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10 Possible Causes for Facial Muscle Weakness and Progressive Atrophy, Grip Strength Decreased, Muscular Atrophy

  • Amyotrophic Lateral Sclerosis

    The patients were a 54-year-old man with progressive muscular atrophy who underwent removal of internal fixators in the arm and leg, and a 66-year-old woman with amyotrophic[ncbi.nlm.nih.gov] Prior animal studies have shown that silencing SOD1 led to preservation of grip strength and a delay in the onset of motor function deficits [ 125, 126 ].[doi.org] Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org]

  • Motor Neuron Disease

    Some MNDs, such as ALS and some forms of spinal muscular atrophy, are fatal.[ninds.nih.gov] Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org] A somewhat better prognosis is seen in progressive muscular atrophy, where patients live up to 25 years.[symptoma.com]

  • Myotonic Dystrophy

    Neuromuscular disorders like myotonic dystrophy (dystrophia myotonica or Steinert's disease) and spinal muscular atrophy are associated with perioperative complications related[ncbi.nlm.nih.gov] Clinical Presentation: Variable, progressive disability; facial and distal limb muscle weakness with myotonia; cataracts; cardiac conduction defects; diabetes mellitus; and[ajnr.org] New contributions to the theory of muscular atrophy in supranuclear paralysis especially in cerebral hemiplegia (Habilitationsschrift).[doi.org]

  • Muscular Atrophy

    - muscle Amyotrophia edit English muscular atrophy human disease Amyotrophia NOS Amyotrophia NOS (disorder) Muscle atrophy (disorder) Muscle wasting Muscular atrophy Wasting[wikidata.org] A hand-grip-strength test has been used to help diagnose sarcopenia in studies, and may be used in some clinics ( 18 ).[healthline.com] Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info]

  • Lambert Eaton Myasthenic Syndrome

    Spinal muscular atrophy.[patient.info] MuSK MG should be considered if there is facial or tongue weakness with atrophy, or weakness that predominates in neck or shoulder muscles.[docksci.com] The type 2 fiber atrophy, found on the histochemical study of the brachial biceps muscular biopsy of both patients, is an non-specified finding.[scielo.br]

  • Neuromuscular Junction Disorder

    Spinal muscular atrophies: Amyotrophic lateral sclerosis (ALS), or motor neuron disease Infantile progressive spinal muscular atrophy Intermediate spinal muscular atrophy[hopkinsmedicine.org] His grip is slightly weak at 4 . Strength doesn't decrease or increase with repeated trials.[mda.org] Signs: there is ptosis, facial weakness, atrophy of the sternocieidomastoid muscles, cataracts, and decreased intelligence.[academic.sun.ac.za]

  • Distal Myopathy Type 3

    Marked facial weakness is observed in these patients with congenital myopathies. [2] Spinal Muscular Atrophy Distal spinal muscular atrophy is an autosomal recessive infantile[explainmedicine.com] The forearms may become mildly atrophic with decrease in grip strength; the small muscles of the hands are spared.[ncbi.nlm.nih.gov] The following features are however constantly present: atrophy of the intrinsic hand muscles, facial muscle involvement, myotonia and dystrophic changes in nonmuscular tissue[neuroweb.us]

  • Fingerprint Body Myopathy

    He is currently involved in multiple clinical trials of novel genetic interventions for the treatment of spinal muscular atrophy and Duchenne muscular dystrophy.[books.google.com] His grip is slightly weak at 4 . Strength doesn't decrease or increase with repeated trials.[mda.org] Within few years the disease progressed to generalized muscle weakness and atrophy, ptosis, ophthalmoplegia externa and areflexia.[scipers.com]

  • Inclusion Body Myositis

    Sporadic inclusion body myositis (sIBM) is a slowly progressive, red-rimmed vacuolar myopathy leading to muscular atrophy and progressive weakness; it predominantly affects[ncbi.nlm.nih.gov] By 14 months, there was a significant decrease in muscle force in mutant VCP mice ( P 0.0001; n 10), as assessed by longitudinal analysis of grip strength as well as acute[doi.org] […] disease of middle-aged , beginning in legs, causing atrophy and weakness of quadriceps, sparing facial and oropharyngeal muscles EMG Abnormal electrical 'irritation', slowing[medical-dictionary.thefreedictionary.com]

  • Miyoshi Myopathy Type 2

    Abstract Miyoshi myopathy (MM) is an early adult-onset, autosomal recessive disorder characterized by weakness and muscular atrophy starting in the distal muscles.[ncbi.nlm.nih.gov] The forearms may become mildly atrophic with decrease in grip strength. It is caused by mutations in the DYSF gene and is inherited in an autosomal recessive manner.[diseaseinfosearch.org] There is often asymmetric quadriceps, hamstring, biceps, brachioradialis, or calf weakness and atrophy. Muscle pain is common.[emedicine.medscape.com]

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