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2,255 Possible Causes for Facial Muscle Weakness and Progressive Atrophy, Grip Strength Decreased, Muscle Hypotonia

  • Motor Neuron Disease

    Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[] Loss of lower motor neurons causes denervation atrophy of muscle, manifested by severe hypotonia, weakness, and inability to breathe.[] Progressive bulbar palsy , also called progressive bulbar atrophy, involves the brain stem—the bulb-shaped region containing lower motor neurons needed for swallowing, speaking[]

  • Brachial Plexus Neuropathy

    We describe brachial plexus neuropathy with high-dose cytarabine (Ara-C) therapy in a man who had acute monoblastic leukemia. Signs and symptoms of brachial plexus neuropathy appeared on two occasions within hours of exposure to high-dose Ara-C. Central nervous system complications have been described following[…][]

    Missing: Facial Muscle Weakness and Progressive Atrophy
  • Amyotrophic Lateral Sclerosis

    Prior animal studies have shown that silencing SOD1 led to preservation of grip strength and a delay in the onset of motor function deficits [ 125, 126 ].[] In cranial nerves, common symptoms are atrophy of facial muscles and progressive bulbar palsy (PBP).[] Symptoms may include hypotonia (severely reduced muscle tone), diminished limb movements, lack of tendon reflexes, fasciculations, tremors, swallowing and feeding difficulties[]

  • Myotonic Dystrophy

    Clinical Presentation: Variable, progressive disability; facial and distal limb muscle weakness with myotonia; cataracts; cardiac conduction defects; diabetes mellitus; and[] It is characterized by muscle wasting and hypotonia, cataracts, heart conduction defects and endocrinopathies.[] The clinical course led progressively to major disability with severe proximal weakness and atrophy and, later on, distal weakness, atrophy and neck extensor weakness responsible[]

  • Neuromuscular Junction Disorder

    His grip is slightly weak at 4 . Strength doesn't decrease or increase with repeated trials.[] Signs: there is ptosis, facial weakness, atrophy of the sternocieidomastoid muscles, cataracts, and decreased intelligence.[] Manifestations include muscle weakness; fasciculation; muscle atrophy; spasm; myokymia; muscle hypertonia, myalgias, and muscle hypotonia.[]

  • Lambert Eaton Myasthenic Syndrome

    MuSK MG should be considered if there is facial or tongue weakness with atrophy, or weakness that predominates in neck or shoulder muscles.[] Neonates and infants with CMS experience generalized weakness, delayed motor milestone, and hypotonia with an evidence of wasted muscle bulk over time along with an evidence[] MG follows a variable course, but usually progresses.[]

  • Muscular Dystrophy-Dystroglycanopathy Type C14

    Specifically, LGMD2B is a slowly progressive disease that causes muscle weakness and wasting ( atrophy ) of the pelvic muscles and muscles of the shoulder girdle. 0003236[] In such cases, affected individuals have severe muscle weakness of both the arms and legs, loss of muscle tone (hypotonia), and delays in attaining motor milestones.[] DM1 should be suspected in newborns who present with one or any of the following: Hypotonia Facial muscle weakness Generalized weakness Positional malformations including[]

    Missing: Grip Strength Decreased
  • Muscular Dystrophy-Dystroglycanopathy Type C4

    There is often asymmetric quadriceps, hamstring, biceps, brachioradialis, or calf weakness and atrophy. Muscle pain is common.[] Fukuyama congenital muscular dystrophy is a more severe disorder characterized by brain malformations, hypotonia and muscle weakness.[] Signs and symptoms are often present before birth but sometimes start in infancy and include weak muscle tone (hypotonia), excess fluid on the brain (hydrocephalus), severe[]

    Missing: Grip Strength Decreased
  • Limb-Girdle Muscular Dystrophy

    The forearms may become mildly atrophic with decrease in grip strength; the small muscles of the hands are spared.[] In such cases, affected individuals have severe muscle weakness of both the arms and legs, loss of muscle tone (hypotonia), and delays in attaining motor milestones.[] […] ambulating, waddling gait, and hypotonia.[]

    Missing: Facial Muscle Weakness and Progressive Atrophy
  • Glycogen Storage Disease Type 2

    grip strength and decreased ability to jump and hop. 99 Significant weakness attributable to debrancher deficiency most often is recognized in adult life. 21, 53, 58 In the[] […] deficiency; large amounts of glycogen accumulate in the lysosomes of skeletal muscle, heart, liver, spinal cord, and brain; three forms have been described: the infantile[] hypotonia respiratory distress Juvenile and adult form skeletal myopathy delayed-gross motor development limb-girdle weakness respiratory issues Enzyme replacement therapy[]

    Missing: Facial Muscle Weakness and Progressive Atrophy

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