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10 Possible Causes for Facial Muscle Weakness and Progressive Atrophy, Grip Strength Decreased, Weight Loss

  • Amyotrophic Lateral Sclerosis

    loss in the early stages.[ncbi.nlm.nih.gov] Prior animal studies have shown that silencing SOD1 led to preservation of grip strength and a delay in the onset of motor function deficits [ 125, 126 ].[doi.org] In cranial nerves, common symptoms are atrophy of facial muscles and progressive bulbar palsy (PBP).[flexikon.doccheck.com]

  • Lambert Eaton Myasthenic Syndrome

    RESULTS: Age at onset, smoking behavior, weight loss, Karnofsky performance status, bulbar involvement, male sexual impotence, and the presence of Sry-like high-mobility group[ncbi.nlm.nih.gov] MuSK MG should be considered if there is facial or tongue weakness with atrophy, or weakness that predominates in neck or shoulder muscles.[docksci.com] More than 50 years of age at onset of symptoms, positive history for smoking, weight loss, bulbar symptoms, male sexual impotence and Karnofsky performance status lower than[symptoma.com]

  • Motor Neuron Disease

    We describe a 52-year-old man with body weight loss and bulbar palsy, who exhibited muscle atrophy and weakness with fasciculation especially in the respiratory muscles 4[ncbi.nlm.nih.gov] Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org] loss, and reduced survival.[ncbi.nlm.nih.gov]

  • Myotonic Dystrophy

    Dysphagia is one of the most problematic symptoms of DM1 because it may cause weight loss, aspiration pneumonias or sudden death.[ncbi.nlm.nih.gov] Clinical Presentation: Variable, progressive disability; facial and distal limb muscle weakness with myotonia; cataracts; cardiac conduction defects; diabetes mellitus; and[ajnr.org] The clinical course led progressively to major disability with severe proximal weakness and atrophy and, later on, distal weakness, atrophy and neck extensor weakness responsible[doi.org]

  • Distal Myopathy Type 3

    loss Sweating Tremor Neck swelling Decreased TSH Non specific Myotonic Hypothyroidism [8] 55 Proximal Rhabdomyolysis Signs of hypothyroidism H/o weight gain Myxoedema Muscle[wikidoc.org] The forearms may become mildly atrophic with decrease in grip strength; the small muscles of the hands are spared.[ncbi.nlm.nih.gov] The following features are however constantly present: atrophy of the intrinsic hand muscles, facial muscle involvement, myotonia and dystrophic changes in nonmuscular tissue[neuroweb.us]

  • Inclusion Body Myositis

    The most common symptoms were muscle weakness, falls, dysphagia, and weight loss. Hypertension was the main comorbidity.[ncbi.nlm.nih.gov] By 14 months, there was a significant decrease in muscle force in mutant VCP mice ( P 0.0001; n 10), as assessed by longitudinal analysis of grip strength as well as acute[doi.org] […] disease of middle-aged , beginning in legs, causing atrophy and weakness of quadriceps, sparing facial and oropharyngeal muscles EMG Abnormal electrical 'irritation', slowing[medical-dictionary.thefreedictionary.com]

  • Muscular Atrophy

    Summary: Noticeable loss of strength or stamina and unintentional weight loss are signs of multiple diseases, including sarcopenia.[healthline.com] Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] A hand-grip-strength test has been used to help diagnose sarcopenia in studies, and may be used in some clinics ( 18 ).[healthline.com]

  • Neuromuscular Junction Disorder

    The patient may describe tightness in the throat, and may complain of pooling of secretions as well as develop insidious weight loss.[nature.com] His grip is slightly weak at 4 . Strength doesn't decrease or increase with repeated trials.[mda.org] Signs: there is ptosis, facial weakness, atrophy of the sternocieidomastoid muscles, cataracts, and decreased intelligence.[academic.sun.ac.za]

  • Fingerprint Body Myopathy

    Cytoplasmic body neuromyopathy presenting as respiratory failure and weight loss. J Neurol Sci 1979;41:1-9. 5. Edstrom L, Thronell LE, Eriksson A.[myslide.es] His grip is slightly weak at 4 . Strength doesn't decrease or increase with repeated trials.[mda.org] Within few years the disease progressed to generalized muscle weakness and atrophy, ptosis, ophthalmoplegia externa and areflexia.[scipers.com]

  • Miyoshi Myopathy Type 2

    Loss and Lung Nodules 411 Case 65 A Woman with Difficulty Walking and Ataxia 415 Case 66 A Man with Progressive Neuropathy and Congestive Heart Failure 422 Case 67 An Elderly[books.google.de] The forearms may become mildly atrophic with decrease in grip strength. It is caused by mutations in the DYSF gene and is inherited in an autosomal recessive manner.[diseaseinfosearch.org] There is often asymmetric quadriceps, hamstring, biceps, brachioradialis, or calf weakness and atrophy. Muscle pain is common.[emedicine.medscape.com]

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