Facial Lipoatrophy: Causes & Reasons

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Possible Causes for Facial Lipoatrophy

SHORT Syndrome

This six-year-old girl shows nearly all the typical manifestations reported in patients with the SHORT syndrome, including lipoatrophy, minor facial anomalies, Rieger anomaly [ncbi.nlm.nih.gov]

Common clinical features include intrauterine and postnatal growth restriction, lipoatrophy, characteristic facial gestalt, anterior chamber defects and insulin resistance [ncbi.nlm.nih.gov]

We describe a boy with the manifestations of the SHORT syndrome: lipoatrophy, delayed speech development, minor facial anomalies, clinodactyly, and short stature. [ncbi.nlm.nih.gov]

Lipodystrophy

What causes facial lipoatrophy? [poz.com]

While there may be some reversal of the condition, most predominately facial wasting (known a facial lipoatrophy), most reversals tend to be minimal to moderate. [aids.about.com]

[…] for patients with HIV-associated facial lipoatrophy (FLA). [aidsmap.com]

Nestor-Guillermo Progeria Syndrome

Néstor-Guillermo progeria syndrome (NGPS; OMIM 614008) is characterized by early onset and slow progression of symptoms including poor growth, lipoatrophy, pseudosenile facial [utsouthwestern.pure.elsevier.com]

facial appearance, and normal cognitive development. [onlinelibrary.wiley.com]

Definition An atypical progeroid syndrome characterized by normal development in the first years of life, later followed by the emergence of generalized lipoatrophy, severe [uniprot.org]

HIV Wasting Syndrome

What causes facial lipoatrophy? [poz.com]

Anatomy of Facial Wasting Surgical Treatment Since facial lipoatrophy affects the buccal fat pad and the surrounding tissue, Dr. [facechange.org]

How soon after HIV infection can facial wasting/ lipodystrophy/lipoatrophy occur? [lookfordiagnosis.com]

Partial Acquired Lipodystrophy Associated with C3 Nephritic Factor

Carruthers, A 2001 Facial lipoatrophy. J Cutan Med Surg 5 33 PubMed 26. Oral, EA, Simha, V, Ruiz, E, et al. 2002 Leptin-replacement therapy for lipodystrophy. [springermedizin.de]

Carruthers, A 2001 Facial lipoatrophy. J Cutan Med Surg 5 33 PubMed Google Scholar 26. [link.springer.com]

Facial lipoatrophy leads to an emaciated appearance with loss of buccal fat, triangular depression below the cheekbone, nummular depression at the temples, and a seemingly [dermaamin.com]

Silicone Granuloma

Jones D Injectable silicone for facial lipoatrophy Cosmetic Dermatol 2002;1513- 15Google Scholar 10. [jamanetwork.com]

Highly purified 1000-cSt silicone oil for treatment of human immunodeficiency virus-associated facial lipoatrophy: an open pilot trial. Dermatol Surg 2004;30:1279–1286. [e-aps.org]

[…] rhytides and in investigational protocols for human immunodeficiency virus–related lipoatrophy and severe facial deformities.6,7 There is enormous controversy regarding the [jamanetwork.com]

Facial Granuloma

Cheek augmentation with Bio-Alcamid in facial lipoatrophy in HIV seropositive patients. J Craniofac Surg 2008;19:1085-8. DOI PubMed [parjournal.net]

Long-term safety and efficacy of poly-L-lactic acid in the treatment of HIV-related facial lipoatrophy. HIV Med. 7: 181, 2006. 2. [journals.lww.com]

Polyacrylamide hydrogel injection in the management of human immunodeficiency virus-related facial lipoatrophy: a 2-year clinical experience. [parjournal.net]

Familial Partial Lipodystrophy

lipoatrophy in patients with HIV-1 protease inhibitor induced disease. [ncbi.nlm.nih.gov]

Familial partial lipodystrophy HIV lipoatrophy Lipoatrophy due to HIV infection and treatment Lipodystrophy of face Lipodystrophy, congenital Lipodystrophy, facial Clinical [icd9data.com]

Lipoatrophy due to hiv infection and treatment Lipodystrophy Lipodystrophy of face Lipodystrophy, congenital Lipodystrophy, facial Clinical Information A collection of heterogenous [icd10data.com]

Acquired Partial Lipodystrophy

She underwent surgical correction of facial lipoatrophy, with good aesthetic results. [ncbi.nlm.nih.gov]

There was progressive loss of facial fat for the last 3 years [Figure 1]. [ijem.in]

Lipoma of Buttock

Retreatment with injectable poly-l-lactic acid for HIV-associated facial lipoatrophy: 24-month extension of the Blue Pacific study. [aetna.com]

