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34 Possible Causes for Facial Swelling, Hyperpigmentation, Prolactin Increased

  • Acromegaly

    […] eyelids Increased body hair ( hypertrichosis ), excessive sweating ( hyperhidrosis ), and oily skin ( seborrhoea ) Increased number of skin tags and darkening of the skin ( hyperpigmentation[dermnetnz.org] This leads to coarse facial features, soft tissue swelling (including the tongue), enlargement of the hands and feet, respiratory problems, hypertension, diabetes mellitus[ncbi.nlm.nih.gov] […] in serum prolactin levels (43.2 ng/mL).[ncbi.nlm.nih.gov]

  • Cushing's Disease

    The disease manifests with signs of CS (truncal and facial obesity and signs of hypercatabolism) as well as skin hyperpigmentation and/or neurological complications in some[orpha.net] The equations generally decreased the central-to-peripheral gradient on the uncorrected ACTH dominant side, increased the central-to-peripheral gradient on the contralateral[ncbi.nlm.nih.gov] Hyperpigmentation of the skin may occur due to the fact that circulating ACTH has some melanocyte stimulating hormone (MSH) like activity.[symptoma.com]

  • Galactorrhea-Amenorrhea Syndrome

    Thyroid: exopthalmos, goiter, abnormal deep tendon reflexes Hyperandrogenism: hirsuitism, acne, hair loss Hypercortisolemia: striae, hyperpigmentation Pelvic exam The labs[sketchymedicine.com] (soft tissue enlargement) coarsening of facial features change in ring or shoe size spreading teeth, bite difficulties (overbite/underbite) Bell's palsy (facial paralysis[pituitary.mgh.harvard.edu] In the three women effectively treated with pyridoxine, the galactorrhea returned, serum prolactin levels increased, and the menses ceased after discontinuing pyridoxine.[ncbi.nlm.nih.gov]

  • Chlorpromazine

    It suggests that long-term chlorpromazine therapy, even with low drug doses, may lead to hyperpigmentation disorders in skin and/or eye.[ncbi.nlm.nih.gov] The third patient had development of facial edema involving the ipsilateral eyelids, forehead, and cheek. Strikingly, it extended to the contralateral face.[ncbi.nlm.nih.gov] […] doses Therapy is associated with increased prolactin levels; significance unknown May cause pigmentary retinopathy, and lenticular and corneal deposits with prolonged therapy[reference.medscape.com]

  • Pituitary Adenoma

    (soft tissue enlargement) coarsening of facial features change in ring or shoe size spreading teeth, bite difficulties (overbite/underbite) Bell's palsy (facial paralysis[pituitary.mgh.harvard.edu] Prolactinomas increase blood levels of prolactin.[imperialendo.com] […] cardiomegaly, heat intolerance, weight gain ACTH ( 20%) Cushing's disease : central obesity (moon facies, buffalo hump), thin skin with striae, hirsutism Nelson's syndrome : hyperpigmentation[en.wikibooks.org]

  • Carney Complex

    Abstract We report an illustrated case of a 61-year-old woman with multiple atrial myxomas and cutaneous hyperpigmentation as part of the Carney complex.[ncbi.nlm.nih.gov] Abstract A 22-year-old male became unconscious and was found to have left-sided weakness and facial asymmetry.[ncbi.nlm.nih.gov] Acromegaly due to a pituitary GH-secreting tumor is not very frequent, but most patients with CNC present with a mild increase in GH, and sometimes in prolactin (PRL) secretion[ncbi.nlm.nih.gov]

  • Small Cell Carcinoma of the Lung

    swelling Call your doctor immediately if you’re experiencing any of these symptoms.[healthline.com] Within seventeen months she developed florid Cushing's syndrome with anasarca, hyperpigmentation, hypertension with marked hypercortisolemia (not suppressible with 8 mg dexamethasone[ncbi.nlm.nih.gov] […] symptoms may include: bloody mucus from the lungs shortness of breath wheezing chest pain or discomfort a persistent cough or hoarseness a loss of appetite weight loss fatigue facial[healthline.com]

  • Purging-Type Bulimia Nervosa

    Patients with chronic laxative use can have colonic hyperpigmentation (melanosis coli).[acphospitalist.org] […] in the hands and feet Facial and cheek swelling from enlarged glands Causes The exact cause of bulimia is unknown.[mayoclinic.org] […] eating, during meals or for long periods of time Exercising too much Having sores, scars or calluses on the knuckles or hands Having damaged teeth and gums Changing weight Swelling[mayoclinic.org]

  • Acne Vulgaris

    Abstract A case of persistent solid facial edema is described in a 17-year-old boy with moderate papulocystic acne.[ncbi.nlm.nih.gov] : prolactin receptors are well expressed in the adrenal glands.[ncbi.nlm.nih.gov] Post-inflammatory hyperpigmentation after acne can be as troublesome as the acne itself.[ncbi.nlm.nih.gov]

  • Angiofibroma

    Although these treatments have proven to be successful, they can result in scarring, post-inflammatory hyperpigmentation, and pain.[statpearls.com] A plethora of other symptoms may be present, including a headache, facial pain, facial swelling, rhinorrhea, hyposmia, ipsilateral hearing loss and diplopia.[symptoma.com] Pituitary adenomas are common as well, and present with signs and symptoms of increased secretion of prolactin, growth hormone, or adrenocorticotropin hormone.[dermatologyadvisor.com]

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