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136 Possible Causes for 'Eye of the Tiger' Sign on MRI, Photoparoxysmal Response

  • Benign Adult Familial Myoclonic Epilepsy

    Photoparoxysmal responses (PPR) were noted in 18 (95%) patients with BAFME but 1 (10%) with EGTCS.[] T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[] Response 3 progressive myoclonus epilepsy Spastic Paraplegia with Myoclonic Epilepsy[]

  • Juvenile Myoclonic Epilepsy

    responses (PPRs).[] PURPOSE: Juvenile myoclonic epilepsy (JME) is commonly associated with photoparoxysmal response (PPR) with a reported prevalence of 25-42%.[] Photic stimulation disclosed a marked photoparoxysmal response, sometimes associated with myoclonic jerks.[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Photosensitive Epilepsy

    A flashing strobe light, for example, can trigger a photoparoxysmal response in a predisposed individual.[] The second patient's photoparoxysmal response was suppressed by both parallel-polarized and blue cross-polarized glasses, whereas the third patient's photoparoxysmal response[] Methods Seven participants with a photoparoxysmal response to intermittent photic stimulation (IPS) at baseline were randomized in a double-blind, 4-period cross-over study[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Idiopathic Generalized Epilepsy

    Other characteristic EEG features include polyspikes, polyspike-wave discharges, occipital intermittent rhythmic delta activity, and photoparoxysmal response.[] PURPOSE: Photosensitivity or photoparoxysmal response (PPR) is an electroencephalography trait that is highly associated with idiopathic generalized epilepsies (IGEs) and[] response, variable response of AS to intravenous benzodiazepines, and usually good seizure control with valproate.[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Hallervorden-Spatz Syndrome

    Iron deposition in conjunction with destruction of the globus pallidus gives rise to the characteristic eye-of-the-tiger sign in MRI.[] […] of the tiger" sign.[] It has been postulated that pantothenate kinase 2 mutations underlying all cases of classic Hallervorden-Spatz syndrome are always associated with the eye-of-the-tiger sign[]

    Missing: Photoparoxysmal Response
  • Unverricht-Lundborg Syndrome

    Background activity kept stable during the course of the disease; generalized paroxysmal discharges and photoparoxysmal response gradually disappeared with a significant difference[] GLOSSARY ANOVA analysis of variance ; KM Kaplan-Meier ; PHT phenytoin ; PME progressive myoclonus epilepsy ; PPR photoparoxysmal responses ; PSW polyspikes and waves ; SSEP[] Left: marked photosensitivity with generalized photoparoxysmal response (PPR). Right: normal background activity, no PPR.[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Progressive Myoclonic Epilepsy Type 8

    With doses of up to 10 g/day, elimination of photoparoxysmal responses was achieved in all 3 patients.[] Intermittent light stimulation generated a photoparoxysmal response at low frequencies. Epileptic activity did not increase during stages of drowsiness.[] response; (i) giant SEPs and hyperexcitability of the C-reflex ( Figure 8-2 ); and (j) cortical EEG potential time locked to the jerks.[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Neuronal Ceroid Lipofuscinosis 2

    […] with a photoparoxysmal response associated with other epilepsy syndromes.[] EEGs revealed a photoparoxysmal response (PPR) on intermittent photic stimulation in 93% (13 of 14) of patients.[] Unique Characteristics of the photoparoxysmal response in patients with neuronal ceroid lipofuscinosis type 2: can EEG be a biomarker? J Child Neurol. 2016;31:1475-1482.[]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Neurodegeneration with Brain Iron Accumulation

    Individuals with PKAN and HARP syndrome, which is considered part of the PKAN disease spectrum, show a characteristic "eye of the tiger''sign on MRI, a central region of hyperintensity[] sign in cranial MRI, this case most likely represented an idiopathic form of NBIA but atypical PKAN may be also considered.[] For all of the disorders in this category, T 2 -weighted brain MRI would distinguish PKAN based on the presence of the "eye of the tiger" sign.[]

    Missing: Photoparoxysmal Response
  • Tonic-Clonic Seizure

    Before seizure onset, IPS consistently induced generalized photoparoxysmal responses (PPRs).[]

    Missing: 'Eye of the Tiger' Sign on MRI

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