Milder facial lipoatrophy (james scale score 1 to 2) on initial presentation required fewer re-treatments and had more sustained correction. [aetna.com]

lipoatrophy. [aetna.com]

Acquired Generalized Lipodystrophy

A physical examination revealed facial lipoatrophy, with loss of buccal fat pads and prominent zygomatic arches. She presented bilateral breast hypoplasia. [bmcresnotes.biomedcentral.com]

The magnitude of the elevation in lipid levels and the associated symptoms exhibited by this patient constitute the most severe presentation of generalized lipoatrophy seen [doi.org]

Facial Hemiatrophy

Yoshimura et al. [ 8, 9 ] used this technique in patients with facial lipoatrophy and cosmetic breasts augmentation with excellent results. [e-aps.org]

Injectable hyaluronic acid for the correction of HIV-associated facial lipoatrophy. Otolaryngol Head Neck Surg. 2007 Apr;136(4):563-7. [de.slideshare.net]

Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells. Dermatol Surg 2008;34:1178–1185. PMID: 18513295. 9. [e-aps.org]

Cutis Verticis Gyrata

Manifestations of lipodystrophy included facial lipoatrophy ( ) and increased dorsocervical fat deposits ( ). [hindawi.com]

Conclusion In summary, our patients with CVG, who also have HIVLD (clinically diagnosed facial lipoatrophy and objective evidence of obesity and central fat accumulation), [hindawi.com]

Efavirenz Toxicity

Facial Lipoatrophy Severity Scale Facial lipoatrophy most often has been associated with long-term receipt of stavudine, didanosine, or the combination of stavudine plus didanosine [hivwebstudy.org]

Polylactic acid and calcium hydroxylapatite injections can provide short-term benefit for facial lipoatrophy 5, 8 ; and liposuction and administration of recombinant growth [aafp.org]

HIV-associated facial lipoatrophy. Dermatol Surg. 2002;28:979-86. Figure 5. [hivwebstudy.org]

Skin Disease

While the lifespan is prolonged by the use of HAART, many HIV-infected patients are troubled by drug-induced facial lipoatrophy. [info.gov.hk]

Discoid Lupus Erythematosus

We want to report a young male patient with progressive symmetrical facial lipoatrophy. In addition, he has discoid lupus erythematosus and celiac disease. [ncbi.nlm.nih.gov]

To our knowledge, this case involves the first male patient in the literature presenting with symmetrical facial lipoatrophy with very prominent periorbital lipoatrophy and [ncbi.nlm.nih.gov]

Literature review reveals studies involving 10 patients until today with lipoatrophy due to or after the onset of discoid lupus erythematosus; all are female patients. [ncbi.nlm.nih.gov]

Blepharoptosis

After having received ART for 19 months, the patient presented with lipodystrophy, with facial and peripheral lipoatrophy and intra-abdominal obesity. [academic.oup.com]

After 2.7 years of ART, she developed lipodystrophy with hypertriglyceridemia, hypercholesterolemia, facial and peripheral lipoatrophy, and intra-abdominal obesity. [academic.oup.com]

After 2 years of ART, he developed lipodystrophy that included hypertriglyceridemia, hypercholesterolemia, facial and peripheral lipoatrophy, dorsocervical fat accumulation [academic.oup.com]

Congenital Generalized Lipodystrophy Type 2

Affected adults may first be seen in the plastic surgery clinic seeking cosmetic improvement of facial lipoatrophy or in the cardiology clinic or gastroenterology clinic for [ncbi.nlm.nih.gov]

Presentation in the first months of life includes failure to thrive (or conversely gigantism), hepatomegaly, lipoatrophy, facial dysmorphia, enlarged tongue, or developmental [ncbi.nlm.nih.gov]

All children with the neonatal or infantile presentation demonstrate lipoatrophy in the first year of life. [ncbi.nlm.nih.gov]

Congenital Generalized Lipodystrophy Type 1

Affected adults may first be seen in the plastic surgery clinic seeking cosmetic improvement of facial lipoatrophy or in the cardiology clinic or gastroenterology clinic for [ncbi.nlm.nih.gov]

Presentation in the first months of life includes failure to thrive (or conversely gigantism), hepatomegaly, lipoatrophy, facial dysmorphia, enlarged tongue, or developmental [ncbi.nlm.nih.gov]

All children with the neonatal or infantile presentation demonstrate lipoatrophy in the first year of life. [ncbi.nlm.nih.gov]

Abacavir

These side effects of anti-HIV drug therapy are reviewed in our lessons on Lipodystrophy, Facial Lipoatrophy, and Risks To Your Heart (Hyperlipidemia). How does it work? [hivandhepatitis.com]

