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6 Possible Causes for Extensive Fatty Infiltration on Biopsy

  • Arrhythmogenic Right Ventricular Dysplasia

    The biopsy, taken form right ventricular free wall, revealed extensive replacement-type fibrosis and fatty infiltration.[] Endomyocardial biopsy showed extensive replacement by fibrous tissue [18].[] (d, e) Endomyocardial biopsy features. Extensive replacement-type fibrosis (Trichrome stain 5).[]

  • Nodular Localized Cutaneous Amyloidosis

    The biopsy specimen showed extensive deposition of pale eosinophilic amorphous material through the entire dermis into the fatty tissue, with dense infiltration of plasma[] (c) A CT study showed a swollen hilar lymph node (red arrows), consistent with sarcoidosis Click here to view Skin-punch biopsy (4 mm) was performed for the nodule on the[]

  • Myotonic Dystrophy

    Late in the disease (II-5, II-6, II-7, II-8), extensive myofibre loss and fatty infiltration with moderate fibrosis were encountered.[] The muscle biopsy was normal in only one patient (III-36).[]

  • Carnitine Deficiency

    Abstract We report the case of a patient who at age 39 first developed an episode of muscle weakness and transient ketoacidosis with biopsy proven fatty infiltration of the[] Over the next several years, myopathy ensued; biopsy revealed extensive deposition of lipid globules in type 1 muscle fibres.[]

  • Navajo Poikiloderma

    fatty infiltration on biopsy; Focal lymphocytic and macrophage infiltrates on biopsy; Loss of lower-limb tendon reflexes; Lymphedema of upper and/or lower limbs (in some[] Contractures of upper limbs (in some patients); Muscle weakness of proximal and distal upper and lower limbs; Muscle wasting; Myogenic profile on electromyography; Adiposis on MRI; Extensive[]

  • Autosomal Dominant Centronuclear Myopathy

    Muscle magnetic resonance imaging (MRI) revealed an extensive fatty infiltration in the posterior thigh and distal leg muscles, with severe involvement in the bilateral adductor[] Muscle biopsy was performed for the patient’s left biceps muscle and revealed numerous central nuclei in most of the muscle fibers, with disrupted myofibril and type 1 fiber[]

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