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75 Possible Causes for Extrapyramidal Symptoms May Occur

  • Amyotrophic Lateral Sclerosis Type 10

    Amyotrophic lateral sclerosis (ALS) is a progressive and generally fatal motor neuron disease. Most cases are sporadic, but high familial incidence is observed occasionally. Amyotrophic lateral sclerosis 10 (ALS10) is one of many subtypes of familial ALS. It has been related to mutations in the TARDBP gene, a[…][]

  • Alzheimer Disease

    […] be overlooked, especially in later stages of the illness, until the patient experiences significant extrapyramidal symptoms while receiving an antipsychotic.[] If this occurs, the drug should be discontinued and a diagnosis of dementia with Lewy bodies entertained.[] […] antipsychotics. 57 - 61 Although dementia with Lewy bodies is characterized by fluctuating levels of impairment, hallucinations (often visual), and parkinsonism, the diagnosis may[]

  • Dementia

    Antipsychotic drugs used to treat hallucinations, delusions and agitation can dramatically worsen cognitive and extrapyramidal symptoms and may lead to severe, and even fatal[] The combination of psychotic features and parkinsonism which occurs in DLB and PDD can be particularly difficult to manage.[]

  • Psychosis

    Neuroleptic malignant syndrome may occur as well. Effects on the Central Nervous System: Drowsiness, sedation, and hypnosis occur.[] Side Effects and Adverse Drug Reactions People who take antipsychotic medications may experience negative side effects, such as: Extrapyramidal Effects: Dystonias, akathisia[] , tardive dyskinesia, Parkinson’s-like symptoms, unwanted movements, ataxia, muscle breakdown, rigidity, tremors, and seizures are some major effects of this category of drugs[]

  • Bipolar Disorder

    In general, the incidence of extrapyramidal symptoms (EPS) or neuroleptic malignant syndrome is lower with atypical antipsychotics than with the conventional antipsychotics[] , but may still occur and should be monitored.[ 11 ] As a group, these medications may cause significant weight gain in youths, and subsequent metabolic problems such as an[]

  • Migraine Equivalent

    Accumulation may occur at higher than recommended doses, with an increased incidence of adverse effects ( Sibelium ; Irish SPC).[] Flunarizine should be used with caution in older people, and people taking flunarizine should be assessed at regular intervals for the development of extrapyramidal symptoms[]

  • Hypocalcemia

    Neuropsychiatric manifestations include dementia in adults, anxiety, depression, lethargy, and extrapyramidal symptoms (parkinsonism).[] Papilledema, cataracts, basal ganglia calcifications, and skin, hair, and dental changes may occur with chronic hypocalcemia.[] Skin exam may show dermatitis, eczema, hyperpigmentation, psoriasis, brittle hair with patchy alopecia, and brittle nails with characteristic transverse grooves.[]

  • Olivopontocerebellar Atrophy

    Abnormalities of the spinal cord and some of the cranial nerves may also occur. Symptoms usually begin at approximately twenty-five years of age.[] Olivopontocerebellar Atrophy V (OPCA V; OPCA with dementia and extrapyramidal signs) is characterized by cerebellar atrophy, tremors, ataxia and abnormal sensation, rigidity[]

  • Phenothiazine Poisoning

    Pseudoparkinsonism and other extrapyramidal symptoms may occur but are infrequent.[]

  • Extrapyramidal Disorder

    Other causes of EPS may include cerebral palsy and brain damage that affects the extrapyramidal system.[] This type of extrapyramidal symptom may result with antipsychotic medications.[] Tricyclic antidepressants – Amoxapine, a tricyclic antidepressant drug also causes extrapyramidal symptoms.[]

Further symptoms