HIV-associated facial lipoatrophy. Dermatol Surg. 2002;28:979-86. Figure 5. [hivwebstudy.org]

Interstitial Lung Disease with Brain Calcifications Type Rajab

Affected adults may first be seen in the plastic surgery clinic seeking cosmetic improvement of facial lipoatrophy or in the cardiology clinic or gastroenterology clinic for [ncbi.nlm.nih.gov]

Presentation in the first months of life includes failure to thrive (or conversely gigantism), hepatomegaly, lipoatrophy, facial dysmorphia, enlarged tongue, or developmental [ncbi.nlm.nih.gov]

All children with the neonatal or infantile presentation demonstrate lipoatrophy in the first year of life. [ncbi.nlm.nih.gov]

Donohue Syndrome

Affected adults may first be seen in the plastic surgery clinic seeking cosmetic improvement of facial lipoatrophy or in the cardiology clinic or gastroenterology clinic for [ncbi.nlm.nih.gov]

Donohue syndrome is characterized by unique facial features like globular eyes, micrognathia, severe intra uterine growth retardation, lipoatrophy, early onset severe fasting [ijpeonline.biomedcentral.com]

Presentation in the first months of life includes failure to thrive (or conversely gigantism), hepatomegaly, lipoatrophy, facial dysmorphia, enlarged tongue, or developmental [ncbi.nlm.nih.gov]

Wiedemann-Rautenstrauch Syndrome

A peculiar facial appearance is characterized by a triangular old-looking face, sparse hair, low-set ears and eyes, scanty eyebrows, facial bone hypoplasia, prominent scalp [whonamedit.com]

Loss of fat tissue in localized area 0100578 Loss of facial adipose tissue Decreased amount of facial fat Loss of facial fat [ more ] 0000292 Malar flattening Zygomatic flattening [rarediseases.info.nih.gov]

Arboleda et al. (1997) also described radiographic features including craniofacial disproportion, large sutures and fontanels, global hypoplasia of the facial bones, and thin [omim.org]

Nakajo Syndrome

[…] and limbs lipoatrophy, and developmental (height, weight, and IQ) retardation. [genome.jp]

Lipoatrophy and joint contractures occurred progressively in life, mainly on the upper part of the body, leading to a very characteristic facial appearance. [frontiersin.org]

[…] degrees Celsius), steroid-sensitive erythema nodosum-like (edematous and purpuric) plaques, long clubbed fingers, hyperhidrosis, myositis, hepatosplenomegaly, macroglossia, facial [genome.jp]

Hypertrichosis

[…] based BioForm Medical, be approved for use in restoring facial contours such as nasolabial folds and in treating facial lipoatrophy associated with HIV. 20% want cosmetic [web.archive.org]

Insulin Resistance

[…] dysmorphism,exuberant scalp and body hair, severe acanthosis, lipoatrophy, dental abnormalities, and short stature (Rabson-Mendenhall phenotype). [ncbi.nlm.nih.gov]

[…] insulin receptor signalling, noted primarily in children, and is often difficult to diagnose due to the clinical heterogeneity.SEIR was diagnosed in an adolescent girl with facial [ncbi.nlm.nih.gov]

Metabolic Syndrome

Possible interventions include autologous fat transfer, dermal fillers or muscle grafts to treat facial lipoatrophy; surgical reduction or liposuction of areas with excessive [ncbi.nlm.nih.gov]

Acne Vulgaris

Polylactic acid implants (New-Fill) to correct facial lipoatrophy in HIV-infected patients: results of the open-label study VEGA. [doi.org]

Jackson-Weiss Syndrome

Lipoatrophy: Facial Fat Loss With Deepening of Nasolabial Fold Figure 3. Fat Accumulation: Abdominal (Visceral) Obesity Figure 4. [thebodypro.com]

The disfigurement resulting from facial lipoatrophy and the potential for extreme psychological distress create an urgent need for research into other modalities of palliative [thebodypro.com]

Poly-L-lactic acid, a biodegradable synthetic polymer, is the only product currently approved by the US Food and Drug Administration (FDA) for the treatment of facial lipoatrophy [thebodypro.com]

Coats Plus Syndrome

Injectable hyaluronic acid for the correction of HIV-associated facial lipoatrophy. Otolaryngol Head Neck Surg. 2007 Apr;136(4):563-7. [de.slideshare.net]

Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells. Dermatol Surg. 2008 Sep;34(9):1178-85. Epub 2008 May 29. [de.slideshare.net]

[Plaque-type scleroderma associated with linear and oesophageal features and facial and extra-facial hemiatrophy]. Ann Dermatol Venereol. 2007 Jan;134(1):68-71. French. [de.slideshare.net]