pharyngitis frequently absent - lymphadenopathy less common Heterophile antibody negative - IgM class antibody that agglutinate RBC from certain species like sheep Infects
[brainscape.com]
Specimen Requirements Specimen Vesicular fluid, ulcerated lesions, pharyngeal and throat swabs, urine, cerebrospinal fluid (CSF), autopsy and biopsy material, eye exudates
[labcorp.com]
The vesicles rupture to form ulcerative lesions with grayish exudates on the tonsils and the posterior pharynx.
[emedicine.medscape.com]