of developing cancers such as lung cancer and mesothelioma from inhaling asbestos fibers and tobacco smoke, or leukemia from exposure [en.wikipedia.org]

Childhood Esophageal Cancer

Residential Proximity to Heavy-Traffic Roads, Benzene Exposure, and Childhood Leukemia-The GEOCAP Study, 2002–2007. [frm.org]

Myelofibrosis

Long-term exposure to high levels of benzene or very high doses of ionising radiation may increase the risk of primary myelofibrosis in a small number of cases. [slideshare.net]

[…] to certain industrial chemicals, such as toluene and benzene Exposure to high levels of radiation Symptoms Common symptoms include: Abdominal fullness, pain or feeling full [aamds.org]

[…] to certain industrial chemicals, such as toluene and benzene Exposure to high levels of radiation What are the symptoms of myelofibrosis? [aamds.org]

EPN Poisoning

Further evaluation of susceptibility for hematotoxicity and hematological malignancy among workers with a history of occupational exposure to benzene is warranted. [cancerres.aacrjournals.org]

This is the first report that provides evidence of human susceptibility to benzene-related disease. [cancerres.aacrjournals.org]

Myeloproliferative Disease

Categorical analyses showed no increased risk of CML or MPD with benzene exposure. [ncbi.nlm.nih.gov]

An association between benzene exposure and myeloproliferative disease was established, suspicious for an occupational disease. [ncbi.nlm.nih.gov]

Environmental exposure — intense radiation exposure or exposure to benzene may increase risk. Gender — men are slightly more at risk. [hillman.upmc.com]

Acute Myelomonocytic Leukemia

Radiation exposure increases the risk of AML. However, the main known causes of acute leukemia are exposure to high levels of radiation, benzene, or both. [medicalnewstoday.com]

These include: previous chemotherapy or radiotherapy exposure to very high levels of radiation (including previous radiotherapy treatment) exposure to benzene – a chemical [nhs.uk]

[…] to benzene ). [amboss.com]

Petroleum Distillates Poisoning

Lymphomas and occupational benzene exposure. Lancet 1979; i: 1394–5. CrossRef Google Scholar Vigliani EC, Forni A. Benzene and leukaemia. Environ Res 1976; 11: 122–7. [link.springer.com]

exposure Supportive Care If intubated consider FASTHUGSINBEDPlease Investigations Screening: 12 lead ECG, BSL, Paracetamol level Specific: Serial ECGs and continuous cardiac [lifeinthefastlane.com]

Hematologic Prolonged exposure to certain aromatic hydrocarbons (especially benzene) can lead to an increased risk of aplastic anemia, multiple myeloma, and acute myelogenous [emedicine.medscape.com]

Toluene Poisoning

Often toluene exposure is concomitant with exposure to benzene and, as both substances are to a certain extent, metabolized by the same enzymes, the report of their relative [dd-database.org]

exposure Supportive Care If intubated consider FASTHUGSINBEDPlease Investigations Screening: 12 lead ECG, BSL, Paracetamol level Specific: Serial ECGs and continuous cardiac [lifeinthefastlane.com]

[…] to toluene occurs there is usually simultaneous exposure to several other chemicals. [4] Often toluene exposure occurs in conjunction with benzene and since they are to some [en.wikipedia.org]

Acute Lymphoblastic Leukemia Type L1

Exposure to a chemical called benzene at work increases the risk of developing ALL. [cancerresearchuk.org]

In animals, exposure to benzene and other chemicals can cause leukemia. [wiki.clinicalflow.com]

Exposure to benzene may occur in petrol, chemical, pharmaceutical and rubber industries. Benzene is also used in shoe production and the printing industry. [cancerresearchuk.org]

A more persistent form of aplastic anemia is caused by long-term exposure to benzene fumes (a constituent of gasoline), exposure to insecticides, or exposure to a moderate [nmihi.com]

Aplastic anemia can be caused by: Use of certain drugs or exposure to toxic chemicals (such as chloramphenicol, benzene) Exposure to radiation or chemotherapy Autoimmune disorders [medlineplus.gov]

Other causes include Infection with viruses such as parvovirus, Epstein Barr virus, and cytomegalovirus Radiation exposure Toxins (such as benzene) Chemotherapy drugs and [msdmanuals.com]

Acute Lymphoblastic Leukemia

In animals, exposure to benzene and other chemicals can cause leukemia. [wiki.clinicalflow.com]

Exposure to chemicals: Exposure to benzene, which is present in cigarette smoke and petroleum products, may increase the risk. [medicalnewstoday.com]

Exposure to chemicals : Exposure to benzene, which is present in cigarette smoke and petroleum products, may increase the risk. [medicalnewstoday.com]

Acute Myeloid Leukemia with 11q23 Abnormalities

Chemical and Other Exposures Exposure to benzene, a solvent used in the chemical, plastic, rubber, and pharmaceutical industries, is associated with an increased incidence [accessmedicine.mhmedical.com]

[…] to alkylating agents, radiation, topoisomerase II inhibitors) Occupational exposures (radiation, benzene, petroleum products, paint, smoking, pesticides) 16. [slideshare.net]

exposure. [wiki.clinicalflow.com]

Severe Aplastic Anemia

Doctors have also identified some of the possible causes of this immune system response, including: exposure to benzene, a chemical used to make plastics, synthetic fibers [medicalnewstoday.com]

Aplastic anemia can be caused by: Use of certain drugs or exposure to toxic chemicals (such as chloramphenicol, benzene) Exposure to radiation or chemotherapy Autoimmune disorders [nlm.nih.gov]

dyes, detergents, and pesticides insecticide exposure nonviral hepatitis pesticide exposure medications, such as chemotherapy drugs or chloramphenicol hepatitis pregnancy [medicalnewstoday.com]

Acute Myeloid Leukemia with Myelodysplasia-Related Changes

They include: Repeated exposure to the chemical benzene, as well as other chemicals like it called fluorocarbons, which are found in cigarette smoke, petroleum products and [aamds.org]

While some studies have suggested a link between occupational exposure to benzene and increased risk of AML,[13] others have suggested the attributable risk, if any, is slight [en.wikipedia.org]

Benzene and many of its derivatives are known to be carcinogenic in vitro. [en.wikipedia.org]

Acute Myeloid Leukemia with Recurrent Genetic Anomaly

These include: previous chemotherapy or radiotherapy exposure to very high levels of radiation (including previous radiotherapy treatment) exposure to benzene – a chemical [nhs.uk]

Exposure to benzene can produce aplastic anaemia and pancytopenia. This can progress to AML, usually of the M6 variant. [patient.info]

While some studies have suggested a link between occupational exposure to benzene and increased risk of AML, [13] others have suggested the attributable risk, if any, is slight [en.wikipedia.org]