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9,243 Possible Causes for Facial Numbness, Fatigue, Mutation in the Tight Junction Protein 2 Gene

  • Herpes Zoster

    It is particularly likely if there is facial infection.[dermnetnz.org] There were no significant differences between groups for the following AEs: any grade 3 symptom, any general symptom, any general grade 3 symptom, fatigue, grade 3 fatigue[doi.org] In rare cases, herpes can infect the facial or eye nerves.[aidsinfonet.org]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Stroke

    A 48-year-old man presented with acute onset of left facial numbness, ataxic gait and double vision.[ncbi.nlm.nih.gov] He had 3 months history of fatigue, fever, and weight loss. Neurological examination revealed left hemiparesis and dysarthria.[ncbi.nlm.nih.gov] The symptoms may be mild or dramatic and can mimic a stroke with weakness, numbness, facial droop, and speech difficulties, but these symptoms may only last a few minutes.[medicinenet.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Anxiety Disorder

    […] characterized by at least 6 months of pervasive and excessive anxiety; recurring worry about common events; and physical symptoms, such as muscle tension, insomnia, and fatigue[doi.org] However, GAD was also highly associated with impaired psychological well-being, stress and fatigue (p CONCLUSIONS: In AMI patients, GAD was independently associated with less[ncbi.nlm.nih.gov] […] routine visit, a 59-year-old woman, who describes herself as a lifetime “worrier” and has a family history of depression, reports having restless sleep, muscle tension, and fatigue[doi.org]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Migraine

    A 45-year-old woman with a 20-year history of migrainous headaches presented with complaints of rightsided facial and hand numbness and paraesthesia.[ncbi.nlm.nih.gov] Adverse events included paresthesia, fatigue, nausea, and anorexia.[aafp.org] Patients may also experience nausea, vomiting, anorexia, neck pain, dizziness, changes in hearing, light sensitivity, difficulty concentrating, facial numbness or weakness[migrainepal.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Primary Progressive Multiple Sclerosis

    Facial numbness and weakness are also common.[medical-dictionary.thefreedictionary.com] “We also have additional data that shows we have an effect on fatigue (a very important aspect of MS, 75% of patients have fatigue).[mdmag.com] Fatigue is also common with this and all other forms of multiple sclerosis.[verywell.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Multiple Sclerosis

    , tingling, or pain: Facial pain Painful muscle spasms Tingling, crawling, or burning feeling in the arms and legs Other brain and nerve symptoms: Decreased attention span[nlm.nih.gov] Fatigue was measured by questionnaires (i.e.[ncbi.nlm.nih.gov] Fatigue Management in Multiple Sclerosis .[dx.doi.org]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Occult Malignancy

    Holzner B, Kemmler G, Greil R, Kopp M, Zeimet A, Raderer M, Hejna M, Zochbauer S, Krajnik G, Huber H: The impact of hemoglobin levels on fatigue and quality of life in cancer[karger.com] […] in pregnancy Cancer metastatic to bone Cancer metastatic to ovary Cancer metastatic to parotid gland Cancer metastatic to vagina Cancer of unknown primary Cancer related fatigue[icd10data.com] […] identifiable primary site, despite exhaustive tests. [ 1 ] Presentation Most patients present with advanced-stage cancers and therefore usually have symptoms of malaise, weakness, fatigue[patient.info]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Basilar-Type Migraine

    Intense emotional stimuli (74%) and sleep disorders (65%) were the most common trigger factors, followed by change in weather, sunshine, cold wind, acute stress, alcohol, and fatigue[ncbi.nlm.nih.gov] […] published in the journal Pain Medicine identified these as the ones most involved: Intense emotional situations Sleep disorders Weather Sunlight Cold wind Stress Alcohol Fatigue[verywell.com] The acute phase may be accompanied by nausea, vomiting, chills, polyuria, sweating, facial edema, irritability, and extreme fatigue.[medical-dictionary.thefreedictionary.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Pseudohypoparathyroidism

    Paraesthesiae (tingling, vibrating, burning and numbness) of the face, fingers and toes. Facial twitching. Carpopedal spasm. Stridor. Convulsions (usually grand mal).[patient.info] The patient presented with general fatigue, steppage gait, and myalgia.[ncbi.nlm.nih.gov] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 14, 2019[patientslikeme.com]

    Missing: Mutation in the Tight Junction Protein 2 Gene
  • Hypomagnesemia

    It has been recently attributed to a mutation in the Claudin 16 (CLDN 16) gene of the Paracellin-1 (PCLN-1) tight junction protein.[ncbi.nlm.nih.gov] We first observed this phenomenon in a 34-year-old male patient with metastatic colorectal cancer who developed profound fatigue and symptomatic hypocalcemia and hypomagnesemia[ncbi.nlm.nih.gov] A 53-year-old man, with history of recurrent joint effusions and pains affecting knees and wrists, had transient episodes of muscle pain, weakness, cramping, and fatigue over[ncbi.nlm.nih.gov]

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