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163 Possible Causes for Extremity Ataxia, Iron Increased, Progressive Polyneuropathy

  • Vitamin B12 Deficiency

    peripheral neuropathy, and spinal degeneration.[ncbi.nlm.nih.gov] In later stages, spasticity, extensor plantar responses, greater loss of position and vibratory sensation in the lower extremities, and ataxia emerge.[merckmanuals.com] You may also develop anemia due to iron deficiency and you can read my other post about the top signs of iron deficiency and how to increase iron levels in your blood .[healthyandnaturalworld.com]

  • Chronic Alcoholism

    Wernicke-Korsakoff syndrome (ataxia, confusion, ophthalmoplegia), amnesic problems, peripheral neuropathy and dementia.[patient.info] Coexisting iron accumulation or chronic hepatitis C increases risk of hepatocellular carcinoma.[merckmanuals.com] Other factors that may trigger type 1 PCT include oestrogen, iron and viral infections (especially hepatitis C).[dermnetnz.org]

  • Pernicious Anemia

    We describe a case of a young black woman with gradually progressive lower extremity paresthesias, weakness, and ataxia as the primary presenting symptoms of pernicious anemia[ncbi.nlm.nih.gov] Individuals suffering iron deficiency might take oral iron supplements and increase their dietary iron intake, while individuals suffering from pernicious anemia might receive[livestrong.com] ), ataxia and positive Babinski reflexes.[doi.org]

  • Heavy Metal Poisoning

    In addition, non-inflammatory degenerative disease of the sensorimotor nerves (sensorimotor polyneuropathy) may advance to progressive deterioration (atrophy).[rarediseases.org] Local villagers ate the fish and began to exhibit signs of neurologic damage, such as visual loss, extremity numbness, hearing loss, and ataxia.[slideshare.net] Low iron increases toxicity of cadmium and lead, causing impaired cognitive function.[drmyhill.co.uk]

  • Vasculitis

    Neuropathy Sensory or Sensory-Motor General patterns Mononeuritis multiplex (13%) Asymmetric polyneuropathy (85%) Distal symmetric polyneuropathy (2%) More slowly progressive[neuromuscular.wustl.edu] Abstract Deferasirox is an iron chelator agent used in the treatment of diseases with iron overload, such as thalassemia and myelodysplastic syndrome.[ncbi.nlm.nih.gov] Sensory loss: Large Small fiber modalities Gait: Sensory ataxia; Romberg positive Motor: Normal strength Tendon reflexes: Absent or Reduced Course Neuropathy onset: 1 to[neuromuscular.wustl.edu]

  • Guillain-Barré Syndrome

    Guillain-Barré syndrome is a rare condition in pregnancy which is characterised by symmetrical progressive ascending polyneuropathy.[ncbi.nlm.nih.gov] , and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk.[icd10data.com] Pradal, Abnormally increased iron concentration in basal ganglia in Shy-Drager syndrome MR imaging and autonomic study: RM imagem e estudo autonômico, Arquivos de Neuro-Psiquiatria[oadoi.org]

  • Thiamine Deficiency

    Nerve conduction studies were consistent with axonal, length-dependent polyneuropathy.[ncbi.nlm.nih.gov] […] is one potential way of increasing micronutrient intake in resource limited populations....[ennonline.net] After 2 to 3 months apathy and weakness become extreme, calf muscle tenderness develops with loss of recent memory, confusion, ataxia, and sometimes persistent vomiting ([wardelab.com]

  • Arsenic-Induced Polyneuropathy

    ., sensory ataxia due to vitamin B 12 deficiency) Deep tendon reflexes References: [10] [11] [12] [9] Subtypes and variants Diabetic polyneuropathy Definition : progressive[amboss.com] […] jerks, tremors, seizures, an impaired ability to coordinate voluntary movements (ataxia), and/or inability to stand or walk.[rarediseases.org] Consider a hereditary cause, long-term toxic exposure, or a metabolic disorder if patients have a slowly progressive chronic polyneuropathy.[merckmanuals.com]

  • Autosomal Recessive Spinocerebellar Ataxia Type 17

    Clinical features Ataxia, chorea, and axonal polyneuropathy Cutaneous photosensitivity and multiple cancers Mental and motor retardation Microcephaly Sensorineural deafness[emedicine.medscape.com] […] the extremities, truncal ataxia, increased reflexes in the lower extremities, and intellectual disability.[malacards.org] Hereditary hemochromatosis (HHC) is characterized by inappropriately increased iron absorption from the duodenum and upper intestine, with consequent deposition in various[aetna.com]

  • Lethal Ataxia with Deafness and Optic Atrophy

    […] external ophthalmoplegia, sensorimotor polyneuropathy MRI: leukoencephalopathy (but they have no CNS dysfunction) Holocarboxylase Synthase Def AKA early-onset multiple carboxylase[quizlet.com] […] the diagnosis, and an extreme diet that also rid me of dairy, I do not remember feeling better in my adult life.[glutendude.com] Clinical features in P3 were particularly misleading for an OPA1 related condition, with manifestations of early onset progressive spastic ataxia and sensory motor polyneuropathy[link.springer.com]

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