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230 Possible Causes for Extremity Ataxia, Hepatomegaly, Progressive Polyneuropathy

  • Chronic Alcoholism

    Hepatomegaly (in chronic alcoholic liver disease the liver is shrunken). Ascites; gonadal atrophy. Atrial fibrillation and cardiomyopathy.[] Characteristic ultrasonographic findings include a hyperechoic liver with or without hepatomegaly.[] Most patients with moderate disease are undernourished and present with fatigue, fever, jaundice, right upper quadrant pain, tender hepatomegaly, and sometimes a hepatic bruit[]

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[] We describe a case of a young black woman with gradually progressive lower extremity paresthesias, weakness, and ataxia as the primary presenting symptoms of pernicious anemia[] Hepatomegaly and splenomegaly may be present.[]

  • Vitamin B12 Deficiency

    […] names or words Radiculopathy - chronic pain disorder Increased susceptibility to infections Poor wound healing Malnutrition Enlarged spleen (splenomegaly) Enlarged liver (hepatomegaly[] peripheral neuropathy, and spinal degeneration.[] In later stages, spasticity, extensor plantar responses, greater loss of position and vibratory sensation in the lower extremities, and ataxia emerge.[]

  • POEMS Syndrome

    Hepatomegaly was significantly reduced after the completion of BorCyDex.[] Before the implementation of aPBSCT, the clinical course of POEMS syndrome was characterized by progressive polyneuropathy potentially leading to death for respiratory failure[] Neurologic examination revealed upper and lower extremity weakness with bilateral foot drop and gait ataxia requiring crutches for ambulation and bilateral foot braces.[]

  • Vasculitis

    In addition to the classical ones, KD may be manifested through a wide variety of symptoms including diarrhoea, hepatomegaly, jaundice, arthritis, myocarditis, pericarditis[] Neuropathy Sensory or Sensory-Motor General patterns Mononeuritis multiplex (13%) Asymmetric polyneuropathy (85%) Distal symmetric polyneuropathy (2%) More slowly progressive[] CRYOGLOBULINEMIA (CRYOGLOBULINEMIA WITH VASCULITIS) Type II mixed cryoglobulinemia (MC) is characterized by recurrent purpura, arthralgias / arthritis, weakness, peripheral neuropathy, hepatomegaly[]

  • Thiamine Deficiency

    Physical examination: pallor, tachycardia, hepatomegaly.[] Nerve conduction studies were consistent with axonal, length-dependent polyneuropathy.[] After 2 to 3 months apathy and weakness become extreme, calf muscle tenderness develops with loss of recent memory, confusion, ataxia, and sometimes persistent vomiting ([]

  • Arsenic-Induced Polyneuropathy

    Our interest in the problem arose because we observed some patients, who were opium addicts, having a clinical picture of arsenical neuropathy * and hepatomegaly.[] ., sensory ataxia due to vitamin B 12 deficiency) Deep tendon reflexes References: [10] [11] [12] [9] Subtypes and variants Diabetic polyneuropathy Definition : progressive[] […] jerks, tremors, seizures, an impaired ability to coordinate voluntary movements (ataxia), and/or inability to stand or walk.[]

  • Castleman Disease

    Examination revealed pallor; generalized edema; axillary, cervical, and inguinal lymphadenopathy; hypertension; and hepatomegaly.[] Progressive motor polyneuropathy suggesting coexistent POEMS does not respond well to rituximab or to IL-6–targeted therapy, and these patients require autologous stem cell[] […] in association with a total ophtalmoplegia and a dysphagia, consistent with the Miller-Fisher syndrome (ophtalmoplegia, ataxia, and areflexia).[]

  • Polyneuropathy

    While about 20% of patients will have hepatomegaly, 75% will have hepatic granulomas.[] Convert to ICD-10-CM : 356.4 converts directly to: 2015/16 ICD-10-CM G60.3 Idiopathic progressive neuropathy Approximate Synonyms Idiopathic progressive neuropathy Polyneuropathy[] There are only sensory symptoms, e.g. sensory ataxia, numbness and pain.[]

  • Familial Progressive Polyneuropathy

    While about 20% of patients will have hepatomegaly, 75% will have hepatic granulomas.[] Abstract The purpose of this study was to evaluate the clinical and pathological features in patients with progressive-type familial amyloidotic polyneuropathy (FAP) using[] […] with marked disturbances of sensation and ataxia of movement and caused by an interstitial hypertrophic neuritis that ascends with consecutive medullary [cord] lesions.[]

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