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486 Possible Causes for Extremity Ataxia, Progressive Polyneuropathy

  • Vitamin B12 Deficiency

    peripheral neuropathy, and spinal degeneration.[ncbi.nlm.nih.gov] In later stages, spasticity, extensor plantar responses, greater loss of position and vibratory sensation in the lower extremities, and ataxia emerge.[merckmanuals.com] ) Hypotonia (low muscle tone) Reduced tactile sensation Seizures Ataxia (lack of muscle control) Symptoms of paralysis Involuntary movements Concentration problems Memory[stichtingb12tekort.nl]

  • Chronic Alcoholism

    Wernicke-Korsakoff syndrome (ataxia, confusion, ophthalmoplegia), amnesic problems, peripheral neuropathy and dementia.[patient.info] Investigations Alcohol level is useful in acute comatose state: Alcohol level 300 mg/100 ml extreme intoxication (drowsiness and then coma).[patient.info]

  • Vasculitis

    Sensory loss: Large Small fiber modalities Gait: Sensory ataxia; Romberg positive Motor: Normal strength Tendon reflexes: Absent or Reduced Course Neuropathy onset: 1 to[neuromuscular.wustl.edu] Neuropathy Sensory or Sensory-Motor General patterns Mononeuritis multiplex (13%) Asymmetric polyneuropathy (85%) Distal symmetric polyneuropathy (2%) More slowly progressive[neuromuscular.wustl.edu] Neuropathy 10 Predisposing factors Previous infection: C. jejuni Clinical: Upper respiratory infection most common Onset: Paresthesias Clinical Sensory Paresthesias: Distal extremities[neuromuscular.wustl.edu]

  • Paraneoplastic Syndrome

    We report a fatal case of severe chronic progressive axonal polyradiculoneuropathy in association with this antibody.[doi.org] Cerebellar symptoms : ataxia, unsteady gait, dysdiadochokinesia, intention tremor Note that symptoms often emerge months before the discovery of a primary tumor ![amboss.com] It is usually a distal sensorimotor polyneuropathy that causes mild motor weakness, sensory loss, and absent distal reflexes.[merckmanuals.com]

  • Chronic Inflammatory Demyelinating Polyneuropathy

    On admission, the patient exhibited bifacial, extremity weakness, ataxia, impaired sensation, and areflexia. Electrophysiology and nerve biopsy suggested demyelination.[ncbi.nlm.nih.gov] Shortly after HSCT the patient developed progressive polyneuropathy of the lower legs and hypoesthesia. Five months later a severe dementia followed.[ncbi.nlm.nih.gov] Neuropathic pain in affected extremities may occur.[emedicine.medscape.com]

  • Diabetic Polyneuropathy

    Ms Q is a 52-year-old woman who has had progressive polyneuropathy in the setting of diabetes for the past 8 years.[ncbi.nlm.nih.gov] Deep tendon reflexes were symmetric and graded 2 in all extremities.[openaccessjournals.com] They are distributed in LLll extremities and may evolve to UULL and characteristically patients refer worsening at night.[scielo.br]

  • Pernicious Anemia

    We describe a case of a young black woman with gradually progressive lower extremity paresthesias, weakness, and ataxia as the primary presenting symptoms of pernicious anemia[ncbi.nlm.nih.gov] ), ataxia and positive Babinski reflexes.[doi.org] Consequently, the neurologic effects may include neuritis, weakness in the extremities, peripheral numbness and paresthesias (an abnormal sensation like tingling or burning[innvista.com]

  • Guillain-Barré Syndrome

    Guillain-Barré syndrome is a rare condition in pregnancy which is characterised by symmetrical progressive ascending polyneuropathy.[ncbi.nlm.nih.gov] , and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk.[icd10data.com] An 81-year-old man presented with fever, confusion and rapidly-progressive flaccid tetraparesis.[ncbi.nlm.nih.gov]

  • Thiamine Deficiency

    Nerve conduction studies were consistent with axonal, length-dependent polyneuropathy.[ncbi.nlm.nih.gov] After 2 to 3 months apathy and weakness become extreme, calf muscle tenderness develops with loss of recent memory, confusion, ataxia, and sometimes persistent vomiting ([wardelab.com] […] voice, inattention, ataxia, and binocular diplopia after a voluntary 59-kg weight loss over 5 months.[ncbi.nlm.nih.gov]

  • Familial Progressive Polyneuropathy

    […] with marked disturbances of sensation and ataxia of movement and caused by an interstitial hypertrophic neuritis that ascends with consecutive medullary [cord] lesions.[karger.com] Abstract The purpose of this study was to evaluate the clinical and pathological features in patients with progressive-type familial amyloidotic polyneuropathy (FAP) using[ncbi.nlm.nih.gov] The familial occurrence of axonal and slowly progressive polyneuropathy led us to consider these patients as candidates for TTR molecular analysis.[ncbi.nlm.nih.gov]

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