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1,208 Possible Causes for 'Eye of the Tiger' Sign on MRI, Jerk-Locked Premyoclonus Spikes, Slow Speech

  • Hallervorden-Spatz Syndrome

    Iron deposition in conjunction with destruction of the globus pallidus gives rise to the characteristic eye-of-the-tiger sign in MRI.[ncbi.nlm.nih.gov] These abnormalities progressed over the years with slowing of voluntary movements, rigidity of limbs and dystonic posturing. Speech was slurred.[jpgmonline.com] Intermediate forms manifest onset in first decade with slow progression or onset in second decade with rapid progression.[genecards.org]

    Missing: Jerk-Locked Premyoclonus Spikes
  • Benign Adult Familial Myoclonic Epilepsy

    T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[neuroweb.us] […] cortical spikes detected by the jerk-locked back-averaging) ( Ikeda et al., 1990 ).[academic.oup.com] spikes detected by the jerk-locked back averaging (JLA) method), and a good response to antiepileptic drugs. 2 BAFME was first reported in 1990 in the Japanese population[nature.com]

    Missing: Slow Speech
  • Juvenile Paralysis Agitans of Hunt

    speech rate -cranial polyneuropathy presenting as recurrent unilateral painful ophthalmoplegia -CN 2, 3, 4, V1, and 6 may be involved -tendency for spontaneous resolution[cram.com] Parkinsonismo precoce associado a lesões palidais de tipo "eye-of-the-tiger" "Eye-of-the-tiger" sign at MRI in a patient with early-onset parkinsonism Egberto Reis Barbosa[scielo.br] , quieter speech, and monotone voice Urinary frequency/urgency SLIDESHOW Parkinson's Disease: Symptoms, Causes, Stages, Treatment See Slideshow What causes Parkinson's disease[medicinenet.com]

    Missing: Jerk-Locked Premyoclonus Spikes
  • Alcoholic Cerebellar Degeneration

    T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[neuroweb.us] Slowed and slurred speech 5. Nystagmus (quick, small actions of the eyes.) Is there a known treatment for Alcoholic Cerebellar Degeneration?[hncmag.com] A 41 yo female with slow progressive ataxia, slurred speech since last 15 years. Truncal ataxia on neurological examination.[neuroradiologycases.com]

    Missing: Jerk-Locked Premyoclonus Spikes
  • Acute Alcohol Intoxication

    speech ( n 21; 8.20%), imbalance ( n 25; 9.77%) Passive ( n 43; 16.80%), somnolence ( n 62; 24.21%), slow speech ( n 72; 28.13%), impossible assess balance ( n 78; 30.47%[academic.oup.com] Confusion, slurred speech. Internal (stomach and intestinal) bleeding. Slowed breathing. Stupor (decreased level of alertness), even coma. Unsteady walking.[nlm.nih.gov] speech ( n 44; 17.19%), imbalance ( n 50; 19.53%) Restful behaviour ( n 41; 16.02%), somnolence ( n 51; 19.92%), slow speech ( n 48; 18.75%), impossible assess balance ([academic.oup.com]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Senile Chorea

    Her MRI did not show the typical “eye of the tigersign or pronounced low signal in the globus pallidus without the additional inserted bright signal that has now been well[jnnp.bmj.com] Modest improvements were seen in symptoms including: motor coordination, speech intelligibility and vocal intensity, bradykinesia (slow movement), emotional functions, activities[goodearthnaturalfoods.com]

    Missing: Jerk-Locked Premyoclonus Spikes
  • Epilepsia Partialis Continua

    Jerk-locked back averaging (JLA) of magnetoencephalogram disclosed a spike preceding the jerk localized at the hand motor area, whereas JLA of electroencephalogram revealed[ncbi.nlm.nih.gov] […] no premyoclonus spikes.[ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Alcohol Abuse

    A high concentration of alcohol in the blood causes symptoms, such as: slurred speech slowing of reflexes a decreased ability to control bodily movements difficulty concentrating[healthline.com]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Hypoglycemia

    speech Convulsions Unconsciousness Treatment Immediately eat or drink something containing "quick acting" sugar.[uihc.org] Nervousness Hunger Dizziness Faintness Pounding heart Personality change Confused thinking Impatience Crankiness Numbness of lips and tongue Headache Blurred Vision Slurred or slow[uihc.org]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Subacute Cerebellar Degeneration

    Get the patient to stick his/her tongue out and move it from side to side (movement slowed).[patient.info] T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[neuroweb.us] Ask the patient to repeat "baby hippopotamus" - look for dysarthria and abnormal speech rhythm and syllable emphasis.[patient.info]

    Missing: Jerk-Locked Premyoclonus Spikes