Create issue ticket

1,516 Possible Causes for 'Eye of the Tiger' Sign on MRI, Flexion Contracture, Mask-like Facies

  • Parkinson's Disease

    Facial expression is blunted, described as a "masked facies". The patient typically has difficulty with the initiation of movement.[clinicaladvisor.com] Passive extension and flexion at the elbow can feel like ratcheting, described as cog-wheel rigidity. B.[clinicaladvisor.com]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Parkinson's Disease Type 3

    Parkinson's disease type 3 (PD3) is a form of Parkinson's disease that is inherited in an autosomal dominant manner. The underlying mutation has not yet been identified, but PD3 has been related to a 2.5 Mb-locus on the short arm of chromosome 2. To date, PD3 has been diagnosed in distinct families in Europe and[…][symptoma.com]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Diffuse Scleroderma

    contracture 0001371 Malabsorption Intestinal malabsorption 0002024 Muscle weakness Muscular weakness 0001324 Osteolysis Breakdown of bone 0002797 Pulmonary fibrosis 0002206[rarediseases.info.nih.gov] With disease progression, ulcerations over joints and flexion contractures of the fingers, wrists, and elbows may occur.[aafp.org] Flexion contractures may develop in the fingers, wrists, and elbows. Friction rubs may develop over the joints, tendon sheaths, and large bursae.[merckmanuals.com]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Freeman-Sheldon Syndrome

    A six-day-old girl, born to normal non-consanguineous parents presented with mask like facies with a small mouth giving a 'whistling' appearance.[ncbi.nlm.nih.gov] In addition to other deformities, limb myopathy results in ulnar flexion contractures of the hand and equinovarus/valgus deformities of the feet.[ncbi.nlm.nih.gov] 1975; Joseph Harold Sheldon, British physician, 1920-1964 An autosomal dominant [MIM 193700] or less commonly, or autosomal recessive [MIM 277720] condition with atypical mask-like[medical-dictionary.thefreedictionary.com]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Malignant Hyperthermia - Arthrogryposis - Torticollis

    facies Expressionless face Lack of facial expression Mask-like facial appearance [ more ] 0000298 Metatarsus adductus Front half of foot turns inward 0001840 Plagiocephaly[rarediseases.info.nih.gov] contracture of toe Shoulder flexion contracture Abnormal facial shape Renal insufficiency Pectus excavatum Joint contracture of the hand Dental malocclusion Cachexia Narrow[mendelian.co] 30%) HP:0006610 18 webbed neck 59 32 hallmark (90%) Very frequent (99-80%) HP:0000465 19 hyperconvex fingernails 59 32 occasional (7.5%) Occasional (29-5%) HP:0001812 20 mask-like[malacards.org]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Systemic Scleroderma

    With disease progression, ulcerations over joints and flexion contractures of the fingers, wrists, and elbows may occur.[aafp.org] contracture 0001371 Malabsorption Intestinal malabsorption 0002024 Muscle weakness Muscular weakness 0001324 Osteolysis Breakdown of bone 0002797 Pulmonary fibrosis 0002206[rarediseases.info.nih.gov] contractures Prayer or steeple sign (inability to directly bring hands together because fingers will not fully extend) Muscle atrophy (secondary to myositis [overlap syndrome[aafp.org]

    Missing: 'Eye of the Tiger' Sign on MRI
  • X-linked Parkinsonism-Spasticity Syndrome

    T2-weighted fast spin echo (G) and T1-weighted (H) brain MRI scans from a child with PKAN demonstrating the "eye of the tiger" sign (courtesy of Susan J.[ojrd.biomedcentral.com] T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[neuroweb.us] Onset can be later, with more rigidity in atypical forms of PKAN [ 12 ], but the typical MRI findings of the "eye of the tiger" sign suggest the diagnosis.[ojrd.biomedcentral.com]

    Missing: Flexion Contracture
  • Juvenile Paralysis Agitans of Hunt

    Parkinsonismo precoce associado a lesões palidais de tipo "eye-of-the-tiger" "Eye-of-the-tiger" sign at MRI in a patient with early-onset parkinsonism Egberto Reis Barbosa[scielo.br]

    Missing: Flexion Contracture
  • Secondary Myopathy

    Later joint contractures occur in the neck, resulting in reduced neck flexion.[sites.google.com] Emery-Dreifuss muscular dystrophy presents with more significant contractures, and ambulation is generally preserved into the patient’s twenties.[sites.google.com] Contractures at biceps, elbows, at gastrocnemius, ankles (Achilles tendon), and neck (extensors) contractures occur. Toe walking is an early presentation of EDMD.[sites.google.com]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Platyspondyly

    […] hyperthermia Abnormality of the ureter Sprengel anomaly Increased number of teeth Spinal rigidity Laryngomalacia High pitched voice Abnormality of immune system physiology Myotonia Mask-like[mendelian.co] contracture SOURCES: MONDO UMLS ORPHANET OMIM More info about SPONDYLOEPIPHYSEAL DYSPLASIA, STANESCU TYPE; SEDSTN Low match CZECH DYSPLASIA Czech dysplasia is an autosomal[mendelian.co] contracture Childhood-onset short-trunk short stature Proximal femoral metaphyseal irregularity Increased vertebral height Femoral bowing present at birth, straightening[mendelian.co]

    Missing: 'Eye of the Tiger' Sign on MRI

Similar symptoms